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应用卡巴拉汀治疗轻到中重度阿尔茨海默病患者52周有效性研究(译文) 被引量:1
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作者 Martin Farlow ravi anand +3 位作者 John Messina Jr Richard Hartman Jeffrey Veach 《中国神经免疫学和神经病学杂志》 CAS 2002年第2期122-124,共3页
卡巴拉汀酒石酸盐 ( ENA71 3,艾斯能 )是具有中枢活性的胆碱酯酶抑制剂。通过为期 2 6周、双盲、安慰剂对照研究后 ,又进行了为期 2 6周的开放标记扩展临床研究 ,以评估其治疗轻到中重度阿尔茨海默病的有效性。结果表明 ,服用卡巴拉汀 6... 卡巴拉汀酒石酸盐 ( ENA71 3,艾斯能 )是具有中枢活性的胆碱酯酶抑制剂。通过为期 2 6周、双盲、安慰剂对照研究后 ,又进行了为期 2 6周的开放标记扩展临床研究 ,以评估其治疗轻到中重度阿尔茨海默病的有效性。结果表明 ,服用卡巴拉汀 6~ 1 2 mg/d共 5 2周的患者 ,认知功能明显好于以前服用安慰剂者。 展开更多
关键词 胆碱酯酶抑制剂 卡巴接湘 临床试验 阿尔茨海默病 治疗
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Differential fault location identification by machine learning
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作者 Anubhab Baksi Santanu Sarkar +2 位作者 Akhilesh Siddhanti ravi anand Anupam Chattopadhyay 《CAAI Transactions on Intelligence Technology》 EI 2021年第1期17-24,共8页
As the fault‐based attacks are becoming a more pertinent threat in today's era of edge computing/internet‐of‐things,there is a need to streamline the existing tools for better accuracy and ease of use,so that w... As the fault‐based attacks are becoming a more pertinent threat in today's era of edge computing/internet‐of‐things,there is a need to streamline the existing tools for better accuracy and ease of use,so that we can gauge the attacker's power and a proper countermeasure can be devised in the long run.In this regard,we propose a machine learning(ML)assisted tool that can be used in the context of a differential fault attack.In particular,finding the exact fault location by analysing the output difference(typically the XOR of the nonfaulty and the faulty ciphertexts)is somewhat nontrivial.During the literature survey,we notice that the Pearson's correlation coefficient dominantly is used for this purpose,and has almost become the defacto standard.While this method can yield good accuracy for certain cases,we argue that an MLbased method is more powerful in all the situations we experiment with.We sub-stantiate our claim by showing the relative performances(we choose the commonly used multilayer perceptron as our ML tool)with two variants of Grain‐128a(a stream cipher,and a stream cipher with authentication),the lightweight stream cipher LIZARD and the lightweight block cipher SIMON‐32(where the faults are injected at the fifth last rounds).Our results demonstrate that a common ML tool can outperform the correlation with the same training/testing data.We believe that our work extends the state‐of‐the‐art by showing how traditional cryptographic methods can be replaced by a more powerful ML tool. 展开更多
关键词 FAULT typically GAUGE
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