A new isoprenylated flavonol, named broussonol A (1) was isolated from the leaves of Broussonetia kazinoki Sieb. The structure of broussonol A was characterized by chemical and spectral methods.
A new alkaloid, named prolifine (1), was isolated along with four known alkaloids, liriodenine (2), 6-hydroxyonychine (3), isooncodine (4) and discretamine (5) from the roots of Saccopetalum prolificum. The structure ...A new alkaloid, named prolifine (1), was isolated along with four known alkaloids, liriodenine (2), 6-hydroxyonychine (3), isooncodine (4) and discretamine (5) from the roots of Saccopetalum prolificum. The structure of I was elucidated on the basis of spectroscopic and chemical methods.展开更多
Calamistrin E, the first Annonaceous acetogenin with C=C bond in the aliphatic chain from the genus Uvaria was isolated from U. calamistrata. Its structure including relative and absolute configurations was determined...Calamistrin E, the first Annonaceous acetogenin with C=C bond in the aliphatic chain from the genus Uvaria was isolated from U. calamistrata. Its structure including relative and absolute configurations was determined by chemical derivation and spectral analysis.展开更多
A new dihydroflavone (1), named macrophyllol A, was isolated from the roots of Uvaria macrophylla. Its structure was elucidated on the basis of spectroscopic evidence.
A new sesquiterpenoid compound named ligustilone was isolated from the roots of Ligusticum sinense Oliv. Based on the chemical and spectral studies especially 2DNMR including H-1, H-1 COSY, H-1, C-13 COSY and COLOC te...A new sesquiterpenoid compound named ligustilone was isolated from the roots of Ligusticum sinense Oliv. Based on the chemical and spectral studies especially 2DNMR including H-1, H-1 COSY, H-1, C-13 COSY and COLOC techniques, its structure has been established as a bisabolane derivative and showed as 1. The absolute configuration was determined by CD data.展开更多
Ligustiphenol (1), a new sesquiterpenoid with bisabolane skeleton, has beenisolated from the alcohol extract of roots of Ligusticum silence Oliv, and its strcutureincluding absolute configuration established on the ba...Ligustiphenol (1), a new sesquiterpenoid with bisabolane skeleton, has beenisolated from the alcohol extract of roots of Ligusticum silence Oliv, and its strcutureincluding absolute configuration established on the basis of spectral and chemicalevidences.展开更多
Two mild-cytotoxic bistetrahydrofuran (THF) ring annonaceous acetogenins named calamistrins F(1) and G(2) were isolated from the ethanolic extract of the roots of U. calamistrata Hance. Their structures including the ...Two mild-cytotoxic bistetrahydrofuran (THF) ring annonaceous acetogenins named calamistrins F(1) and G(2) were isolated from the ethanolic extract of the roots of U. calamistrata Hance. Their structures including the relative and absolute configurations were determined by chemical derivation and spectral analysis. Calamistrins F and G were a pair of epimers at C-26 which both had THF ring from C-18 to C-25 and three OH groups at C-5, C-17 and C-26.展开更多
By means of variable temperature NMR spectra, conformation of 8-C-glucosyl prunetin, isolated from the leaves of Dalbergia hainanensis (Leguminosae), was studied. The restricted rotation around the C (sp3)-C (sp2) bo...By means of variable temperature NMR spectra, conformation of 8-C-glucosyl prunetin, isolated from the leaves of Dalbergia hainanensis (Leguminosae), was studied. The restricted rotation around the C (sp3)-C (sp2) bond in the C-glucosides isoflavonoid results in two main conformers (syn and anti). With the help of MM calculation, the preferred conformation A has H-1 gauche to the 7-OCH3. The barrier to rotation was 18.1 kcal/mol. This result agrees with the calculated value 16.2 kcal/mol of free energy of activation for the interconversion between the conformers.展开更多
Two new compounds, gonioquinone (1) and goniofufurone acetonide (2), have been isolated from the roots of Goniothalamus cheliensis Hu. Their structures were determined on the basis of spectral and chemical evidence.
A New flavone named Macrophyllol was isolated from the roots of Uvaria macrophylla. The structure of 1 was elucidated on the basis of spectroscopic evidence.
A new bislabdane-type diterpenoid lanceolactin (I), was isolated from the roots of Cunninghamia lanceolata. Its structure was elucidated on the basis of spectroscopic methods, especially 2D-NMR techniques.
Two new styryllactones, iso-goniopypyrone and 8-acetyl-9-deoxygoniopypyrone, were isolated from the roots of Goniothalamus cheliensis. Their structure were elucidated on the basis of spectroscopic and chemical eviden...Two new styryllactones, iso-goniopypyrone and 8-acetyl-9-deoxygoniopypyrone, were isolated from the roots of Goniothalamus cheliensis. Their structure were elucidated on the basis of spectroscopic and chemical evidences.展开更多
A new flavanone named macrouroine C (1) was isolated from the bark of Morus macroura Miq.. The structure of 1 was elucidated mainly on the basis of spectroscopic evidence.
