基于Bi-LSTM的在线物联网设备识别方法

为了提高在线物联网设备识别准确率和识别粒度,提出一种基于Bi-LSTM的在线物联网设备识别方法,通过探测目标端口获取响应报文,经分词处理后利用二阶段算法模型精准识别设备型号。第一阶段利用TF-IDF算法剔除应用层低权重报文字段,得到应用层指纹,并利用Bi-LSTM神经网络能够捕获长远上下文信息的优点,提取指纹深层次特征识别设备厂商;第二阶段建立型号知识库,采用Jaro-Winkler文本相似度匹配算法识别型号和设备类型,通过设备厂商精准判别设备型号,达到在线物联网设备识别的目的。结果表明:方法整体准确率为98.8%,召回率为96.5%,与传统的流量指纹加机器学习识别方式相比平均准确率高出4.7%,识别设备型号覆盖率达到97%,细化了在线物联网设备识别粒度。该方法有助于同型号物联网设备与漏洞做更精准的关联匹配,在漏洞爆发时及时制定相应的防护措施。

工装篮烘干筒内硅料颗粒混合过程的数值模拟

硅料的烘干是全自动超声波清洗机在生产过程中最重要的环节,研究该环节工装篮烘干筒内硅料颗粒的烘干过程对烘干装置节能和工装篮烘干筒结构优化具有重要意义。通过DEM离散软件,在搅棒形状、搅棒数、烘干筒外框转速、颗粒状硅料填充率等影响因素下对工装篮烘干筒内颗粒状硅料的混合过程进行数值模拟和分析。通过单因素和多因素正交实验模拟及Lacey指数M对混合均匀性进行定量分析,得到各参数最佳工况。结果表明:与其他形状的搅棒相比,长方体搅棒的烘干筒内颗粒混合效果最好;当搅棒数为6时,混合程度达到最佳值,颗粒群混合效果随着填充率的增加而下降。与填充率为31.73%和41.40%相比,填充率为23.60%时对流混合作用影响最强,混合效果更好。烘干筒转速为8.91 rad/s时,可以提高硅料颗粒混合的均匀性和质量,从而提高混合效率。通过正交分析得出,影响因素中烘干筒外框转速影响最大,其次为颗粒填充率、搅棒数、搅棒形状。

消化道症状为主的广泛性焦虑障碍患者胃镜成像诊断特点

目的探讨消化道症状为主的广泛性焦虑障碍(GAD)患者胃镜成像诊断特点。方法将该院收治的有消化道症状的GAD患者60例作为A组,有消化道症状的非GAD患者60例作为B组,分别对其进行胃镜和病理检查。结果两组胃镜成像诊断特点明显不同,A组慢性非萎缩性胃炎95.00%明显高于B组30.00%,差异有统计学意义(P<0.05);两组病理检查结果相似,A组淋巴细胞和浆细胞浸润98.33%与B组90.00%接近,差异无统计学意义(P>0.05)。结论消化道症状为主的GAD患者,胃镜成像诊断以慢性非萎缩性胃炎为主,胃黏膜局部充血、隆起或充血不明显;病理检查提示不伴有胃黏膜萎缩,以慢性炎症细胞浸润为主。

The Modulatory Effect of Dietary Apostichopus japonicus on Mice with Ulcerative Colitis Induced by Trinitrobenzene Sulfonic Acid

Sea cucumber is a food with nutritional benefits distributing mainly in Asia, and Apostichopus japonicus (A. japonicus) is a kind of sea cucumber whose quality is better than any others. However, different processing methods make various effect on its quality. In this study, we evaluated the protection effect of A. japonicus with different processing methods on mice with ulcerative colitis induced by trinitrobenzene sulfonic acid (TNBS), especially on the intestinal microflora. The expression of IFN-γ/IL-4 and IL-1β in gut, and intestinal microbiota were discussed. The results revealed that three different processing methods of A. japonicus could decrease the expression of inflammatory cytokines, except for the expression of IFN-γ/IL-4 treated with enzymatic, and dried A. japonicus was the most efficient. A. japonicus could change the microbiotic imblance relatively back to normal in terms of bacterial diversity and composition, meanwhile increase the abundance of Bifidobacteria, Lactobacillus and Clostridium leptum. The elements of protein, polysaccharide in dried, instant, enzymatic A. japonicus are 73.09%, 65.06%, 57.42% and 6.72%, 5.46%, 5.45% respectively. This study indicated that A. japonicus have a good improving effect on ulcerative colitis, especially on the microbiome, and processing methods had an effect on alleviation of ulcerative colitis, which might be associated with content of protein and polysaccharide.

