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线粒体疾病患儿神经影像学表现与线粒体呼吸链缺陷的相关性研究
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作者 J. Kim s.k. lee +5 位作者 E.Y. Kim D.I. Kim Y.M. lee J.S. lee 郭雪梅(译) 唐光健(校) 《国际医学放射学杂志》 2008年第5期423-423,共1页
线粒体疾病是影响能量代谢的一组多种表现的疾病,可在任何年龄发病,临床症状多样。观察了40例线粒体呼吸链(mitochondrial respiratory chain,MRC)缺陷综合征患儿的脑MRI表现,研究其与MRC缺陷种类的关系。40例MRC缺陷的患儿入选... 线粒体疾病是影响能量代谢的一组多种表现的疾病,可在任何年龄发病,临床症状多样。观察了40例线粒体呼吸链(mitochondrial respiratory chain,MRC)缺陷综合征患儿的脑MRI表现,研究其与MRC缺陷种类的关系。40例MRC缺陷的患儿入选,均进行了肌肉标本生化酶分析。21例患儿为经典的线粒体疾病综合征,19例患儿为非特异性线粒体脑肌病。回顾分析其脑MRI影像,并与MRC缺陷综合征的生化缺陷进行相关分析。由于复杂的基因背景和多种疾病表现型,MRC缺陷患儿的脑MRI影像具有多种神经影像学表现。 展开更多
关键词 MRI 线粒体疾病
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与独立的儿科医院比较入住围生中心将改善的早产儿结局
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作者 Shah P.S. Shah V. +1 位作者 s.k. lee 李丹 《世界核心医学期刊文摘(儿科学分册)》 2005年第10期54-55,共2页
Objectives: To examine whether admission hospital type (13 perinatal centers v s 4 freestanding pediatric hospitals) was associated with differences in risk an d illness severity adjusted mortality and morbidity among... Objectives: To examine whether admission hospital type (13 perinatal centers v s 4 freestanding pediatric hospitals) was associated with differences in risk an d illness severity adjusted mortality and morbidity among outborn preterm infant s. Study design: Records of singleton outborn infants ≤32 weeks’gestational ag e (n = 605) admitted to 17 tertiary level neonatal intensive care units particip ating in the Canadian Neonatal Network for the period 1996 to 1997 were examined . Results: Outborn infants admitted to freestanding pediatric hospitals were at higher risk of death (adjusted odds ratio [AOR], 2.25; 95%confidence interval [ CI], 1.20, 4.20), nosocomial infection (AOR, 2.48; 95%CI, 1.64, 3.73), and oxyg en dependency at 28 days of age (AOR, 1.77; 95%CI, 1.14, 2.75) when compared wi th outborn infants admitted to perinatal centers. Conclusions: After adjustment for perinatal risks and admission illness severity, outborn infants had better o utcomes if they were admitted to perinatal centers compared with freestanding pe diatric hospitals. 展开更多
关键词 儿科医院 医疗记录 疾病严重程度 出生婴儿 院内感染率 围生期 优势比 研究设计
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