AIM： To determine the prevalence and characteristics of peripheral myopic retinopathy among a sample of Guangzhou office workers. METHODS： A cross-sectional study of Guangzhou Chinese office works in different depar...AIM： To determine the prevalence and characteristics of peripheral myopic retinopathy among a sample of Guangzhou office workers. METHODS： A cross-sectional study of Guangzhou Chinese office works in different departments and units of the Guangzhou Power Supply Bureau, China, in 2016. Myopic retinopathy was recorded and analyzed with a scanning laser ophthalmoscope and by slit-lamp microscopy combined with a three-mirror contact lens. RESULTS： In total, 1910 eyes of 955 subjects（508 females and 447 males） aged 21-59 y were included; 69.6% of these eyes were myopic. The myopia group had a younger age and worse uncorrected visual acuity（UCVA） and bestcorrected visual acuity（BCVA） when compared with hyperopia and emmetropia groups（P〈0.001）. The axial length（AL） was significantly longer, the spherical equivalent（SE） was more serious, and the optic nerve crescent was significantly larger in subjects with myopia than with hyperopia and emmetropia. Subjects with myopia, and especially high myopia, had the highest frequency of myopic retinal 18 changes（49.4%, P〈0.001） [white-without-pressure（43.8%, P〈0.001）, lattice degeneration（4.5%, P=0.044）] among the three groups. Logistic regression confirmed that any myopia（OR： 3.41, P〈0.001） [mild myopia（OR： 1.93, P=0.001）, moderate myopia（OR：3.64, P〈0.001）, and high myopia（OR：10.58, P〈0.001）], a greater AL（OR： 1.55, P〈0.001） and a much higher SE（OR： 0.77, P〈0.001） increased the risk for peripheral retinal changes.CONCLUSION： Myopia-related retinal changes are positively associated with greater AL, higher SE, and myopia.展开更多
基金Supported by the National Natural Science Foundation of China (No.81570865)the Guangdong Science and Technology Plan (No.2014A020212586)+1 种基金the Guangdong Natural Science Fund (No.2016A030310196 No.2017A030313543)
文摘AIM： To determine the prevalence and characteristics of peripheral myopic retinopathy among a sample of Guangzhou office workers. METHODS： A cross-sectional study of Guangzhou Chinese office works in different departments and units of the Guangzhou Power Supply Bureau, China, in 2016. Myopic retinopathy was recorded and analyzed with a scanning laser ophthalmoscope and by slit-lamp microscopy combined with a three-mirror contact lens. RESULTS： In total, 1910 eyes of 955 subjects（508 females and 447 males） aged 21-59 y were included; 69.6% of these eyes were myopic. The myopia group had a younger age and worse uncorrected visual acuity（UCVA） and bestcorrected visual acuity（BCVA） when compared with hyperopia and emmetropia groups（P〈0.001）. The axial length（AL） was significantly longer, the spherical equivalent（SE） was more serious, and the optic nerve crescent was significantly larger in subjects with myopia than with hyperopia and emmetropia. Subjects with myopia, and especially high myopia, had the highest frequency of myopic retinal 18 changes（49.4%, P〈0.001） [white-without-pressure（43.8%, P〈0.001）, lattice degeneration（4.5%, P=0.044）] among the three groups. Logistic regression confirmed that any myopia（OR： 3.41, P〈0.001） [mild myopia（OR： 1.93, P=0.001）, moderate myopia（OR：3.64, P〈0.001）, and high myopia（OR：10.58, P〈0.001）], a greater AL（OR： 1.55, P〈0.001） and a much higher SE（OR： 0.77, P〈0.001） increased the risk for peripheral retinal changes.CONCLUSION： Myopia-related retinal changes are positively associated with greater AL, higher SE, and myopia.
