The high frequency decay parameter κ has been considered as one of the important parameters required in the simulation of earthquake strong ground motions necessary for the proper evaluation of seismic hazard of a re...The high frequency decay parameter κ has been considered as one of the important parameters required in the simulation of earthquake strong ground motions necessary for the proper evaluation of seismic hazard of a region. The present study estimated “κ” for the highly seismic active region of North East India. The spectral analysis of 598 accelerograms of 32 earthquakes has been done using [1] approach for this purpose. The average values of “κ” have been found to be 0.049, 0.047 and 0.040 for L-, T- and V-component respectively. The distance dependence of κ is not significant in the region. The κ 0 (κ at R = 0) for soft rock stations is found to be more than those of hard rock sites in consistent with other similar studies. The correlation between “κ” and earthquake magnitude at most of the stations for the region under study is not significant which indicates that κ depends on the site conditions in the region. The κ values estimated in the present study are useful for the evaluation of seismic hazard of the region.展开更多
Heat shock proteins (Hsps) or molecular chaperones, are highly conserved protein families present in allstudied organisms. Following cellular stress, the intracellular concentration of Hsps generally increases several...Heat shock proteins (Hsps) or molecular chaperones, are highly conserved protein families present in allstudied organisms. Following cellular stress, the intracellular concentration of Hsps generally increases several folds.Hsps undergo ATP-driven conformational changes to stabilize unfolded proteins or unfold them for translocationacross membranes or mark them for degradation. They are broadly classified in several families according to theirmolecular weights and functional properties. Extensive studies during the past few decades suggest that Hsps play avital role in both normal cellular homeostasis and stress response. Hsps have been reported to interact with numeroussubstrates and are involved in many biological functions such as cellular communication, immune response, proteintransport, apoptosis, cell cycle regulation, gametogenesis and aging. The present review attempts to provide a briefoverview of various Hsps and summarizes their involvement in diverse biological activities.展开更多
文摘The high frequency decay parameter κ has been considered as one of the important parameters required in the simulation of earthquake strong ground motions necessary for the proper evaluation of seismic hazard of a region. The present study estimated “κ” for the highly seismic active region of North East India. The spectral analysis of 598 accelerograms of 32 earthquakes has been done using [1] approach for this purpose. The average values of “κ” have been found to be 0.049, 0.047 and 0.040 for L-, T- and V-component respectively. The distance dependence of κ is not significant in the region. The κ 0 (κ at R = 0) for soft rock stations is found to be more than those of hard rock sites in consistent with other similar studies. The correlation between “κ” and earthquake magnitude at most of the stations for the region under study is not significant which indicates that κ depends on the site conditions in the region. The κ values estimated in the present study are useful for the evaluation of seismic hazard of the region.
基金Department of Biotechnology(DBT),Department of Science and Technology(DST),New Delhi and Delhi University Research and Development Grant to SS.DST-BOYSCAST fellowship to SS is also gratefully acknowledged.
文摘Heat shock proteins (Hsps) or molecular chaperones, are highly conserved protein families present in allstudied organisms. Following cellular stress, the intracellular concentration of Hsps generally increases several folds.Hsps undergo ATP-driven conformational changes to stabilize unfolded proteins or unfold them for translocationacross membranes or mark them for degradation. They are broadly classified in several families according to theirmolecular weights and functional properties. Extensive studies during the past few decades suggest that Hsps play avital role in both normal cellular homeostasis and stress response. Hsps have been reported to interact with numeroussubstrates and are involved in many biological functions such as cellular communication, immune response, proteintransport, apoptosis, cell cycle regulation, gametogenesis and aging. The present review attempts to provide a briefoverview of various Hsps and summarizes their involvement in diverse biological activities.
