This study reports the investigations for repair of thermoplastic based automotive bumpers and bars with modified friction stir welding(MFSW)process.For MFSW,consumable tool of polyamide6(PA6)composite has been used f...This study reports the investigations for repair of thermoplastic based automotive bumpers and bars with modified friction stir welding(MFSW)process.For MFSW,consumable tool of polyamide6(PA6)composite has been used for joining of acrylonitrile butadiene styrene(ABS)composites.The dissimilar thermoplastics were processed for maintaining a useful range of melt flow properties followed by preparation of feed stock filament for fused deposition modeling(FDM)process through screw extrusion.Finally,3D printed PA6 based consumable rapid tool(RT)was prepared for MFSW.The joints prepared were subjected to flexural,hardness,morphological and thermal testing.The study has suggested the that maximum mechanical strength was obtained for sample welded at 1400 r/min,50 mm/min transverse speed and 3 mm plunge depth,whereas the minimum mechanical strength was obtained for sample welded at 1000 r/min,30 mm/min transverse speed and 2 mm plunge depth.The results are also supported with thermal analysis and photomicrographs.展开更多
Fused deposition modeling(FDM) is one of the latest rapid prototyping techniques in which parts can be manufactured at a fast pace and are manufactured with a high accuracy. This research work is carried out to study ...Fused deposition modeling(FDM) is one of the latest rapid prototyping techniques in which parts can be manufactured at a fast pace and are manufactured with a high accuracy. This research work is carried out to study the friction and wear behavior of parts made of newly developed Nylon6-Fe composite material by FDM. This work also involves the comparison of the friction and wear characteristics of the Nylon6-Fe composite with the existing acrylonitrile butadiene styrene(ABS) filament of the FDM machine. This Is carried out on the pin on disk setup by varying the load(5, 10, 15 and 20 N) and speed(200 and 300 r/min). It is concluded that the newly developed composite is highly wear resistant and can be used in industrial applications where wear resistance is of paramount importance. Morphology of the surface in contact with the Nylon6-Fe composite and ABS is also carried out.展开更多
The present study reports investigations on rheological,mechanical,thermal,tribological and morphological properties of feedstock filaments prepared with polylactic acid-polyether ketone ketone-hydroxyapatite-chitosan...The present study reports investigations on rheological,mechanical,thermal,tribological and morphological properties of feedstock filaments prepared with polylactic acid-polyether ketone ketone-hydroxyapatite-chitosan(PLA-PEKK-HAp-CS)composite for 3D printing of functional prototypes.The study consists of a series of melt processing operations on melt flow index(MFI)setup as per ASTM D-1238 for melt flow certainty followed by fixation of reinforcement composition/proportion as 94%PEKK-4%HAp-2%CS(B)by mass in PLA matrix(A).The blending of reinforcement and preparation of feedstock filament for fused deposition modeling(FDM)set up has been performed on commercial twin screw extruder(TSE).The results of study suggest that feedstock filaments prepared with blend of 95%A-5%B(by mass)at 200℃processing temperature and 100 r/min rotational speed on TSE resulted into better tensile properties(35.9 MPa peak strength and 32.3 MPa break strength)with 6.24%surface porosity,42.67 nm surface roughness(R_(a))and acceptable heat capacity(2.14 J/g).However as regards to tribological behavior,the minimum wear of 316μm was observed for sample with poor tensile properties.As regards to crash application for scaffolds the maximum toughness of 1.16 MPa was observed for 85%A-15%B(by mass)at 200℃processing temperature and 150 r/min rotational speed on TSE.展开更多
Infections by mosquito-borne diseases represent one of the leading causes of death in third world countries.The rapid progression of resistance to conventional insecticide causes a significant threat to the highly eff...Infections by mosquito-borne diseases represent one of the leading causes of death in third world countries.The rapid progression of resistance to conventional insecticide causes a significant threat to the highly efficient preventive methods currently in place.Insect neuropeptidergic system offers potential targets to control the insect vectors.The essential roles of the neuropeptide ecdysis triggering hormone(ETH)in insect development and reproduction led us to attempt understanding of the fundamentals of the biochemical interaction between ETH and its receptor in the African malaria mosquito Anopheles gambiae.One of two ETH peptides of the African malaria mosquito(AgETH1),a small peptide hormone with 17 amino acid residues(SESPGFFIKLSKSVPRI-NH2),was studied to elucidate its molecular structure.N-termini deletions and mutations of conserved amino acids in the ligand revealed the critical residues for the receptor activation.The solution structure of AgETH1 using 2D 1H-1H nuclear magnetic resonance(NMR)spectroscopy and nuclear overhauser effect(NOE)derived constraints revealed a short alpha helix between residues 3S and 11S.The NMR solution structure of AgETH1 will be of significant assistance for designing a new class of insecticidal compounds that acts on the AgETH receptor aiming for in silico docking studies.展开更多
文摘This study reports the investigations for repair of thermoplastic based automotive bumpers and bars with modified friction stir welding(MFSW)process.For MFSW,consumable tool of polyamide6(PA6)composite has been used for joining of acrylonitrile butadiene styrene(ABS)composites.The dissimilar thermoplastics were processed for maintaining a useful range of melt flow properties followed by preparation of feed stock filament for fused deposition modeling(FDM)process through screw extrusion.Finally,3D printed PA6 based consumable rapid tool(RT)was prepared for MFSW.The joints prepared were subjected to flexural,hardness,morphological and thermal testing.The study has suggested the that maximum mechanical strength was obtained for sample welded at 1400 r/min,50 mm/min transverse speed and 3 mm plunge depth,whereas the minimum mechanical strength was obtained for sample welded at 1000 r/min,30 mm/min transverse speed and 2 mm plunge depth.The results are also supported with thermal analysis and photomicrographs.
