Safety of hydroimplantation in cataract surgery in patients with pseudoexfoliation syndrome

AIM：To evaluate the safety of hydroimplantation in cataract surgery in patients with pseudoexfoliation syndrome.METHODS：This prospective randomized study comprised 100 eyes of 100 consecutive patients who underwent cataract surgery and implantation of foldable intraocular lens（IOL）. Each eye was assigned to group 1 or group 2. Hydroimplantation without using viscoelastic agent as group 1（n=50）, and hydroxypropylmethylcellulose（Eyevisc, Biotech, India） was used in group 2（n=50）. RESULTS：There were no statistically significant differences in central corneal thickness（CCT） and corneal endothelial cell count（ECC） between both groups at each visit and percentage change in CCT and ECC（P〉0.05）. The mean intraocular pressure（IOP） at postoperative 5h increased statistically significantly in group 2（P〈0.001）. There was no statistically significant difference in IOP between two groups, before and after surgery excluding the 24 h postoperative IOP, but patients in group 2 had higher IOP than that in the group 1 at 24 h after surgery（P=0.035）. No case in either group experienced posterior capsular rupture, or zonular dialysis. Fixation of the globe during IOL implantation was better in group 1 than that in group 2.CONCLUSION：Hydroimplantation has advantages in terms of IOP changes and duration of the surgery and seems to be safe in patients with pseudoexfoliation syndrome.

Effect of 1%brinzolamide and 0.5%timolol fixed combination on intraocular pressure after cataract surgery with phacoemulsification

AIM:To evaluate the effect of brinzolamide-timolol fixed combination on intraocular pressure(IOP)after cataract surgery.METHODS:The study included 92 eyes of 87 patients who underwent cataract surgery and intraocular lens implantation.Patients scheduled for phacoemulsification were assigned to 1 of 2 groups.The treatment group received 1 drop of brinzolamide-timolol fixed combination immediately after surgery,and the control group received no treatment.The IOP was measured preoperatively and at 2h and 24h postoperatively.RESULTS:The mean IOP change was lower in the treatment group than in the control group at 2h postoperatively.The difference between the mean IOP values of the two groups at 2h postoperatively was found to be statistically significant.Twenty-four hours after the surgery,the mean IOP change was still higher in the control group when compared to the treatment group.CONCLUSION:The fixed combination brinzolamidetimolol can effectively reduce IOP after cataract surgery.