Combined with the optical beam deflection,a novel approach of phase matched broadband scanning optical parametric chirped pulse amplification(OPCPA)was proposed.For this scheme,there was no superfluous operations to t...Combined with the optical beam deflection,a novel approach of phase matched broadband scanning optical parametric chirped pulse amplification(OPCPA)was proposed.For this scheme,there was no superfluous operations to the chirped signal pulse which propagated in a changeless direction straightforward,but the pump beam were deflected in space with time by passing through a KTN crystal,which was applied with varied driving voltage.The theories of phase matching of each chirped signal frequency based on pump beam deflection was analyzed detailedly.And the type-I amplification of chirped signal with 800 nm central wavelength and 20 nm bandwidth pumped by 532 nm in BBO crystal was simulated as a case in point.The simulation results showed that the spectral distribution of chirped signal pulse was almost the same as the initial form,i.e.,there was nearly no narrowing on the amplified spectrum by using of the scanning OPCPA based on pump beam deflection.In addition,the simulations demonstrated that it was worth minimizing the voltage deviation applied to KTN crystal as much as possible for the sake of better waveform,larger bandwidth and higher conversion efficiency of amplified signal pulse in the proposed scanning OPCPA.展开更多
Objective:The aim of our study was to analyze hepatic dysfunction and failure after hepatocellular carcinoma (HCC) resection and relationship of clinical and pathological factors.Methods:Clinical and pathological data...Objective:The aim of our study was to analyze hepatic dysfunction and failure after hepatocellular carcinoma (HCC) resection and relationship of clinical and pathological factors.Methods:Clinical and pathological data of 467 HCC patients was retrospectively reviewed,who underwent liver resection from January 2002 to December 2008 in the Affiliated Hospital of Medical College,Qingdao University,and the post-resectional liver dysfunction and failure risk factors were analyzed by univariate and multivariate analysis.Results:The morbidity of post-resectional liver dysfunction and failure was 1.7% and 2.1%.The post-resectional liver dysfunction and failure after HCC hepatectomy into the statistical analysis:univariate analysis revealed preoperative platelet level (<100×109/L),serum albumin level (<35 g/L),serum gamma-Glutamyl transferase (> 64 U/L),Child-Pugh classification (B),MELD score (≥9),intraoperative bleeding (≥1000 mL),blood transfusion were positive factors,multivariate analysis (Logistic) revealed that preoperative platelet level (0.983,95% CI=0.971-0.995) and intraoperative blood transfusion (3.145,95% CI=1.027-12.028) were independent risk factors for post-resectional liver dysfunction and failure.Conclusion:Prevented liver failure and liver dysfunction occurring after liver resection,it is the key to accurate preoperative assessment of liver function and the patient's reserved liver functional,precise hepatectomy and reasonable blockage of hepatic inflow.展开更多
基金supported by Science and Technology Innovation Seedling Project of Sichuan Province,China(Grant No.2018100)Major Project of CDNU(Grant No.CS18ZDZ0511).
文摘Combined with the optical beam deflection,a novel approach of phase matched broadband scanning optical parametric chirped pulse amplification(OPCPA)was proposed.For this scheme,there was no superfluous operations to the chirped signal pulse which propagated in a changeless direction straightforward,but the pump beam were deflected in space with time by passing through a KTN crystal,which was applied with varied driving voltage.The theories of phase matching of each chirped signal frequency based on pump beam deflection was analyzed detailedly.And the type-I amplification of chirped signal with 800 nm central wavelength and 20 nm bandwidth pumped by 532 nm in BBO crystal was simulated as a case in point.The simulation results showed that the spectral distribution of chirped signal pulse was almost the same as the initial form,i.e.,there was nearly no narrowing on the amplified spectrum by using of the scanning OPCPA based on pump beam deflection.In addition,the simulations demonstrated that it was worth minimizing the voltage deviation applied to KTN crystal as much as possible for the sake of better waveform,larger bandwidth and higher conversion efficiency of amplified signal pulse in the proposed scanning OPCPA.
文摘Objective:The aim of our study was to analyze hepatic dysfunction and failure after hepatocellular carcinoma (HCC) resection and relationship of clinical and pathological factors.Methods:Clinical and pathological data of 467 HCC patients was retrospectively reviewed,who underwent liver resection from January 2002 to December 2008 in the Affiliated Hospital of Medical College,Qingdao University,and the post-resectional liver dysfunction and failure risk factors were analyzed by univariate and multivariate analysis.Results:The morbidity of post-resectional liver dysfunction and failure was 1.7% and 2.1%.The post-resectional liver dysfunction and failure after HCC hepatectomy into the statistical analysis:univariate analysis revealed preoperative platelet level (<100×109/L),serum albumin level (<35 g/L),serum gamma-Glutamyl transferase (> 64 U/L),Child-Pugh classification (B),MELD score (≥9),intraoperative bleeding (≥1000 mL),blood transfusion were positive factors,multivariate analysis (Logistic) revealed that preoperative platelet level (0.983,95% CI=0.971-0.995) and intraoperative blood transfusion (3.145,95% CI=1.027-12.028) were independent risk factors for post-resectional liver dysfunction and failure.Conclusion:Prevented liver failure and liver dysfunction occurring after liver resection,it is the key to accurate preoperative assessment of liver function and the patient's reserved liver functional,precise hepatectomy and reasonable blockage of hepatic inflow.
