Super-enhancers are regions of the mammalian genome comprising multiple enhancers in close proximity and often enriched at cancer genes.^(1)Recent studies suggest the emerging roles of super-enhancer-associated genes ...Super-enhancers are regions of the mammalian genome comprising multiple enhancers in close proximity and often enriched at cancer genes.^(1)Recent studies suggest the emerging roles of super-enhancer-associated genes in un-derlying the cell identity of neuroblastoma(NB)2 which rises from neural crest-derived cells and is one of the most common malignant solid tumors in children.展开更多
基金supported by The National Natural Science Foundation of China(No.81770145,81802499,81971867,81970163,81902534,82072767,52003183,82141110)Natural Science Foundation of Jiangsu Province,China(No.SBK2019021442,BK20190185,BK20190186,BK20191175)+7 种基金The Universities Natural Science Foundation of Jiangsu Province,China(No.16KJB310014)Jiangsu province’s science and technology support program(Social Development)project,China(No.BE2021657,BE2021654)Jiangsu Province Key R&D Program(Social Development)Projects,China(No.BE2020659)Department of Pediatrics Clinical Center of Suzhou,China(No.Szzx201504)Gusu Health Talents program of Soochow city,China(No.2020-104)The Applied Foundational Research of Medical and Health Care of Suzhou City,China(No.SYS2019080,SYS2019082,SYS2019077,SYS2020150,SYS2020151,GSWS2020039)The Science and Technology Development Project of Suzhou City,China(No.SKJY2021111,a SKJY2021112)The Science and Technology Project of Soochow,China(No.SS2019011).
文摘Super-enhancers are regions of the mammalian genome comprising multiple enhancers in close proximity and often enriched at cancer genes.^(1)Recent studies suggest the emerging roles of super-enhancer-associated genes in un-derlying the cell identity of neuroblastoma(NB)2 which rises from neural crest-derived cells and is one of the most common malignant solid tumors in children.
