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A Novel Rodent Model Modifying Perioperative Temperature and Humidity during Bowel Surgery and Mimicking Laparoscopic Conditions
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作者 Torben Glatz Gabriel Seifert +6 位作者 Philipp AHolzner schikhladze Birte Kulemann Olivia Sick Jens Hoppner Ulrich Theodor Hopt Goran Marjanovic 《Surgical Science》 2012年第7期353-357,共5页
Laparoscopic surgery seems to have a general physiological benefit compared to conventional procedures in several clincal studies especially regarding intestinal anastomotic healing. Reliable experimental data concern... Laparoscopic surgery seems to have a general physiological benefit compared to conventional procedures in several clincal studies especially regarding intestinal anastomotic healing. Reliable experimental data concerning the particular mode of beneficial action are lacking. Clinical studies will not be able to identify the variables responsible for this effect. To establish a feasible, standardized experimental model to investigate variables such as humidity and perioperative room temperature, we employed an incubator designed for neonatal care. This allows individual manipulation and observation of above mentioned variables. Our initial results show that creating intestinal anastomoses in the incubator is safe and easy to perform, creating a valuable possibility to influence perioperative conditions for experimental and clinical research. 展开更多
关键词 Intestinal Anastomosis Anastomotic Leak LAPAROSCOPY INCUBATOR Rat
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