Left sided valvular heart disease poses major impact on life and lifestyle.Medical therapy merely palliates chronic severe valve disease and once symptoms or haemodynamic sequelae appear,life expectancy is markedly tr...Left sided valvular heart disease poses major impact on life and lifestyle.Medical therapy merely palliates chronic severe valve disease and once symptoms or haemodynamic sequelae appear,life expectancy is markedly truncated.In this article,we review the mechanisms of valve pathology,latest evidence in the quest for pharmacological options,means by which to predict deterioration,and standard and novel treatment options.展开更多
文摘Left sided valvular heart disease poses major impact on life and lifestyle.Medical therapy merely palliates chronic severe valve disease and once symptoms or haemodynamic sequelae appear,life expectancy is markedly truncated.In this article,we review the mechanisms of valve pathology,latest evidence in the quest for pharmacological options,means by which to predict deterioration,and standard and novel treatment options.