The Preventative Effect of Dietary Apostichopus japonicus on Intestinal Microflora Dysregulation in Immunosuppressive Mice Induced by Cyclophosphamide

Sea cucumbers are recognized as food and drug resources with many nutritional benefits, and Apostichopus japonicus is a kind of sea cucumber with good quality. Processing methods have some effect on its quality. This study aimed to explore the effects of Apostichopus japonicus with three different processing methods (dried, instant, and enzymatic sea cucummbers) on intestinal microflora dysregulation using a cyclophosphamide (cy) induced immunosuppressive mouse model. The expression of lysozyme, immunoglobulin A (IgA), and polymeric immunoglobulin receptor (pIgR) in the intestine and gut microbiota were investigated. The results showed that three types of A. japonicus could improve mucosal immunity and regulate gut microbiota. Dietary A. japonicus could reverse microbial imbalance, including increasing the bacterial diversity, enhancing the number of Bifidobacterium, and changing the bacterial composition. The most effect was observed with dried A. japonicus. Expression of lysozyme and IgA in the intestine was significantly increased. This study identified positive effects of dietary A. japonicus on mucosal immunity, particularly on gut microbiota, suggesting that dietary A. japonicus may aid in improving mucosal immunity and preventing exogenous infection. Additionally, the processing method has some effect on immunomodulatory function.

催化剂催化二氧化硫共聚的研究进展

目前有关二氧化硫(SO2)减排技术的研究成熟且较多,而SO2的高效利用却研究较少。SO2与烯烃、环氧化物及其他单体共聚制备含硫高分子是利用SO2的有效途径。探索和开发新型高效催化剂是提高其共聚反应效率及调控共聚物结构的根本手段和方法,因此,高效催化剂成为该领域的研究重点。文中分析比较了有机金属、过氧化物、Lewis酸、Lewis碱等催化剂对SO2与单体共聚制备含硫高分子的影响规律,希望对SO2催化共聚的研究和发展提供参考。

Elevation gradient distribution of indices of tree population in a montane forest:The role of leaf traits and the environment

Background:To disentangle the controls on species distribution in the context of climate change is a central element in proposed strategies to maintain species diversity.However,previous studies have focused mainly on the roles of abiotic factors(e.g.,climate and soil properties),with much less attention given to the roles of biotic factors such as functional traits.Here,we measured eight leaf traits for 240 individual trees of 53 species and analyzed the variation in traits and population composition indices and their relationships with soil properties,climate factors,and leaf traits.Results:The tree density,frequency and species importance values of the overall species and saplings significantly increased with increasing elevation,while the same indices(except for species frequency)of adults did not significantly change.The largest percentage of variation of species importance value(greater than 50%)was explained by climate,but leaf traits played a critical role in driving elevation distribution patterns of both saplings and adults;the abundance of saplings significantly increased with elevation,with increased leaf carbon contents,while the abundance of adults did not change in accordance with a nutrient conservation strategy associated with the leaf economic spectrum.Conclusions:Our results suggest that the elevation gradient distribution of woody plant species is dependent on tree size and that local atmospheric humidity and leaf traits cause considerable variation in species distribution along subtropical mountain elevations.We provide evidence of which leaf traits play a key role in the elevation gradient distribution of different sizes of woody tree species.

