Lomatogonium rotatum(L.rotatum)Fries ex Nym,a dry whole grass belonging to the family Gentianaceae,is widely used to treat liver diseases in Mongolian medicine.In Mongolian medicine,L.rotatum Fries ex Nym,also known a...Lomatogonium rotatum(L.rotatum)Fries ex Nym,a dry whole grass belonging to the family Gentianaceae,is widely used to treat liver diseases in Mongolian medicine.In Mongolian medicine,L.rotatum Fries ex Nym,also known as Digeda,is a rare medicinal herb with low yield and widespread clinical use.Currently,it is included in over 25 traditional Mongolian medicine prescriptions that help reduce heat,dispel xieri,enhance stomach function,and heal wounds.Recent studies have shown that L.rotatum Fries ex Nym contains a variety of metabolites,including flavonoids,xanthone compounds,terpenoids,organic acids,steroids,and alkaloids.In addition,its anti-hepatitis B,anti-inflammatory,anti-acute liver injury,and anti-obesity effects have been proven by pharmacological studies.In this review,we summarize the ecological resources,traditional pharmacodynamics,chemical constituents,and pharmacological actions of L.rotatum Fries ex Nym,with an aim to provide a theoretical basis for future applied research and new product development.展开更多
基金National Natural Science Foundation of China,No.81803845Natural Science Foundation of Inner Mongolia Autonomous Region,No.2018MS08040+1 种基金Construction Project of"Inner Mongolia Autonomous Region Mongolian Medicine and Food Source Protection and Utilization Innovation Team",No.190301Graduate Research Project of Inner Mongolia Minzu University,No.NMDBS1901.
文摘Lomatogonium rotatum(L.rotatum)Fries ex Nym,a dry whole grass belonging to the family Gentianaceae,is widely used to treat liver diseases in Mongolian medicine.In Mongolian medicine,L.rotatum Fries ex Nym,also known as Digeda,is a rare medicinal herb with low yield and widespread clinical use.Currently,it is included in over 25 traditional Mongolian medicine prescriptions that help reduce heat,dispel xieri,enhance stomach function,and heal wounds.Recent studies have shown that L.rotatum Fries ex Nym contains a variety of metabolites,including flavonoids,xanthone compounds,terpenoids,organic acids,steroids,and alkaloids.In addition,its anti-hepatitis B,anti-inflammatory,anti-acute liver injury,and anti-obesity effects have been proven by pharmacological studies.In this review,we summarize the ecological resources,traditional pharmacodynamics,chemical constituents,and pharmacological actions of L.rotatum Fries ex Nym,with an aim to provide a theoretical basis for future applied research and new product development.
