Metal-halide perovskites(MHPs)have emerged as a new class of semiconductors used in perovskite solar cells(PSCs)[1-5],perovskite light-emitting diodes(PeLEDs)[6-12],photo/X-ray detectors[13-16],and memristors[17,18].P...Metal-halide perovskites(MHPs)have emerged as a new class of semiconductors used in perovskite solar cells(PSCs)[1-5],perovskite light-emitting diodes(PeLEDs)[6-12],photo/X-ray detectors[13-16],and memristors[17,18].Pe LEDs can emit different light with high purity[19,20].展开更多
Inflammatory signaling and oxidative stress are two major components in the pathogenesis of alcoholic he-patitis.Alcohol consumption results in translocation of gut bacteria into the portal system along with lipopolys...Inflammatory signaling and oxidative stress are two major components in the pathogenesis of alcoholic he-patitis.Alcohol consumption results in translocation of gut bacteria into the portal system along with lipopolysaccharides that interact with toll-like receptors and results in the production of inflammatory and immunogenic mediators such as tumor necrosis factor-alpha(TNF-α) and interferons.Chronic consumption of alcohol causes priming of this process in which there is enhanced production of cytokines,interferon,interleukins,and TNF-α.Oxidative stress,genetic predisposition,and the unfolded protein response are other contributory mechanisms.Novel therapies aimed at these pathways may prevent,decrease,or delay the complications of alcoholic hepatitis.展开更多
Alcohol abuse and chronic hepatitis C virus(HCV)infection are two major causes of chronic liver disease in the United States.About 10%-15%of liver transplants performed in the United States are for patients with cirrh...Alcohol abuse and chronic hepatitis C virus(HCV)infection are two major causes of chronic liver disease in the United States.About 10%-15%of liver transplants performed in the United States are for patients with cirrhosis due to combined alcohol and HCV infection.Data on outcomes on graft and patient survival,HCV recurrence,and relapse of alcohol use comparing transplants in hepatitis C positive drinkers compared to alcohol abuse or hepatitis C alone are conflicting in the literature.Some studies report a slightly better overall outcome in patients who were transplanted for alcoholic cirrhosis vs those transplanted for HCV alone or for combined HCV and alcohol related cirrhosis.However,some other studies do not support these observations.However,most studies are limited to a retrospective design or small sample size.Larger prospective multicenter studies are needed to better define the outcomes in hepatitis C drinkers.展开更多
Elastic-plastic deformation behavior of austenitic, martensitic, and austenitic-martensitic high-Mn steels is investigated by using crystal plasticity theory. The development of expandable pipes made of two-phase stee...Elastic-plastic deformation behavior of austenitic, martensitic, and austenitic-martensitic high-Mn steels is investigated by using crystal plasticity theory. The development of expandable pipes made of two-phase steel for oil and gas well applications is needed for improved and efficient recovery of hydrocarbons from difficult reservoirs. The current research is aimed at improving the down-hole post-expansion material properties of expandable pipes. A mathematical model is first developed based on finite-deformation crystal plasticity theory assuming that slip is the prime mode of plastic deformation. The developed model is then numerically implemented by using the finite element software ABAQUS, through a user defined subroutine. Finite element simulations are performed for austenitic, martensitic, and austenitic-martensitic steels having different proportions of martensite in an austenite matrix. Three primary modes of loading are considered: uniaxial tension, compression and simple shear. The variation in yield strength, hardening pattern and dissipated energy is observed and analyzed.展开更多
The intercalation of metal is a promising method for the modulating electronic properties in transition metal dichalcogenides(TMDs).However,there still lacks enough knowledge about how the intercalated atoms directly ...The intercalation of metal is a promising method for the modulating electronic properties in transition metal dichalcogenides(TMDs).However,there still lacks enough knowledge about how the intercalated atoms directly impact the two-dimensional structural layers and modulate the band structures therein.Taking advantage of X-ray absorption fine structure and angle-resolved photoemission spectroscopy,we studied how Cu intercalation influences the host TaSe2 layers in Cu0.03TaSe2 crystals.The intercalated Cu atoms form bonds with Se of the host layers,and there is charge transfer from Cu to Se.By examining the changes of band dispersions,we show that the variation of electronic structures is beyond a simple rigid band model with merely charge doping effect.This work'reveals that the unusual change of band dispersions is associated with the formation of bonds between the intercalated metal elements and anion ions in the host layers,and provides a reference for the comprehensive understanding of the electronic structures in intercalated materials.展开更多
基金the National Natural Science Foundation of China (62234004,62175226)the National Natural Science Foundation of China (21961160720)+4 种基金the National Key Research and Development Program of China (2022YFA1204800)the University Synergy Innovation Program of Anhui Province (GXXT2022-009)the China Postdoctoral Science Foundation (2022M723006)the National Key Research and Development Program of China (2022YFB3803300)the open research fund of Songshan Lake Materials Laboratory (2021SLABFK02)。
文摘Metal-halide perovskites(MHPs)have emerged as a new class of semiconductors used in perovskite solar cells(PSCs)[1-5],perovskite light-emitting diodes(PeLEDs)[6-12],photo/X-ray detectors[13-16],and memristors[17,18].Pe LEDs can emit different light with high purity[19,20].
