In this paper, a novel compound 3-（2-qninolyl）-5-ferrocenyl-isoxazole（5） with high selectivity toward Cu2＋ over other heavy and transition-metal（HTM） ions was designed and synthesized in good yields. The compou...In this paper, a novel compound 3-（2-qninolyl）-5-ferrocenyl-isoxazole（5） with high selectivity toward Cu2＋ over other heavy and transition-metal（HTM） ions was designed and synthesized in good yields. The compound not only could be used as an electrochemical probe for Cu2＋ with an anodic peak shift of Fe（II）/Fe（III） redox couple, but also could be a colorimetric and fluorescent probe due to the detectable change in color by naked eyes and a significant fluorescence quenching of monomeric anthracene moiety. This highly selective sensing of Cu2＋ may be attributed to the unprecedented intermolecular electron-transfer reorganization after the oxidation of the first single electron of compound 5, as indicated by electrospray ionization mass spectrometry（ESI-MS） and density functional theory（DFT） calculation results. To the best of our knowledge, this class of compounds have rarely been reported in the field of molecular sensing. It may have a potential significance for the application of the ferrocenyl-isoxazole derivative in molecular recognition.展开更多
A facile and efficient synthesis of N-sulfonyl-N,N-disubstituted amidines has been achieved via a CuI-catalyzed three-component free-radical coupling reaction of tertiary amines and arenesulfonyl azides with terminal ...A facile and efficient synthesis of N-sulfonyl-N,N-disubstituted amidines has been achieved via a CuI-catalyzed three-component free-radical coupling reaction of tertiary amines and arenesulfonyl azides with terminal alkynes in the presence of azodiisobutyronitrile(AIBN).The reaction mechanism of this reaction has also been studied.展开更多
A convenient and efficient method was developed for the synthesis of 2,2＇-（arylmethylene）bis（3-hydrox- ycyclohex-2-enone） derivatives via the oleylamine-catalyzed tandem Knoevenagel/Michael addition reactions of ...A convenient and efficient method was developed for the synthesis of 2,2＇-（arylmethylene）bis（3-hydrox- ycyclohex-2-enone） derivatives via the oleylamine-catalyzed tandem Knoevenagel/Michael addition reactions of aromatic aldehydes and cyclohexane-1,3-diones. This transformation proceeded without any metal catalyst in non-toxic solvent at room temperature with high isolated yields. A plausible mechanism for this process was pro- posed.展开更多
A convenient and efficient method was developed for the synthesis of naphtho[2,1-blfurans via 4-dimethylaminopyridine（DMAP）-catalyzed cascade reaction of 2-hydroxy-l-naphthaldehydes and a-halogenated ketones in mode...A convenient and efficient method was developed for the synthesis of naphtho[2,1-blfurans via 4-dimethylaminopyridine（DMAP）-catalyzed cascade reaction of 2-hydroxy-l-naphthaldehydes and a-halogenated ketones in moderate to good yields in the presence of Na2CO3 at 80 ~C for 6 h. The mechanism for this process was briefly discussed with a tentative catalytic cycle proposed. Moreover, this method features organocatalysts and high step-economy, which makes it practical and attractive.展开更多
基金Supported by the National Natural Science Foundation of China（Nos.21172001, 21372008）, the Natural Science Foundation of the Education Administration of Anhni Province, China（No.K J2016A267）, the Special and Excellent Research Fund of Anhui Normal University, China and the Doctoral Scientific Research Foundation of Anhui Normal University, China（No.2016XJJ110）.
文摘In this paper, a novel compound 3-（2-qninolyl）-5-ferrocenyl-isoxazole（5） with high selectivity toward Cu2＋ over other heavy and transition-metal（HTM） ions was designed and synthesized in good yields. The compound not only could be used as an electrochemical probe for Cu2＋ with an anodic peak shift of Fe（II）/Fe（III） redox couple, but also could be a colorimetric and fluorescent probe due to the detectable change in color by naked eyes and a significant fluorescence quenching of monomeric anthracene moiety. This highly selective sensing of Cu2＋ may be attributed to the unprecedented intermolecular electron-transfer reorganization after the oxidation of the first single electron of compound 5, as indicated by electrospray ionization mass spectrometry（ESI-MS） and density functional theory（DFT） calculation results. To the best of our knowledge, this class of compounds have rarely been reported in the field of molecular sensing. It may have a potential significance for the application of the ferrocenyl-isoxazole derivative in molecular recognition.
基金National Natural Science Foundation of China (20872001)the Anhui Education Department (TD200707 & KJ2008A064)+1 种基金the Program for the NCET (NCET-10-0004)the Research Culture Funds of Anhui Normal University (2010rcpy041) for their financial support
文摘A facile and efficient synthesis of N-sulfonyl-N,N-disubstituted amidines has been achieved via a CuI-catalyzed three-component free-radical coupling reaction of tertiary amines and arenesulfonyl azides with terminal alkynes in the presence of azodiisobutyronitrile(AIBN).The reaction mechanism of this reaction has also been studied.
基金Supported by the National Natural Science Foundation of China（Nos.21772001, 21372008）, the Natural Science Foundation of Education Administration of Anhui Province, China（No.KJ2016A267）, the Special and Excellent Research Fund of Anhui Normal Universit and the Doctoral Scientific Research Foundation of Anhui Normal University, China（No.2016XJJ110）.
文摘A convenient and efficient method was developed for the synthesis of 2,2＇-（arylmethylene）bis（3-hydrox- ycyclohex-2-enone） derivatives via the oleylamine-catalyzed tandem Knoevenagel/Michael addition reactions of aromatic aldehydes and cyclohexane-1,3-diones. This transformation proceeded without any metal catalyst in non-toxic solvent at room temperature with high isolated yields. A plausible mechanism for this process was pro- posed.
基金Supported by the National Natural Science Foundation of China（Nos.21172001, 21372008）, the Program for the New Century Excellent Talents in University of China（No.NCET-10-0004） and the Natural Science Foundation of Anhui Province of China（No. 1308085QB39）.
文摘A convenient and efficient method was developed for the synthesis of naphtho[2,1-blfurans via 4-dimethylaminopyridine（DMAP）-catalyzed cascade reaction of 2-hydroxy-l-naphthaldehydes and a-halogenated ketones in moderate to good yields in the presence of Na2CO3 at 80 ~C for 6 h. The mechanism for this process was briefly discussed with a tentative catalytic cycle proposed. Moreover, this method features organocatalysts and high step-economy, which makes it practical and attractive.
