TCP-LTE/5G Cross-layer performance analysis tool for high mobility data networking and a case study on high-speed railway

Nowadays,high mobility scenarios have become increasingly common.The widespread adoption of High-speed Rail(HSR)in China exemplifies this trend,while more promising use cases,such as vehicle-to-everything,continue to emerge.However,the Internet access provided in high mobility environments stllstruggles to achieve seamless connectivity.The next generation of wireless cellular technology 5 G further poses more requirements on the endto-end evolution to fully utilize its ultra-high band-width,while existing network diagnostic tools focus on above-IP layers or below-IP layers only.We then propose HiMoDiag,which enables flexible online analysis of the network performance in a cross-layer manner,i.e.,from the top(application layer)to the bottom(physical layer).We believe HiMoDiag could greatly simplify the process of pinpointing the deficiencies of the Internet access delivery on HSR,lead to more timely optimization and ultimately help to improve the network performance.

Impact of Sharp Fluctuations of Live Pig Prices on Financial Capacity of Pig Breeding Enterprises : An Analysis Based on the Data of Listed Enterprises from 2018 to 2021

Based on the general equilibrium theory of microeconomics,this study first analyzed the causes of sharp fluctuations in live pig prices,and then explored the financial capabilities of enterprises during the sharp fluctuations of live pig prices by using the financial data of 4 typical top listed enterprises from 2018 to 2021.By comparing the changes in the capabilities of enterprises,the impact of price on the financial capability of enterprises and differences were identified.The research results showed that the price of live pigs played a decisive role in enterprise profits,and there were huge differences in the fluctuation period.In the sharp increase period of price,price temptation is easy to cause enterprises to over-invest,resulting in excessive growth of enterprise assets,and increasing the business risk of enterprises.Based on the above conclusions,some policy suggestions were put forward to promote the stable development of industry from the three levels of enterprises,industries and government departments.

CA IX-targeted Ag_(2)S quantum dots bioprobe for NIR-II imaging-guided hypoxia tumor chemo-photothermal therapy

Hypoxia is the common characteristic of almost all solid tumors,which prevents therapeutic drugs from reaching the tumors.Therefore,the development of new targeted agents for the accurate diagnosis of hypoxia tumors is widely concerned.As carbonic anhydrase IX(CA IX)is abundantly distributed on the hypoxia tumor cells,it is considered as a potential tumor biomarker.4-(2-Aminoethyl)benzenesulfonamide(ABS)as a CA IX inhibitor has inherent inhibitory activity and good targeting effect.In this study,Ag_(2)S quantum dots(QDs)were used as the carrier to prepare a novel diagnostic and therapeutic bioprobe(Ag_(2)S@polyethylene glycol(PEG)-ABS)through ligand exchange and amide condensation reaction.Ag_(2)S@PEG-ABS can selectively target tumors by surface-modified ABS and achieve accurate tumor imaging by the near infrared-II(NIR-II)fluorescence characteristics of Ag_(2)S QDs.PEG modification of Ag_(2)S QDs greatly improves its water solubility and stability,and therefore achieves high photothermal stability and high photothermal conversion efficiency(PCE)of 45.17%.Under laser irradiation,Ag_(2)S@PEG-ABS has powerful photothermal and inherent antitumor combinations on colon cancer cells(CT-26)in vitro.It also has been proved that Ag_(2)S@PEG-ABS can realize the effective treatment of hypoxia tumors in vivo and show good biocompatibility.Therefore,it is a new efficient integrated platform for the diagnosis and treatment of hypoxia tumors.