AIM：To estimate the overall prevalence of diabetic retinopathy（DR） in Iran by a systematic review and Metaanalysis.METHODS：We conducted a search of all published literature on diabetic patients for the prevalence ...AIM：To estimate the overall prevalence of diabetic retinopathy（DR） in Iran by a systematic review and Metaanalysis.METHODS：We conducted a search of all published literature on diabetic patients for the prevalence of DR using Web of Sciences, Pub Med, Scopus, Google Scholar, and national electronic databases SID, Magiran, and Iranmedex from their inception until September 2016 with standard keywords. Pooled estimates of the DR prevalence and the corresponding 95% confidence intervals（CI） were calculated using random effects models.RESULTS：Thirty-one studies involving 23 729 patients with type Ⅰ and Ⅱ diabetes were included. The publication bias assumption for prevalence of DR was rejected by Begg and Egger tests（P=0.825, P=0.057, respectively）. The results of Cochran test and I^2 statistics showed considerable heterogeneity for prevalence of DR（Q=1278.21, d.f.=30, P〈0.001 and I^2=97.7%）. The prevalence of DR, non-proliferative diabetic retinopathy（NPDR） and proliferative diabetic retinopathy（PDR） in Iranian diabetic patients were 41.9%（95% CI：35.6-48.2）, 32.2%（95% CI：28.7-35.8）, and 13.2%（95% CI：8.3-18.1）, respectively. CONCLUSION：The prevalence of DR in Iran appears a little high. NPDR was more common. This study highlights the necessity for DR screening and management in diabetic patients in Iran.展开更多
AIM： To estimate overall prevalence of retinopathy of prematurity （ROP） in Iran using a systematic review and Meta-analysis. METHODS： A systematic review and Meta-analysis was performed of all published studies p...AIM： To estimate overall prevalence of retinopathy of prematurity （ROP） in Iran using a systematic review and Meta-analysis. METHODS： A systematic review and Meta-analysis was performed of all published studies pertaining to prevalence of ROP using international and national electronic databases （ISI Web of Sciences, PubMed, Scopus, Google Scholar, SlD, Maglran, and IranMedex） from their inception until May 2016 with standard keywords. Begg and Egger tests were used to examine the publication bias and Cochran test and f statistics were used to evaluate the statistical heterogeneity. Pooled estimate of the prevalence of ROP were calculated using random effects Meta- analysis. RESULTS： The publication bias assumption was rejected by Egger tests with P-value equal to 0.024. The results of Cochran test and 12 statistics revealed substantial heterogeneity （Q=1099.02, df=25, f=97.7%, P=-0.001）. The overall prevalence of ROP using the random effect model in Iran was 26.1% （95% Ch 20.3%-31.8%）. CONCLUSION： The prevalence of ROP is relatively high in Iran. Low birth weight and gestational age are significant risk factors for the disease. Improved care, including oxygen delivery and monitoring, for preterm babies in all facility settings would reduce the number of babies affected with ROP.展开更多
文摘AIM：To estimate the overall prevalence of diabetic retinopathy（DR） in Iran by a systematic review and Metaanalysis.METHODS：We conducted a search of all published literature on diabetic patients for the prevalence of DR using Web of Sciences, Pub Med, Scopus, Google Scholar, and national electronic databases SID, Magiran, and Iranmedex from their inception until September 2016 with standard keywords. Pooled estimates of the DR prevalence and the corresponding 95% confidence intervals（CI） were calculated using random effects models.RESULTS：Thirty-one studies involving 23 729 patients with type Ⅰ and Ⅱ diabetes were included. The publication bias assumption for prevalence of DR was rejected by Begg and Egger tests（P=0.825, P=0.057, respectively）. The results of Cochran test and I^2 statistics showed considerable heterogeneity for prevalence of DR（Q=1278.21, d.f.=30, P〈0.001 and I^2=97.7%）. The prevalence of DR, non-proliferative diabetic retinopathy（NPDR） and proliferative diabetic retinopathy（PDR） in Iranian diabetic patients were 41.9%（95% CI：35.6-48.2）, 32.2%（95% CI：28.7-35.8）, and 13.2%（95% CI：8.3-18.1）, respectively. CONCLUSION：The prevalence of DR in Iran appears a little high. NPDR was more common. This study highlights the necessity for DR screening and management in diabetic patients in Iran.
文摘AIM： To estimate overall prevalence of retinopathy of prematurity （ROP） in Iran using a systematic review and Meta-analysis. METHODS： A systematic review and Meta-analysis was performed of all published studies pertaining to prevalence of ROP using international and national electronic databases （ISI Web of Sciences, PubMed, Scopus, Google Scholar, SlD, Maglran, and IranMedex） from their inception until May 2016 with standard keywords. Begg and Egger tests were used to examine the publication bias and Cochran test and f statistics were used to evaluate the statistical heterogeneity. Pooled estimate of the prevalence of ROP were calculated using random effects Meta- analysis. RESULTS： The publication bias assumption was rejected by Egger tests with P-value equal to 0.024. The results of Cochran test and 12 statistics revealed substantial heterogeneity （Q=1099.02, df=25, f=97.7%, P=-0.001）. The overall prevalence of ROP using the random effect model in Iran was 26.1% （95% Ch 20.3%-31.8%）. CONCLUSION： The prevalence of ROP is relatively high in Iran. Low birth weight and gestational age are significant risk factors for the disease. Improved care, including oxygen delivery and monitoring, for preterm babies in all facility settings would reduce the number of babies affected with ROP.