基金PTU Jalandhar,Manufacturing Research Lab GNDEC,Ludhiana and DST GOI for financial support
文摘Fused deposition modeling(FDM) is one of the latest rapid prototyping techniques in which parts can be manufactured at a fast pace and are manufactured with a high accuracy. This research work is carried out to study the friction and wear behavior of parts made of newly developed Nylon6-Fe composite material by FDM. This work also involves the comparison of the friction and wear characteristics of the Nylon6-Fe composite with the existing acrylonitrile butadiene styrene(ABS) filament of the FDM machine. This Is carried out on the pin on disk setup by varying the load(5, 10, 15 and 20 N) and speed(200 and 300 r/min). It is concluded that the newly developed composite is highly wear resistant and can be used in industrial applications where wear resistance is of paramount importance. Morphology of the surface in contact with the Nylon6-Fe composite and ABS is also carried out.
基金Guru Nanak at Dev Engg. College, Ludhiana (GNDEC) and SERB (File No. IMRC/AISTDF/R&D/P-10/2017) for providing financial/technical assistance to carry out the research
文摘The present study reports investigations on rheological,mechanical,thermal,tribological and morphological properties of feedstock filaments prepared with polylactic acid-polyether ketone ketone-hydroxyapatite-chitosan(PLA-PEKK-HAp-CS)composite for 3D printing of functional prototypes.The study consists of a series of melt processing operations on melt flow index(MFI)setup as per ASTM D-1238 for melt flow certainty followed by fixation of reinforcement composition/proportion as 94%PEKK-4%HAp-2%CS(B)by mass in PLA matrix(A).The blending of reinforcement and preparation of feedstock filament for fused deposition modeling(FDM)set up has been performed on commercial twin screw extruder(TSE).The results of study suggest that feedstock filaments prepared with blend of 95%A-5%B(by mass)at 200℃processing temperature and 100 r/min rotational speed on TSE resulted into better tensile properties(35.9 MPa peak strength and 32.3 MPa break strength)with 6.24%surface porosity,42.67 nm surface roughness(R_(a))and acceptable heat capacity(2.14 J/g).However as regards to tribological behavior,the minimum wear of 316μm was observed for sample with poor tensile properties.As regards to crash application for scaffolds the maximum toughness of 1.16 MPa was observed for 85%A-15%B(by mass)at 200℃processing temperature and 150 r/min rotational speed on TSE.
基金supported by National Institutes of Health(NIH)grants NIH-NIAID R21 AI135457 and AI163423,1S10OD026726 and USDA-NIFA,GRANT13066347thank the Terry Johnson Cancer Research Center of Kansas State University and K-INBRE(NIH Grant P20GM103418)programs for supporting NMR studies.Contribution number 22-200-J from the Kansas Agricultural Experiment Station.
文摘Infections by mosquito-borne diseases represent one of the leading causes of death in third world countries.The rapid progression of resistance to conventional insecticide causes a significant threat to the highly efficient preventive methods currently in place.Insect neuropeptidergic system offers potential targets to control the insect vectors.The essential roles of the neuropeptide ecdysis triggering hormone(ETH)in insect development and reproduction led us to attempt understanding of the fundamentals of the biochemical interaction between ETH and its receptor in the African malaria mosquito Anopheles gambiae.One of two ETH peptides of the African malaria mosquito(AgETH1),a small peptide hormone with 17 amino acid residues(SESPGFFIKLSKSVPRI-NH2),was studied to elucidate its molecular structure.N-termini deletions and mutations of conserved amino acids in the ligand revealed the critical residues for the receptor activation.The solution structure of AgETH1 using 2D 1H-1H nuclear magnetic resonance(NMR)spectroscopy and nuclear overhauser effect(NOE)derived constraints revealed a short alpha helix between residues 3S and 11S.The NMR solution structure of AgETH1 will be of significant assistance for designing a new class of insecticidal compounds that acts on the AgETH receptor aiming for in silico docking studies.