对医疗质量评价指标体系的评析

医疗质量评价体系是统计学方法为基础工具,可对医疗服务水平进行整体评价。能够有效反映医院医疗质量与特征的总体水平。本文从该指标体系的涵盖广度出发,从其性质、来源与用途3个方面对医疗质量评价体系进行了详细的分类界定,并从指标的收集利用与今后的发展趋势方面剖析了该体系在现阶段所存在的一些问题与隐性缺陷。

固相萃取-气相色谱法测定水中硝基氯苯类化合物

建立固相萃取-气相色谱法测定水中15种硝基氯苯类化合物的方法。选用HLB柱为固相萃取柱,选用环己烷∶丙酮(3∶1,V∶V)混合溶剂作洗脱剂,得到方法检出限为0.011～0.040μg/L。空白水样加标回收率为73.6%～119%,相对标准偏差为6.1%～13.9%,精密度和准确度良好。对成分不复杂的实际水样进行测定,加标回收率为64.1%～118%,相对标准偏差为5.8%～15.6%,该方法能够基本满足成分不复杂的环境水体中痕量硝基氯苯类化合物的测定。

无人机遥感技术在环境监测的应用研究

传统的监测方法在某种程度上已经不太适应新形势下的环境监测工作,当前急需一种新的监测技术进行补充。本文以无人机遥感技术为例,讨论无人机遥感技术在环境监测方面的应用。无人机遥感技术以其快速、经济、安全和灵活等优势,广泛应用于大气环境监测、水环境监测、生态环境监测等领域,已经成为国内外学者研究的热点。

Discrepancies in Simulated Ocean Net Surface Heat Fluxes over the North Atlantic

The change in ocean net surface heat flux plays an important role in the climate system.It is closely related to the ocean heat content change and ocean heat transport,particularly over the North Atlantic,where the ocean loses heat to the atmosphere,affecting the AMOC(Atlantic Meridional Overturning Circulation)variability and hence the global climate.However,the difference between simulated surface heat fluxes is still large due to poorly represented dynamical processes involving multiscale interactions in model simulations.In order to explain the discrepancy of the surface heat flux over the North Atlantic,datasets from nineteen AMIP6 and eight highresSST-present climate model simulations are analyzed and compared with the DEEPC(Diagnosing Earth's Energy Pathways in the Climate system)product.As an indirect check of the ocean surface heat flux,the oceanic heat transport inferred from the combination of the ocean surface heat flux,sea ice,and ocean heat content tendency is compared with the RAPID(Rapid Climate Change-Meridional Overturning Circulation and Heat flux array)observations at 26°N in the Atlantic.The AMIP6 simulations show lower inferred heat transport due to less heat loss to the atmosphere.The heat loss from the AMIP6 ensemble mean north of 26°N in the Atlantic is about10 W m–2 less than DEEPC,and the heat transport is about 0.30 PW(1 PW=1015 W)lower than RAPID and DEEPC.The model horizontal resolution effect on the discrepancy is also investigated.Results show that by increasing the resolution,both surface heat flux north of 26°N and heat transport at 26°N in the Atlantic can be improved.

Synthesis and in Vitro Cytotoxicity of a Novel Conjugate of Polyamide and Phospholipid

In order to increase the cell penetration and decrease the cytotoxicity of the synthetic molecule, we designed and synthesized a DNA-binding ligand, which was a conjugate of polyamide and phospholipid. We examined the differences in the effect on cytotoxicity between the conjugate and the native polyamide. As expected that the in vitro cytotoxicity of the conjugate was obviously lower than that of the native polyamide either in HeLa cells or SH-SY5Y neuroblastoma cells.

Application of ICT in Art Education： A Case Study of HIFA

This paper intends to expound the application of information and communication technology （ICT） in art education, making a case of study of Hubei Institute of Fine Arts （HIFA）. Despite financial pressure, HIFA has invested heavily in the infi＇aslructure. The classrooms at HIFA can be roughly divided into three kinds： studios, multimedia classrooms and computer labs with reference to ICT. There are three general approaches to the instructional use of the technology at HIFA, namely： learning about computers and the Intemet; learning with computers and the Intemet and learning through computers and the Internet. The utilization oflCT has shaped the art education model of HIFA considerably and has brought about a lot of changes and benefits to the faculty and students. However, its disadvantage may overweigh the advantage unless it is properly harnessed.

