The pollution characteristics of ambient fine particulate matter（PM2.5） containing polycyclic aromatic hydrocarbons（PAHs） and nitrated PAHs（NPAHs） in samples collected during a typical winter time period in Taiy...The pollution characteristics of ambient fine particulate matter（PM2.5） containing polycyclic aromatic hydrocarbons（PAHs） and nitrated PAHs（NPAHs） in samples collected during a typical winter time period in Taiyuan of China were investigated.The obtained results revealed that the mean mass concentrations of PM2.5,SPAHs（sum of 16 PAHs） and SNPAHs（sum of 3 NPAHs） on PM2.5were161.4 mg/m3,119.8 ng/m3and 0.446 ng/m3,respectively.Diagnostic ratios of PAHs and NPAHs implied that coal consumption might be the main source of the PM2.5pollution.The measured PM2.5mass concentrations,BaP equivalent toxicity（28.632 ng/m3） and individual carcinogenicity index（3.14 10 5） were much higher than those of the recommended safety standards.展开更多
The aim of this study was to investigate the chemical compositions of chalk dust and examine the adverse effects of fine chalk particle matters（PM（2.5）） on rat alveolar macrophages（AMs） in vitro.Morphologies and...The aim of this study was to investigate the chemical compositions of chalk dust and examine the adverse effects of fine chalk particle matters（PM（2.5）） on rat alveolar macrophages（AMs） in vitro.Morphologies and element concentrations of chalk particles were analyzed using quantitative energydispersive electron probe X-ray microanalysis（ED-EPMA）.The oxidative response of AMs exposed to chalk PM（2.5） was measured by luminol-dependent chemiluminescence（CL）.The results showed that（1）Chalk dust was mainly composed of gypsum（CaSO4）,calcite（CaCO3）/dolomite（CaMg（CO3）2）,and organic adhesives;（2） Fine chalk particles induced the AM production of CL,which was inhibited by about 90%by diphenyleneiodonium chloride（DPI）.Based on these results,we showed that cytotoxicity of chalk PM（2.5） may be related to the reactive oxygen species（ROS） generation.展开更多
基金supported by the National Natural Science Foundation of China (Nos. 21177078, 21175086, 21175025 and 41271531)Supported by Shanxi Scholarship Council of China (No. 2013-16)100 talents program of Shanxi Province
文摘The pollution characteristics of ambient fine particulate matter（PM2.5） containing polycyclic aromatic hydrocarbons（PAHs） and nitrated PAHs（NPAHs） in samples collected during a typical winter time period in Taiyuan of China were investigated.The obtained results revealed that the mean mass concentrations of PM2.5,SPAHs（sum of 16 PAHs） and SNPAHs（sum of 3 NPAHs） on PM2.5were161.4 mg/m3,119.8 ng/m3and 0.446 ng/m3,respectively.Diagnostic ratios of PAHs and NPAHs implied that coal consumption might be the main source of the PM2.5pollution.The measured PM2.5mass concentrations,BaP equivalent toxicity（28.632 ng/m3） and individual carcinogenicity index（3.14 10 5） were much higher than those of the recommended safety standards.
基金supported by grants from the National Natural Science Foundation of China(Nos.21107064,2140509,21175086 and 21177078)by grant from Shanxi Scholarship Council of China(Nos.2013-012 and 2013-016)
文摘The aim of this study was to investigate the chemical compositions of chalk dust and examine the adverse effects of fine chalk particle matters（PM（2.5）） on rat alveolar macrophages（AMs） in vitro.Morphologies and element concentrations of chalk particles were analyzed using quantitative energydispersive electron probe X-ray microanalysis（ED-EPMA）.The oxidative response of AMs exposed to chalk PM（2.5） was measured by luminol-dependent chemiluminescence（CL）.The results showed that（1）Chalk dust was mainly composed of gypsum（CaSO4）,calcite（CaCO3）/dolomite（CaMg（CO3）2）,and organic adhesives;（2） Fine chalk particles induced the AM production of CL,which was inhibited by about 90%by diphenyleneiodonium chloride（DPI）.Based on these results,we showed that cytotoxicity of chalk PM（2.5） may be related to the reactive oxygen species（ROS） generation.