Coniselin, a new natural compound, was isolated from the roots of Coniselium Vaginatum Thell.Its structure was elucidated by means of spectroscopic analysis (UV, IR, MS, NMR, DEPT) and confirmed by total synthesis.
Two new polyoxygenated cyclohexenes, named uvacalolA (1),and B (2) were isolated from the rhizomes of Uvaria calamistrata. On the basis of spectral analysis and chemical derivatization, including preparation of Mosher...Two new polyoxygenated cyclohexenes, named uvacalolA (1),and B (2) were isolated from the rhizomes of Uvaria calamistrata. On the basis of spectral analysis and chemical derivatization, including preparation of Mosher esters, the structure of 1 to 2 were established.展开更多
文摘A new isoprenylated flavonol, named broussonol A (1) was isolated from the leaves of Broussonetia kazinoki Sieb. The structure of broussonol A was characterized by chemical and spectral methods.
文摘A new alkaloid, named prolifine (1), was isolated along with four known alkaloids, liriodenine (2), 6-hydroxyonychine (3), isooncodine (4) and discretamine (5) from the roots of Saccopetalum prolificum. The structure of I was elucidated on the basis of spectroscopic and chemical methods.
文摘Calamistrin E, the first Annonaceous acetogenin with C=C bond in the aliphatic chain from the genus Uvaria was isolated from U. calamistrata. Its structure including relative and absolute configurations was determined by chemical derivation and spectral analysis.
文摘A new dihydroflavone (1), named macrophyllol A, was isolated from the roots of Uvaria macrophylla. Its structure was elucidated on the basis of spectroscopic evidence.
文摘A new sesquiterpenoid compound named ligustilone was isolated from the roots of Ligusticum sinense Oliv. Based on the chemical and spectral studies especially 2DNMR including H-1, H-1 COSY, H-1, C-13 COSY and COLOC techniques, its structure has been established as a bisabolane derivative and showed as 1. The absolute configuration was determined by CD data.
文摘Ligustiphenol (1), a new sesquiterpenoid with bisabolane skeleton, has beenisolated from the alcohol extract of roots of Ligusticum silence Oliv, and its strcutureincluding absolute configuration established on the basis of spectral and chemicalevidences.
文摘Two mild-cytotoxic bistetrahydrofuran (THF) ring annonaceous acetogenins named calamistrins F(1) and G(2) were isolated from the ethanolic extract of the roots of U. calamistrata Hance. Their structures including the relative and absolute configurations were determined by chemical derivation and spectral analysis. Calamistrins F and G were a pair of epimers at C-26 which both had THF ring from C-18 to C-25 and three OH groups at C-5, C-17 and C-26.
文摘By means of variable temperature NMR spectra, conformation of 8-C-glucosyl prunetin, isolated from the leaves of Dalbergia hainanensis (Leguminosae), was studied. The restricted rotation around the C (sp3)-C (sp2) bond in the C-glucosides isoflavonoid results in two main conformers (syn and anti). With the help of MM calculation, the preferred conformation A has H-1 gauche to the 7-OCH3. The barrier to rotation was 18.1 kcal/mol. This result agrees with the calculated value 16.2 kcal/mol of free energy of activation for the interconversion between the conformers.
基金This research was supported by National 973 Project(G1998051120).
文摘Two new compounds, gonioquinone (1) and goniofufurone acetonide (2), have been isolated from the roots of Goniothalamus cheliensis Hu. Their structures were determined on the basis of spectral and chemical evidence.
基金This project is supported by the National Natural Science Foundation of Beijing
文摘A New flavone named Macrophyllol was isolated from the roots of Uvaria macrophylla. The structure of 1 was elucidated on the basis of spectroscopic evidence.
文摘A new bislabdane-type diterpenoid lanceolactin (I), was isolated from the roots of Cunninghamia lanceolata. Its structure was elucidated on the basis of spectroscopic methods, especially 2D-NMR techniques.
文摘Two new styryllactones, iso-goniopypyrone and 8-acetyl-9-deoxygoniopypyrone, were isolated from the roots of Goniothalamus cheliensis. Their structure were elucidated on the basis of spectroscopic and chemical evidences.
文摘A new flavanone named macrouroine C (1) was isolated from the bark of Morus macroura Miq.. The structure of 1 was elucidated mainly on the basis of spectroscopic evidence.
文摘Coniselin, a new natural compound, was isolated from the roots of Coniselium Vaginatum Thell.Its structure was elucidated by means of spectroscopic analysis (UV, IR, MS, NMR, DEPT) and confirmed by total synthesis.
文摘Two new polyoxygenated cyclohexenes, named uvacalolA (1),and B (2) were isolated from the rhizomes of Uvaria calamistrata. On the basis of spectral analysis and chemical derivatization, including preparation of Mosher esters, the structure of 1 to 2 were established.