In situ self-assembly of amphiphilic dextran micelles and superparamagnetic iron oxide nanoparticle-loading as magnetic resonance imaging contrast agents

Polymeric micelles have long been considered as promising nanocarrier for hydrophobic drugs and imaging probes,due to their nanoscale particle size,biocompatibility and ability to loading reasonable amount of cargoes.Herein,a facile method for dextran micelles preparation was developed and their performance as carriers of superparamagnetic iron oxide(SPIO)nanocrystals was evaluated.Amphiphilic dextran(Dex-g-OA)was synthesized via the Schiff base reactions between oxidized dextran and oleylamine,and self-assembled in situ into nano-size micelles in the reaction systems.The self-assembling behaviors of the amphiphilic dextran were identified using fluorescence resonance energy transfer technique by detection the energy transfer signal between the fluorophore pairs,Cy5 and Cy5.5.Hydrophobic SPIO nanoparticles(Fe_(3)O_(4)NPs)were successfully loaded into the dextran micelles via the in situ self-assembly process,leading to a series of Fe_(3)O_(4)NPs-loaded micelle nanocomposites(Fe_(3)O_(4)@Dex-g-OA)with good biocompatibility,superparamagnetism and strongly enhanced T_(2)relaxivity.At the magnetic field of 0.5 T,the Fe_(3)O_(4)@Dex-g-OA nanocomposite with particle size of 116.2±53.7 nm presented a higher T_(2)relaxivity of 327.9 mM_(re)^(-1)·s^(-1)·s^(−1).The prepared magnetic nanocomposites hold the promise to be used as contrast agents in magnetic resonance imaging.

对新型烟草制品征收消费税的国际经验与政策建议

近年来,新型烟草制品在全球发展迅速,对新型烟草制品征税的合理性、税制设计的适当性和现实征管的可行性对消费税的征收提出了新的挑战。本文阐述了对新型烟草制品征收消费税的合理性,介绍了美国和日本对电子烟和加热不燃烧烟草征收消费税的经验和政策效果。国际经验表明,对新型烟草制品征收消费税是大势所趋,我国应尽快对新型烟草制品征收消费税。

火针浅刺皮部治疗化疗性口腔溃疡

目的:观察火针浅刺皮部治疗化疗性口腔溃疡的临床疗效。方法:将符合纳入标准的60例化疗性口腔溃疡患者按随机数字表法分为观察组30例和对照组30例。观察组采用火针浅刺皮部,对照组采用康复新液,比较两组临床疗效、口腔溃疡愈合时间、止痛起效时间、止痛持续时间。结果:观察组临床有效率93.33%,显著优于对照组的86.67%。观察组治疗后口腔溃疡愈合时间为(3.30±1.61)d,显著优于对照组的(6.15±1.72)d(P<0.05)。观察组止痛起效时间为(1.52±0.24)min,显著优于对照组的(8.22±1.33)min(P<0.05)。观察组止痛持续时间为(23.08±2.41)h,显著优于对照组的(3.45±1.56) h(P<0.05)。结论:火针浅刺皮部治疗化疗性口腔溃疡的疗效和止痛效应均优于康复新液。

Hydraulic pressure inducing renal tubular epithelial-myofibroblast transdifferentiation in vitro

Objective： The effects of hydraulic pressure on renal tubular epithelial-myofibroblast transdifferentiation （TEMT） were investigated. Methods： We applied hydraulic pressure （50 cmH2O） to normal rat kidney tubular epithelial cells （NRK52E） for different durations. Furthermore, different pressure magnitudes were applied to cells. The morphology, cytoskeleton, and expression ofmyofibroblastic marker protein and transforming growth factor-β1 （TGF-β1） of NRK52E cells were examined. Results Disorganized actin filaments and formation of curling clusters in actin were seen in the cytoplasm of pressurized cells. We verified that de novo expression α-smooth muscle actin induced by pressure, which indicated TEMT, was dependent on both the magnitude and duration of pressure. TGF-β1 expression was significantly upregulated under certain conditions, which implies that the induction of TEMT by hydraulic pressure is related with TGF-β1. Conclusion： We illustrate for the first time that hydraulic pressure can induce TEMT in a pressure magnitude- and duration-dependent manner, and that this TEMT is accompanied by TGF-β1 secretion.

