In this paper,we review the results of previous studies and summarize the effects of various factors on the regulation of bone metabolism in traumatic bone infections.Infection-related bone destruction incorporates pa...In this paper,we review the results of previous studies and summarize the effects of various factors on the regulation of bone metabolism in traumatic bone infections.Infection-related bone destruction incorporates pathogens and iatrogenic factors in the process of bone resorption dominated by the skeletal and immune systems.The development of bone immunology has established a bridge of communication between the skeletal system and the immune system.Exploring the effects of pathogens,skeletal systems,immune systems,and antibacterials on bone repair in infectious conditions can help improve the treatment of these diseases.展开更多
基金The study was supported by Medical Research Funding of PLA of China(grant number:AWS14C003)Special Funds for Social Undertaking and Livelihood Security Projects of Chongqing(grant number:CSTC2016SHMSZX130068)+1 种基金Youth Development Program of Medical Technology of PLA(grant number:16QNP103)and Scientific and Medical Research Project of Chongqing(grant number:2018ZDXM030).
文摘In this paper,we review the results of previous studies and summarize the effects of various factors on the regulation of bone metabolism in traumatic bone infections.Infection-related bone destruction incorporates pathogens and iatrogenic factors in the process of bone resorption dominated by the skeletal and immune systems.The development of bone immunology has established a bridge of communication between the skeletal system and the immune system.Exploring the effects of pathogens,skeletal systems,immune systems,and antibacterials on bone repair in infectious conditions can help improve the treatment of these diseases.