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乳腺癌的分子核医学研究进展 被引量:3
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作者 李翠翠 杨琦 +1 位作者 王荣福 康磊 《中国肿瘤临床》 CAS CSCD 北大核心 2022年第4期193-196,共4页
乳腺癌是一种具有高度异质性、高发病率、高死亡率的癌症。个体化的早期准确诊断和治疗是提高患者生存率的有效手段。分子核医学将分子生物学技术与核医学相结合,在分子、细胞、活体水平对机体生物学行为进行定性和定量研究,是一种高度... 乳腺癌是一种具有高度异质性、高发病率、高死亡率的癌症。个体化的早期准确诊断和治疗是提高患者生存率的有效手段。分子核医学将分子生物学技术与核医学相结合,在分子、细胞、活体水平对机体生物学行为进行定性和定量研究,是一种高度可重复、安全且无创的影像技术,广泛应用于各种恶性肿瘤的诊断、分期、预后预测和疗效评估。本文主要对分子核医学代谢显像、受体显像、基因显像和免疫PET显像在乳腺癌中的应用进行综述。 展开更多
关键词 乳腺癌 分子核医学 代谢显像 受体显像 免疫PET显像
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Research Progress of miRNAs in Rice(Oryza sativa L.)under Biotic and Abiotic Stresses 被引量:1
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作者 Yu LI Liquan WU +1 位作者 rongfu wang Juan LI 《Agricultural Biotechnology》 CAS 2016年第4期46-50,共5页
Stresses are defined as a variety of environmental factors that pose adverse impacts on plant growth and survival. Rice is an important food crop, whose quality and yield may be affected by environmental stresses. Mic... Stresses are defined as a variety of environmental factors that pose adverse impacts on plant growth and survival. Rice is an important food crop, whose quality and yield may be affected by environmental stresses. MicroRNAs play an important role in response to stresses, which regulate gene expression at the post-transcription level by cleaving target mRNAs and inhibiting mRNA translation. This paper summarized the mechanism of action of miRNAs and introduced research progress of miRNAs in rice under biotic and abiotic stresses, which provided reference for revealing the functional role of rice miRNAs in stress resistance. 展开更多
关键词 RICE MIRNA Biotic/abiotic stresses
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Role of F-18 FDG PET/CT imaging in the diagnosis of paraneoplastic neurological syndromes
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作者 Lei Kang Xiaojie Xu +1 位作者 Hongwei Sun rongfu wang 《The Chinese-German Journal of Clinical Oncology》 CAS 2014年第10期494-498,共5页
Paraneoplastic neurological syndromes(PNS) is a series of rare neurologic disorders which happen with an underlying malignancy. It has various clinical symptoms proceding to the diagnosis of tumors. Although the abnor... Paraneoplastic neurological syndromes(PNS) is a series of rare neurologic disorders which happen with an underlying malignancy. It has various clinical symptoms proceding to the diagnosis of tumors. Although the abnormality of anti-neuronal antibodies is suggestive of PNS and tumors, there exist many false positive and false negative cases. The diagnosis of PNS is usually a challenge in clinic. Positron emission tomography/computed tomography(PET/CT) imaging is an anatomical and functional fusion imaging method, which provides the whole-body information by single scan. Fluorodeoxyglucose(FDG) PET/CT imaging can not only detect potential malignant lesions in the whole body, but also assess functional abnormality in the brain. In this review, the mechanism, clinical manifestation, diagnostic procedure and the recent progress of the utility of FDG PET/CT in PNS are introduced respectively. 展开更多
关键词 paraneoplastic neurological syndrome (PNS) fluorodeoxyglucose (FDG) positron emission tomography/com-puted tomography (PET/CT) anti-neuronal antibody
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