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Unilateral mimicking bilateral BPPV- a forgotten entity? Characteristics of a largecohort of patients, comparison with posterior canal BPPV and clinical implications 被引量:2
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作者 Lea Pollak ronit gilad Tal Michael 《Journal of Otology》 CSCD 2021年第4期252-257,共6页
Objective: Unilateral mimicking bilateral benign paroxysmal positional vertigo (umb-BPPV) was attributed to inappropriate head positioning during testing of the posterior canal. Despite its inclusion in theDiagnostic ... Objective: Unilateral mimicking bilateral benign paroxysmal positional vertigo (umb-BPPV) was attributed to inappropriate head positioning during testing of the posterior canal. Despite its inclusion in theDiagnostic criteria for the classification of vestibular disorders of the Barany Society, the clinical characteristics and treatment responsiveness of this BPPV subtype have not been intensively studied.Methods: Records of patients with BPPV seen at a single outpatient dizziness clinic during the years 2000e2020 were reviewed. Eighty seven patients with umb-BPPV and 86 random patients with posteriorcanal BPPV (p-BPPV) were retrieved. Their demographics and BPPV characteristics were analyzed.Results: Patients' and BPPV characteristics were similar in umb- and p-BPPV except for the prevalence ofmales in the umb-BPPV group. No differences were found between treatment responsiveness and recurrences in both groups. The recurrence rate of umb-BPPV was not influenced by age, gender, BPPV side,duration of symptoms or treatment responsiveness during the first attack.Conclusions: In accordance with our hypothesis about mixed canalo- and cupulolithiasis as the underlying mechanism of umb-BPPV, patients did not differ in characteristics and treatment responsivenessfrom p-BPPV patients. Recognition of umb-BPPV is important since inappropriate treatment can cause anunnecessary delay in therapy success. 展开更多
关键词 Benign paroxysmal positional vertigo Canalo-and cupulolithiasis
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用药点滴:服用西地那非发生强直阵挛性癫痫发作2例报道
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作者 ronit gilad Yair Lampl +2 位作者 Yehiel Eshel Menachem Sadeh 薛兆英 《英国医学杂志中文版》 2003年第2期89-90,共2页
西地那非(Sidenafil,万艾可,俗称伟哥)是一种非特异性5型磷酸二酯酶抑制剂,对环鸟苷单磷酸酯合成酶(cGMP)具有抑制作用。一氧化氮释放增多可导致cGMP水平提高。其主要临床效应是促进海绵体平滑肌松弛,进入阴茎血流量增加,有助于勃起功... 西地那非(Sidenafil,万艾可,俗称伟哥)是一种非特异性5型磷酸二酯酶抑制剂,对环鸟苷单磷酸酯合成酶(cGMP)具有抑制作用。一氧化氮释放增多可导致cGMP水平提高。其主要临床效应是促进海绵体平滑肌松弛,进入阴茎血流量增加,有助于勃起功能障碍的缓解。 较轻的副作用为头痛、潮红、鼻塞、色彩视觉缺陷和严重的心血管、脑血管副作用,均有报道,到目前为止尚未报道属于神经系统副作用的惊厥性癫痫发作。本文作者报告2例病人在服用西地那非不久,首次发生癫痫发作。 展开更多
关键词 西地那非 强直阵挛性癫痫发作 非特异性5型磷酸二醋酶抑制剂 副作用 性功能障碍
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