期刊文献+
共找到1篇文章
< 1 >
每页显示 20 50 100
Feasibility of iFISH patterns in hematologic malignancies among Congolese patients at Kinshasa University clinics
1
作者 Mireille Solange Nganga Nkanga Benjamin Longo-Mbenza +10 位作者 Peter Vandenberghe Fons Verdonck Venant Tchokonte-Nana Nkama Claude Nlandu roth laure mapapa miakassissa Paul Roger Beia Kazadi Antoine Lufimbo Katawandja Jacques Bikaula Ngwidiwo Ntolo Jean-Pierre Mufuta Kuanda Thomas Solo Mbombo Aurore Cecilia Orphée Beia 《Asian Pacific Journal of Tropical Biomedicine》 SCIE CAS 2017年第12期1116-1119,共4页
Objective: To analyze the feasibility of detecting Ph1 in leukemia patients in the Kinshasa University Clinics in the Democratic Republic of Congo, at KU Leuven, Belgium.Methods: Bone marrow and peripheral blood sampl... Objective: To analyze the feasibility of detecting Ph1 in leukemia patients in the Kinshasa University Clinics in the Democratic Republic of Congo, at KU Leuven, Belgium.Methods: Bone marrow and peripheral blood samples with chronic myeloid leukemia,acute myeloid leukemia or acute leukocytes leukemia were obtained from 32 patients in Kinshasa University clinics in the Democratic Republic of Congo and transferred to KU Leuven in Belgium for i FISH feasibility. Ph^1 was detected by using a remote analysis of interphase fluorescence in situ hybridization(i FISH).Results: Out of the 32 patients involved in this study, 65.6%(n = 21) of the cases were successfully tested, of which 52.4%(n = 11) were i FISH positives for the variant t(9;22)(presence of Ph^1) in chronic myeloid leukemia samples and 47.6%(n = 10) negatives in all subtypes of hematological malignancies. However, there was a female predominance in chronic myeloid leukemia samples Ph^1-positives by i FISH, whereas no sexual influence was observed on acute subtypes of leukemia.Conclusions: i FISH analysis is feasible on samples obtained from remote sites in the Democratic Republic of Congo. However, the optimization of the sample storage is necessary to further improve i FISH's performance. 展开更多
关键词 iFISH Ph^1 Democratic Republic of Congo LEUKEMIA Bone marrow BLOOD
下载PDF
上一页 1 下一页 到第
使用帮助 返回顶部