PURPOSE: To report on a case of bilateral conjunctival lymphoid hyperplasia pr esenting with bilateral panuveitis in a female patient. DESIGN: Observational ca se report. METHODS: In this case excisional biopsy indica...PURPOSE: To report on a case of bilateral conjunctival lymphoid hyperplasia pr esenting with bilateral panuveitis in a female patient. DESIGN: Observational ca se report. METHODS: In this case excisional biopsy indicated lymphoid tissue. Im munohistochemistry showed a follicular architecture with appropriate zoning of B and T lymphocytes. RESULTS: Causes of panuveitis were considered and excluded b ased on a detailed history, physical examination, and laboratory investigations. The bilateral panuveitis resolved on topical corticosteroids and visual acuity returned to normal. CONCLUSIONS: Ocular adnexal lymphoproliferative lesions cons ist of a spectrum of disease entities, including reactive lymphoid hyperplasia, atypical lymphoid hyperplasia, and lymphoma. There are no established clinical c riteria to differentiate between these lesions. This case highlights the importa nce of a thorough ophthalmic examination in these patients, as an intra-ocular inflammatory process may accompany the conjunctival findings. Futhermore, we adv ocate periodic follow-up examinations because of the small potential risk of de veloping ocular or systemic lymphoma in these patients.展开更多
文摘PURPOSE: To report on a case of bilateral conjunctival lymphoid hyperplasia pr esenting with bilateral panuveitis in a female patient. DESIGN: Observational ca se report. METHODS: In this case excisional biopsy indicated lymphoid tissue. Im munohistochemistry showed a follicular architecture with appropriate zoning of B and T lymphocytes. RESULTS: Causes of panuveitis were considered and excluded b ased on a detailed history, physical examination, and laboratory investigations. The bilateral panuveitis resolved on topical corticosteroids and visual acuity returned to normal. CONCLUSIONS: Ocular adnexal lymphoproliferative lesions cons ist of a spectrum of disease entities, including reactive lymphoid hyperplasia, atypical lymphoid hyperplasia, and lymphoma. There are no established clinical c riteria to differentiate between these lesions. This case highlights the importa nce of a thorough ophthalmic examination in these patients, as an intra-ocular inflammatory process may accompany the conjunctival findings. Futhermore, we adv ocate periodic follow-up examinations because of the small potential risk of de veloping ocular or systemic lymphoma in these patients.