文摘Inflammatory signaling and oxidative stress are two major components in the pathogenesis of alcoholic he-patitis.Alcohol consumption results in translocation of gut bacteria into the portal system along with lipopolysaccharides that interact with toll-like receptors and results in the production of inflammatory and immunogenic mediators such as tumor necrosis factor-alpha(TNF-α) and interferons.Chronic consumption of alcohol causes priming of this process in which there is enhanced production of cytokines,interferon,interleukins,and TNF-α.Oxidative stress,genetic predisposition,and the unfolded protein response are other contributory mechanisms.Novel therapies aimed at these pathways may prevent,decrease,or delay the complications of alcoholic hepatitis.
文摘Alcohol abuse and chronic hepatitis C virus(HCV)infection are two major causes of chronic liver disease in the United States.About 10%-15%of liver transplants performed in the United States are for patients with cirrhosis due to combined alcohol and HCV infection.Data on outcomes on graft and patient survival,HCV recurrence,and relapse of alcohol use comparing transplants in hepatitis C positive drinkers compared to alcohol abuse or hepatitis C alone are conflicting in the literature.Some studies report a slightly better overall outcome in patients who were transplanted for alcoholic cirrhosis vs those transplanted for HCV alone or for combined HCV and alcohol related cirrhosis.However,some other studies do not support these observations.However,most studies are limited to a retrospective design or small sample size.Larger prospective multicenter studies are needed to better define the outcomes in hepatitis C drinkers.
文摘Elastic-plastic deformation behavior of austenitic, martensitic, and austenitic-martensitic high-Mn steels is investigated by using crystal plasticity theory. The development of expandable pipes made of two-phase steel for oil and gas well applications is needed for improved and efficient recovery of hydrocarbons from difficult reservoirs. The current research is aimed at improving the down-hole post-expansion material properties of expandable pipes. A mathematical model is first developed based on finite-deformation crystal plasticity theory assuming that slip is the prime mode of plastic deformation. The developed model is then numerically implemented by using the finite element software ABAQUS, through a user defined subroutine. Finite element simulations are performed for austenitic, martensitic, and austenitic-martensitic steels having different proportions of martensite in an austenite matrix. Three primary modes of loading are considered: uniaxial tension, compression and simple shear. The variation in yield strength, hardening pattern and dissipated energy is observed and analyzed.
基金We acknowledge the financial support from the National Key R&D Program of China(No.2017YFA0402901,2016YFA0401004)National Natural Science Foundation of China(No.11674296,21727801 and 11621063)+1 种基金the Key Research Program of the Chinese Academy of Sciences(No.XDPB01)the Innovative Program of Development Foundation of Hefei Center for Physical Science and Technology(No.2018CXFX002),NSFC-MAECI(51861135202).
文摘The intercalation of metal is a promising method for the modulating electronic properties in transition metal dichalcogenides(TMDs).However,there still lacks enough knowledge about how the intercalated atoms directly impact the two-dimensional structural layers and modulate the band structures therein.Taking advantage of X-ray absorption fine structure and angle-resolved photoemission spectroscopy,we studied how Cu intercalation influences the host TaSe2 layers in Cu0.03TaSe2 crystals.The intercalated Cu atoms form bonds with Se of the host layers,and there is charge transfer from Cu to Se.By examining the changes of band dispersions,we show that the variation of electronic structures is beyond a simple rigid band model with merely charge doping effect.This work'reveals that the unusual change of band dispersions is associated with the formation of bonds between the intercalated metal elements and anion ions in the host layers,and provides a reference for the comprehensive understanding of the electronic structures in intercalated materials.