According to the literature data on the chemical composition of the Trichilia genus performed in this work, it can be concluded that 334 different compounds were isolated and identified, distributed in monoterpenes, s...According to the literature data on the chemical composition of the Trichilia genus performed in this work, it can be concluded that 334 different compounds were isolated and identified, distributed in monoterpenes, sesquiterpenes, diterpenes, triterpenes, steroids, limonoids, coumarins, flavonoids, lignans, phenolic acids, amino acids and lactones. Together with the structures of this compound, data from botanical classification and pharmaco-logical results from extracts and pure compounds on the Trichilia genus were also described. The compounds derived from terpenes pathway were more significant, corresponding to about 87.7% of isolated and identified compounds from various Trichilia species. Among the different terpenoid skeletons of this kind, limonoids were meanly reported, appearing a total of 33.9% of compounds isolated from several Trichilia species.展开更多
This study is a review of the Condamineeae tribe, through the acquisition of data from phytochemical studies and evaluation of genera activities that constitute the tribe, in order to contribute to chemotaxonomic clas...This study is a review of the Condamineeae tribe, through the acquisition of data from phytochemical studies and evaluation of genera activities that constitute the tribe, in order to contribute to chemotaxonomic classification of this tribe in the Rubiaceae family. This review also states the scarcity of phytochemical investigations of several genera and consequently a lot of species of family.展开更多
Species from Moraceae family stand out in popular medicine and phytotherapy, have been for example used as expectorants, bronchodilators, anthelmintics and treatment of skin diseases, such as vitiligo, due to the pres...Species from Moraceae family stand out in popular medicine and phytotherapy, have been for example used as expectorants, bronchodilators, anthelmintics and treatment of skin diseases, such as vitiligo, due to the presence of compounds with proven biological activity, as the coumarins. Coumarins are lactones with 1,2-benzopyrone basic structure, and are widely distributed in the plant kingdom, both in free form, and in glycosylated form. This work reports a literature review, describing the data of 13C NMR from 53 coumarins isolated from the family Moraceae, and data comparison between genera who presented photochemical studies, in order to contribute to the chemotaxonomy of this family.展开更多
A mixture of new ceramides (1, 2, 3, 4 and 5) together with a binary mixture of ceramides with long chain alkyl (6 and 7), triterpenoid (10) and steroids (11 and 12) have been isolated from bark of the fruits and of t...A mixture of new ceramides (1, 2, 3, 4 and 5) together with a binary mixture of ceramides with long chain alkyl (6 and 7), triterpenoid (10) and steroids (11 and 12) have been isolated from bark of the fruits and of the stems of Luffa operculata (Cucurbitaceae). The structures were elucidated by comprehensive spectro- scopic analysis including 1H and 13C NMR, DEPT (distortionless enhancement by polarization transfer), COSY (correlated spectroscopy), HMQC (heteronuclear multiple quantum coherence), HMBC (heteronu- clear multiple bond connectivity), IR (infrared), HR-ESI-MS (electrospray ionization-high resolution mass spectra) and LR-MS (low resolution electron ionization mass spectra) experiments. All the ceramides are reported for the first time in Cucurbitaceae and this is the first report of the rare triterpene 10 isolated from Luffa operculata. The ceramides 6 and 7 showed a high acetylcholine esterase inhibitory effect.展开更多
The dichloromethane extract of the air-dried stems of Trichilia casarettii afforded a new sesquiterpene (1), lupeol, stigmasterol, campesterol and sitosterol. The structure of 1 was elucidated by extensive one-and two...The dichloromethane extract of the air-dried stems of Trichilia casarettii afforded a new sesquiterpene (1), lupeol, stigmasterol, campesterol and sitosterol. The structure of 1 was elucidated by extensive one-and two- dimensional nuclear magnetic resonance and mass spectrometry.展开更多
基金The authors are thankful to FAPERJ,Fundacao Carlos Chagas Filho de AmparoàPesquisa do Estado do Rio de Janeiro(N˚do Processo E-26/111.898/2012)for financial support.
文摘According to the literature data on the chemical composition of the Trichilia genus performed in this work, it can be concluded that 334 different compounds were isolated and identified, distributed in monoterpenes, sesquiterpenes, diterpenes, triterpenes, steroids, limonoids, coumarins, flavonoids, lignans, phenolic acids, amino acids and lactones. Together with the structures of this compound, data from botanical classification and pharmaco-logical results from extracts and pure compounds on the Trichilia genus were also described. The compounds derived from terpenes pathway were more significant, corresponding to about 87.7% of isolated and identified compounds from various Trichilia species. Among the different terpenoid skeletons of this kind, limonoids were meanly reported, appearing a total of 33.9% of compounds isolated from several Trichilia species.
文摘This study is a review of the Condamineeae tribe, through the acquisition of data from phytochemical studies and evaluation of genera activities that constitute the tribe, in order to contribute to chemotaxonomic classification of this tribe in the Rubiaceae family. This review also states the scarcity of phytochemical investigations of several genera and consequently a lot of species of family.
文摘Species from Moraceae family stand out in popular medicine and phytotherapy, have been for example used as expectorants, bronchodilators, anthelmintics and treatment of skin diseases, such as vitiligo, due to the presence of compounds with proven biological activity, as the coumarins. Coumarins are lactones with 1,2-benzopyrone basic structure, and are widely distributed in the plant kingdom, both in free form, and in glycosylated form. This work reports a literature review, describing the data of 13C NMR from 53 coumarins isolated from the family Moraceae, and data comparison between genera who presented photochemical studies, in order to contribute to the chemotaxonomy of this family.
基金Fundacao Cearense de Amparo a Pesquisa do Estado do Ceara(FUNCAP)for grantsto Conselho Nacional do Desenvolvimento Cientifico e Tecnologico(CNPq-Brazil)for a research fellowship and grants.
文摘A mixture of new ceramides (1, 2, 3, 4 and 5) together with a binary mixture of ceramides with long chain alkyl (6 and 7), triterpenoid (10) and steroids (11 and 12) have been isolated from bark of the fruits and of the stems of Luffa operculata (Cucurbitaceae). The structures were elucidated by comprehensive spectro- scopic analysis including 1H and 13C NMR, DEPT (distortionless enhancement by polarization transfer), COSY (correlated spectroscopy), HMQC (heteronuclear multiple quantum coherence), HMBC (heteronu- clear multiple bond connectivity), IR (infrared), HR-ESI-MS (electrospray ionization-high resolution mass spectra) and LR-MS (low resolution electron ionization mass spectra) experiments. All the ceramides are reported for the first time in Cucurbitaceae and this is the first report of the rare triterpene 10 isolated from Luffa operculata. The ceramides 6 and 7 showed a high acetylcholine esterase inhibitory effect.
基金Fundacao de Amparo a Pesquisa do Estado do Rio de Janeiro(FAPERJ)for grantsto Conselho Nacional de Desenvolvimento Cientifico(CNPq-Brazil)for a research fellowship and grants.
文摘The dichloromethane extract of the air-dried stems of Trichilia casarettii afforded a new sesquiterpene (1), lupeol, stigmasterol, campesterol and sitosterol. The structure of 1 was elucidated by extensive one-and two- dimensional nuclear magnetic resonance and mass spectrometry.
