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Metabolism of Deltamethrin in Rats
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作者 s.el-maghraby 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2007年第3期212-216,共5页
Objective To study the metabolism of 14^C-deltamethrin in rats. Methods Rats were dosed orally and i.p. with a single dose of 14^C-deltamethrin (0.64 mg/Kg) body weight. The required dose was applied daily for 3 day... Objective To study the metabolism of 14^C-deltamethrin in rats. Methods Rats were dosed orally and i.p. with a single dose of 14^C-deltamethrin (0.64 mg/Kg) body weight. The required dose was applied daily for 3 days. At the end of the experiment, selected organs, such as liver, kidney, fat, intestine, and blood were excised for radioassay of 14^C-content. Results Deltamethrin was almost eliminated from the body within 1-3 days. The main portion of 14^C-residues was extracted from urine (38%, 32%) and feces (20%, 24%) with a little amount remained in various organs. Conclusion The elimination and distribution of 14^C-radioactivity in rats treated orally and intraperitoneally signify that deltamethrin is bioavallable in urine and feces. 展开更多
关键词 Pyrethroid insecticide 14C-deltamethrin Oral and intraperitoneally treatment BIOAVAILABILITY
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