Aim:Many therapeutic means have emerged to treat esophageal cancer.Factors relating to nutritional status such as body weight maintenance are important to the continuation of these treatments.In this study,we investig...Aim:Many therapeutic means have emerged to treat esophageal cancer.Factors relating to nutritional status such as body weight maintenance are important to the continuation of these treatments.In this study,we investigated methods to extend the administration of diversified treatments for patients with esophageal cancer,especially regarding measures to suppress body weight loss after surgery.Methods:We retrospectively evaluated a strategy for preventing postoperative body weight loss which can hinder the continuation of treatment via a reconstruction method aimed at safety and comfort combined with postoperative dietary intake and nutritional support for esophageal cancer patients.Results:The subjects comprised 386 patients who underwent subtotal stomach reconstruction during esophageal cancer surgery performed from January 2008 to January 2021 at Gifu University Hospital.The anastomotic leakage rate was 0.5%.By administering oral nutritional supplementation under strict rules using ENSURE®H during the perioperative period,the percentage of body weight loss after 5 years could be limited to 4.78%compared to that before treatment.Scores assessing early feeling of fullness measured using the EORTC QLQ-OES18 at postoperative months 3,12,24,36,48,and 60 were 1.7±0.3,2.0±0.2,1.2±0.3,1.3±0.2,1.5±0.2,and 1.4±0.1,respectively.Conclusion:Considering methods to eliminate the factors that prevent continuation of treatment may lead to sustainable treatment against esophageal cancer.Proper surgical reconstruction and nutritional management will allow maintenance of body weight and good quality of life.展开更多
文摘Aim:Many therapeutic means have emerged to treat esophageal cancer.Factors relating to nutritional status such as body weight maintenance are important to the continuation of these treatments.In this study,we investigated methods to extend the administration of diversified treatments for patients with esophageal cancer,especially regarding measures to suppress body weight loss after surgery.Methods:We retrospectively evaluated a strategy for preventing postoperative body weight loss which can hinder the continuation of treatment via a reconstruction method aimed at safety and comfort combined with postoperative dietary intake and nutritional support for esophageal cancer patients.Results:The subjects comprised 386 patients who underwent subtotal stomach reconstruction during esophageal cancer surgery performed from January 2008 to January 2021 at Gifu University Hospital.The anastomotic leakage rate was 0.5%.By administering oral nutritional supplementation under strict rules using ENSURE®H during the perioperative period,the percentage of body weight loss after 5 years could be limited to 4.78%compared to that before treatment.Scores assessing early feeling of fullness measured using the EORTC QLQ-OES18 at postoperative months 3,12,24,36,48,and 60 were 1.7±0.3,2.0±0.2,1.2±0.3,1.3±0.2,1.5±0.2,and 1.4±0.1,respectively.Conclusion:Considering methods to eliminate the factors that prevent continuation of treatment may lead to sustainable treatment against esophageal cancer.Proper surgical reconstruction and nutritional management will allow maintenance of body weight and good quality of life.