Price, Tax and Cigarette Smoking： Simulations of China＇s Tobacco Tax Policy

This paper explains the tobacco tax structure and cigarette pricing mechanism in China, develops a general analytical framework for analyzing the Chinese tobacco turnover tax system, and examines the effects of 2009 tobacco tax adjustment on cigarette prices and tax revenue. We find that although the tax is not the most important factor determining cigarette retail prices, the tobacco tax does significantly affect the tobacco industry＇s profits under the current tobacco monopoly system in China. Therefore, the adjustment of the tobacco excise tax in 2009 did not raise cigarette retail prices, instead government tax revenue increased. In other words, the net result of the tax adjustment was a transfer of the tobacco industry＇s profit to government tax revenues. Profit margins ultimately determine cigarette wholesale and retail prices. From the perspective of tobacco control, China needs to reform its tobacco tax system and collect taxes at the retail level to increase overall cigarette retail prices, as well as reduce the government＇s monopolization over cigarette productions and sales.

WiSeREmulator: An Emulation Framework for Wireless Structural Health Monitoring

Many competing approaches exist in evaluating sensor network solutions differing by levels of ease of use, cost, control, and realism. Existing work concentrates on simulating network protocols or emulating processing units at the machine cycle level. However, little has been done to emulate the sensors and the physical environments that they monitor. The main contribution of this work is the design of WiserEmulator, an emulation framework for structural health monitoring, which gracefully balances the trade-offs between realism, controllability, and cost. WiserEmulator consists of two main components -- a testbed of wireless sensor nodes and a software emulation environment. To emulate the excitation and response of piezo-electric transducers, as well as the wave propagation inside concrete structures, the COMSOL Multi-Physics software was utilized. Digitized sensing output from COMSOL was played back via a multi-channel Digital-to-Analog Converter （DAC） connected to the wireless sensor testbed. In addition to the emulation of concrete structures, WiSeREmulator also allows users to choose pre- stored data collected from field experiments and synthesized data. A user-friendly Graphical User Interface （GUI） was developed that facilitates intuitive configurations of experimental settings, control of the on-set and progression of the experiments, and real-time visualization of experimental results. We have implemented WiSeREmulator in MATLAB. This work advances the state of the art in providing low cost solutions to evaluating Cyber Physical Systems such as wireless structural health monitoring networks.

Potential of secondary aerosol formation from Chinese gasoline engine exhaust

Light-duty gasoline vehicles have drawn public attention in China due to their significant primary emissions of particulate matter and volatile organic compounds（VOCs）. However,little information on secondary aerosol formation from exhaust for Chinese vehicles and fuel conditions is available. In this study, chamber experiments were conducted to quantify the potential of secondary aerosol formation from the exhaust of a port fuel injection gasoline engine. The engine and fuel used are common in the Chinese market, and the fuel satisfies the China V gasoline fuel standard. Substantial secondary aerosol formation was observed during a 4–5 hr simulation, which was estimated to represent more than 10 days of equivalent atmospheric photo-oxidation in Beijing. As a consequence, the extreme case secondary organic aerosol（SOA） production was 426 ± 85 mg/kg-fuel, with high levels of precursors and OH exposure. The low hygroscopicity of the aerosols formed inside the chamber suggests that SOA was the dominant chemical composition. Fourteen percent of SOA measured in the chamber experiments could be explained through the oxidation of speciated single-ring aromatics. Unspeciated precursors, such as intermediate-volatility organic compounds and semi-volatile organic compounds, might be significant for SOA formation from gasoline VOCs. We concluded that reductions of emissions of aerosol precursor gases from vehicles are essential to mediate pollution in China.