In the past decades,advances in high-throughput technologies have led to the generation of huge amounts of biological data that require analysis and interpretation.Recently,nonnegative matrix factorization （NMF） has...In the past decades,advances in high-throughput technologies have led to the generation of huge amounts of biological data that require analysis and interpretation.Recently,nonnegative matrix factorization （NMF） has been introduced as an efficient way to reduce the complexity of data as well as to interpret them,and has been applied to various fields of biological research.In this paper,we present CloudNMF,a distributed open-source implementation of NMF on a MapReduce framework.Experimental evaluation demonstrated that CloudNMF is scalable and can be used to deal with huge amounts of data,which may enable various kinds of a high-throughput biological data analysis in the cloud.CloudNMF is freely accessible at http：//admis.fudan.edu.cn/projects/CloudNMF.html.展开更多
基金financially supported by National High Technology Research and Development Program of China(863 Program Grant No.2012AA020403)National Natural Science Foundation of China(Grant Nos.61173118 and 61272380)
文摘In the past decades,advances in high-throughput technologies have led to the generation of huge amounts of biological data that require analysis and interpretation.Recently,nonnegative matrix factorization （NMF） has been introduced as an efficient way to reduce the complexity of data as well as to interpret them,and has been applied to various fields of biological research.In this paper,we present CloudNMF,a distributed open-source implementation of NMF on a MapReduce framework.Experimental evaluation demonstrated that CloudNMF is scalable and can be used to deal with huge amounts of data,which may enable various kinds of a high-throughput biological data analysis in the cloud.CloudNMF is freely accessible at http：//admis.fudan.edu.cn/projects/CloudNMF.html.
