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STUDIES ON DOPAMINE RECEPTORS AND TETRAHYDROPROTOBERBERINES.Ⅲ.3D-QSAR STUDY ON TETRAHYDROPROTOBERBERINES USING COMFA APPROACH
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作者 yun TANG Kai Xian CHEN +2 位作者 Hua Liang jiANG Guo Zhang jiN ru yun ji(shanghai institute of materia medica. chinese academy of sciences,294 taiyuan road, shanghai 200031) 《Chinese Chemical Letters》 SCIE CAS CSCD 1996年第3期249-252,共4页
Using comparative molecular field analysis approach, the interaction of 17 tetrahydroprotdederines to D1 reccptor and15 ones to D2 reccptor have ben studied by 3D-QsAR. respectively. The results indicated that the int... Using comparative molecular field analysis approach, the interaction of 17 tetrahydroprotdederines to D1 reccptor and15 ones to D2 reccptor have ben studied by 3D-QsAR. respectively. The results indicated that the interactions of THPBs withdopamine receplors were primarily clectrostatic interactions. with more positive charge in lignnd and more negative in receptor. 展开更多
关键词 QSAR STUDY APPROACH AND
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