The aim of this work was to validate a wet mixing process, in which a liquid spray is used to impregnate particles during mixing. The experimental results obtained using a bladed-mixer with a near-infrared sensor were...The aim of this work was to validate a wet mixing process, in which a liquid spray is used to impregnate particles during mixing. The experimental results obtained using a bladed-mixer with a near-infrared sensor were compared with the results obtained using a 1 : 1 discrete element method simulation. The porous particles used in both cases absorbed the sprayed liquid for a process time of about 18 min. Mul- tiple sensors attached to the mixer wall continuously monitored the liquid contents of passing particles. The sensors were modeled in the simulation and the resulting signals were analyzed and compared with the experimental results. We show that the algorithms used for spray and liquid absorption can be used to predict the moisture distribution inside granular materials in chemical and pharmaceutical processes. Such simulations can help to save money, e.g., in resource-intensive experimental plans and equipment design studies, and by varying material parameters.展开更多
文摘The aim of this work was to validate a wet mixing process, in which a liquid spray is used to impregnate particles during mixing. The experimental results obtained using a bladed-mixer with a near-infrared sensor were compared with the results obtained using a 1 : 1 discrete element method simulation. The porous particles used in both cases absorbed the sprayed liquid for a process time of about 18 min. Mul- tiple sensors attached to the mixer wall continuously monitored the liquid contents of passing particles. The sensors were modeled in the simulation and the resulting signals were analyzed and compared with the experimental results. We show that the algorithms used for spray and liquid absorption can be used to predict the moisture distribution inside granular materials in chemical and pharmaceutical processes. Such simulations can help to save money, e.g., in resource-intensive experimental plans and equipment design studies, and by varying material parameters.