Dear Editor,Wegener’s granulomatosis(WG)is a multisystem autoimmune disease characterized by granulomata of the respiratory tract and systemic necrotizing vasculitis(1)As the early clinical manifestations of WG are o...Dear Editor,Wegener’s granulomatosis(WG)is a multisystem autoimmune disease characterized by granulomata of the respiratory tract and systemic necrotizing vasculitis(1)As the early clinical manifestations of WG are often atypical,it is difficult to diagnosis,and treatment often be delayed,WG has been traditionally resulted in a multiple organ dysfunction or death[2].展开更多
Dear Editor,Diabetic macular edema(DME)is one of main sightthreatening conditions in patients with diabetic retinopathy(DR)[1].Anti-vascular endothelial growth factor(VEGF)therapy,glucocorticoid therapy,laser photocoa...Dear Editor,Diabetic macular edema(DME)is one of main sightthreatening conditions in patients with diabetic retinopathy(DR)[1].Anti-vascular endothelial growth factor(VEGF)therapy,glucocorticoid therapy,laser photocoagulation。展开更多
Dear Editor,Chorodial osteoma(CO) is a rare choroidal tumor characterized by the presence of mature bone tissue predominantly in the juxtapapillary or macularregion.CO mostly affects young healthy females in the secon...Dear Editor,Chorodial osteoma(CO) is a rare choroidal tumor characterized by the presence of mature bone tissue predominantly in the juxtapapillary or macularregion.CO mostly affects young healthy females in the second or third decades of life.It is unilateral in approximately 80%of cases[1],as patients have no obvious visual symptoms during the early stage of CO,and the growth of CO is slow.CO patients usually visit the eye clinic during the later stages of CO and have poor vision.Gradual decline in vision in CO patients is related to changes in retinal pigment epithelium(RPE)and photoreceptor atrophy.Choroidal neovascularization(CNV)and the resultant subretinal fluid and hemorrhage are the most frequent causes of sudden vision loss in CO[2].We report a rare case of bilateral CO with unilateral polypoidal choroidal vasculopathy(PCV)in a middle-aged male.展开更多
Dear Editor,We write to present a case of posterior scleritis associated with transient myopia,increased intraocular pressure and chorioretinal detachment.This study was performed in accordance with the Declaration of...Dear Editor,We write to present a case of posterior scleritis associated with transient myopia,increased intraocular pressure and chorioretinal detachment.This study was performed in accordance with the Declaration of Helsinki.展开更多
We present a case of circumscribed choroidal hemangioma (CCH) in Sturge-Weber syndrome in a 30-year-old woman with congenital port-wine stains on the left side of face involving the upper eyelid, cheek and the nose, a...We present a case of circumscribed choroidal hemangioma (CCH) in Sturge-Weber syndrome in a 30-year-old woman with congenital port-wine stains on the left side of face involving the upper eyelid, cheek and the nose, and she had undergone facial hemangioma surgery 3 years ago suggestive of Sturge-Weber syndrome. She presented with a 1-month history of rapidly decreased visual acuity (VA) to counting fingers in the left eye which had no prior history of visual problem. And there was no evidence of glaucoma. At 3 months after the treatment of the standard photodynannic therapy (PDT) the VA was 20/200. For some reasons, we have no idea about the changes of tumor thickness and subretinal fluid. We confirmed the curative effect of PDT treatment for CCH because of the significantly improved VA in the bad eye.展开更多
Dear Editor,Royal college of surgeons(RCS)rat is an inherited retinal degeneration rat caused by mutation of Mertk in the retinal pigment epithelial(RPE)cells^([1]).In this dystrophic rat,the dysfunction of RPEs leads...Dear Editor,Royal college of surgeons(RCS)rat is an inherited retinal degeneration rat caused by mutation of Mertk in the retinal pigment epithelial(RPE)cells^([1]).In this dystrophic rat,the dysfunction of RPEs leads to the progressive death of photoreceptors,with rods initially affected.Many studies have attempt to transplant various stem cells.展开更多
文摘Dear Editor,Wegener’s granulomatosis(WG)is a multisystem autoimmune disease characterized by granulomata of the respiratory tract and systemic necrotizing vasculitis(1)As the early clinical manifestations of WG are often atypical,it is difficult to diagnosis,and treatment often be delayed,WG has been traditionally resulted in a multiple organ dysfunction or death[2].
文摘Dear Editor,Diabetic macular edema(DME)is one of main sightthreatening conditions in patients with diabetic retinopathy(DR)[1].Anti-vascular endothelial growth factor(VEGF)therapy,glucocorticoid therapy,laser photocoagulation。
基金Supported by the National Basic Research of China(No.81600758)。
文摘Dear Editor,Chorodial osteoma(CO) is a rare choroidal tumor characterized by the presence of mature bone tissue predominantly in the juxtapapillary or macularregion.CO mostly affects young healthy females in the second or third decades of life.It is unilateral in approximately 80%of cases[1],as patients have no obvious visual symptoms during the early stage of CO,and the growth of CO is slow.CO patients usually visit the eye clinic during the later stages of CO and have poor vision.Gradual decline in vision in CO patients is related to changes in retinal pigment epithelium(RPE)and photoreceptor atrophy.Choroidal neovascularization(CNV)and the resultant subretinal fluid and hemorrhage are the most frequent causes of sudden vision loss in CO[2].We report a rare case of bilateral CO with unilateral polypoidal choroidal vasculopathy(PCV)in a middle-aged male.
文摘Dear Editor,We write to present a case of posterior scleritis associated with transient myopia,increased intraocular pressure and chorioretinal detachment.This study was performed in accordance with the Declaration of Helsinki.
文摘We present a case of circumscribed choroidal hemangioma (CCH) in Sturge-Weber syndrome in a 30-year-old woman with congenital port-wine stains on the left side of face involving the upper eyelid, cheek and the nose, and she had undergone facial hemangioma surgery 3 years ago suggestive of Sturge-Weber syndrome. She presented with a 1-month history of rapidly decreased visual acuity (VA) to counting fingers in the left eye which had no prior history of visual problem. And there was no evidence of glaucoma. At 3 months after the treatment of the standard photodynannic therapy (PDT) the VA was 20/200. For some reasons, we have no idea about the changes of tumor thickness and subretinal fluid. We confirmed the curative effect of PDT treatment for CCH because of the significantly improved VA in the bad eye.
基金Supported by the National Natural Science Foundation of China(No.81600758)。
文摘Dear Editor,Royal college of surgeons(RCS)rat is an inherited retinal degeneration rat caused by mutation of Mertk in the retinal pigment epithelial(RPE)cells^([1]).In this dystrophic rat,the dysfunction of RPEs leads to the progressive death of photoreceptors,with rods initially affected.Many studies have attempt to transplant various stem cells.
