The 21st century is the era of marine economy.The Chinese government attaches great importance to the development and utilization of marine resources.With the support of national marine policies,the development of mar...The 21st century is the era of marine economy.The Chinese government attaches great importance to the development and utilization of marine resources.With the support of national marine policies,the development of marine tourism industry in Yantai has changed with each passing day,and the content of tourism products developed by Yantai is also constantly innovating.In this study,by using literature research,data analysis and other methods,the development of marine tourism resources in Yantai was analyzed.The results show that the marine tourism products in Yantai are not well-known,less competitive,and are difficult to form a scale advantage.Therefore,some measures to promote the development of tourism industry in Yantai were proposed,such as optimizing and upgrading marine tourism products in Yantai,strengthening regional cooperation to increase product awareness,improving the structure scale of products in scenic spots to enhance competitiveness,attaching importance to the application of science and technology and strengthening product innovation.展开更多
趋化因子(chemoattractant cytokine ligand,CCL)是一类可趋化细胞移动的小分子肽物质,根据其分子结构中N-末端半胱氨酸的相对位置主要分为四种类型,CCL17是其中CC型的趋化因子,也被称作胸腺和活化调节趋化因子(thymus and activation r...趋化因子(chemoattractant cytokine ligand,CCL)是一类可趋化细胞移动的小分子肽物质,根据其分子结构中N-末端半胱氨酸的相对位置主要分为四种类型,CCL17是其中CC型的趋化因子,也被称作胸腺和活化调节趋化因子(thymus and activation regulated chemokine,TARC).趋化因子通过结合细胞表面的趋化因子受体(chemokine receptor,CCR)发挥其生物学功能,CCL17对应的膜受体为CCR4分子,主要表达于多种T淋巴细胞亚群的细胞膜表面.研究发现CCL17具有多样的生物学功能,它能够趋化CCR4阳性的细胞发生迁移作用,参与到机体的炎症、超敏反应及自身免疫性疾病等多种病理生理过程,近年来有关CCL17参与肿瘤微环境及影响机体肿瘤免疫功能的研究多有报道,研究发现CCL17可能通过调节性T细胞(regulatory T cells,Treg)发挥促进肿瘤生长与转移的作用,但也有相关报道证实CCL17在特定条件下亦具有抗肿瘤免疫作用.展开更多
基金Sponsored by Scientific Research Project of Colleges and Universities in Shandong Province,China(J18KA197)Science and Technology Innovation Development Project of Tai’an(Policy Guidance)(2020ZC322)Key Project of Art Science in Shandong Province,China(ZD202008364)。
文摘The 21st century is the era of marine economy.The Chinese government attaches great importance to the development and utilization of marine resources.With the support of national marine policies,the development of marine tourism industry in Yantai has changed with each passing day,and the content of tourism products developed by Yantai is also constantly innovating.In this study,by using literature research,data analysis and other methods,the development of marine tourism resources in Yantai was analyzed.The results show that the marine tourism products in Yantai are not well-known,less competitive,and are difficult to form a scale advantage.Therefore,some measures to promote the development of tourism industry in Yantai were proposed,such as optimizing and upgrading marine tourism products in Yantai,strengthening regional cooperation to increase product awareness,improving the structure scale of products in scenic spots to enhance competitiveness,attaching importance to the application of science and technology and strengthening product innovation.
文摘趋化因子(chemoattractant cytokine ligand,CCL)是一类可趋化细胞移动的小分子肽物质,根据其分子结构中N-末端半胱氨酸的相对位置主要分为四种类型,CCL17是其中CC型的趋化因子,也被称作胸腺和活化调节趋化因子(thymus and activation regulated chemokine,TARC).趋化因子通过结合细胞表面的趋化因子受体(chemokine receptor,CCR)发挥其生物学功能,CCL17对应的膜受体为CCR4分子,主要表达于多种T淋巴细胞亚群的细胞膜表面.研究发现CCL17具有多样的生物学功能,它能够趋化CCR4阳性的细胞发生迁移作用,参与到机体的炎症、超敏反应及自身免疫性疾病等多种病理生理过程,近年来有关CCL17参与肿瘤微环境及影响机体肿瘤免疫功能的研究多有报道,研究发现CCL17可能通过调节性T细胞(regulatory T cells,Treg)发挥促进肿瘤生长与转移的作用,但也有相关报道证实CCL17在特定条件下亦具有抗肿瘤免疫作用.
