目的探讨采用临时间隔物并二期手术治疗髋、膝关节慢性化脓性关节炎的疗效。方法回顾性分析北京积水潭医院2017年1月至2019年12月期间诊断为髋关节或者膝关节化脓性关节炎并接受二期手术流程的22例病例资料,男12例,女10例;年龄34~74岁,...目的探讨采用临时间隔物并二期手术治疗髋、膝关节慢性化脓性关节炎的疗效。方法回顾性分析北京积水潭医院2017年1月至2019年12月期间诊断为髋关节或者膝关节化脓性关节炎并接受二期手术流程的22例病例资料,男12例,女10例;年龄34~74岁,平均(57.4±10.5)岁。其中髋关节化脓性关节炎患者7例,膝关节化脓性关节炎患者15例。采用Kaplan-Meier生存分析法计算患者的感染治疗成功率。比较手术前后髋关节患者Harris髋关节评分(Harris hip score,HHS)与膝关节患者美国特种外科医院(hospital for special surgery,HSS)膝关节评分,分析采用该方法的治疗效果。结果1例膝关节患者在接受手术后10个月因内科疾病死亡;1例髋关节患者在术后9个月感染复发。5例患者仅接受一期手术治疗,但随访中未出现感染复发。17例患者完成二期手术,其中15例患者达到临床治愈。治疗成功率在2年时为89.5%(95%CI:64.1%~97.3%)。髋关节组患者HHS评分及膝关节组患者HSS评分均较术前明显提高。结果采用临时间隔物并二期手术是治疗慢性髋、膝关节化脓性关节炎的有效方法,可以获得较高的感染控制率,同时可以有效地重建关节功能。展开更多
As continuous of the previous sand-dune-inspired design,the Barchan-Dune-Shaped Injection Compound(BDSIC)’s film cooling performance at the endwall region was further investigated both experimentally and numerically....As continuous of the previous sand-dune-inspired design,the Barchan-Dune-Shaped Injection Compound(BDSIC)’s film cooling performance at the endwall region was further investigated both experimentally and numerically.While the public 777-shaped hole was served as a baseline,the BDSIC’s endwall effectiveness was assessed at various blowing ratios.Experiments were performed in a single-passage transonic wind tunnel using pressure-sensitive paint(PSP)technique.Carbon dioxide was used as coolant with density ratio of DR=1.53.The purge slot’s blowing ratio was fixed at M=0.3,but the coolant holes were adjusted within M=0.5–2.0.The measured experimental results indicate that the film distribution at the endwall is strongly affected by the passage flow structures.The BDSIC holes demonstrate much higher film effectiveness than the 777-shaped holes for all blowing ratios,~30%enhancement for regionally averaged effectiveness at M=1.0 and~26%at M=2.0.As shown by the numerical results,the existence of BDSIC reduced the coolant penetration effect at a higher blowing ratio.Coolant was deflected and its momentum increased in the streamwise direction,therefore providing more robust film coverage over the endwall region.The anti-counter-rotating vortex pair induced by the BDSIC further stabilized the coolant film and increased the coolant spreading downstream.展开更多
文摘目的探讨采用临时间隔物并二期手术治疗髋、膝关节慢性化脓性关节炎的疗效。方法回顾性分析北京积水潭医院2017年1月至2019年12月期间诊断为髋关节或者膝关节化脓性关节炎并接受二期手术流程的22例病例资料,男12例,女10例;年龄34~74岁,平均(57.4±10.5)岁。其中髋关节化脓性关节炎患者7例,膝关节化脓性关节炎患者15例。采用Kaplan-Meier生存分析法计算患者的感染治疗成功率。比较手术前后髋关节患者Harris髋关节评分(Harris hip score,HHS)与膝关节患者美国特种外科医院(hospital for special surgery,HSS)膝关节评分,分析采用该方法的治疗效果。结果1例膝关节患者在接受手术后10个月因内科疾病死亡;1例髋关节患者在术后9个月感染复发。5例患者仅接受一期手术治疗,但随访中未出现感染复发。17例患者完成二期手术,其中15例患者达到临床治愈。治疗成功率在2年时为89.5%(95%CI:64.1%~97.3%)。髋关节组患者HHS评分及膝关节组患者HSS评分均较术前明显提高。结果采用临时间隔物并二期手术是治疗慢性髋、膝关节化脓性关节炎的有效方法,可以获得较高的感染控制率,同时可以有效地重建关节功能。
基金funding supports from the NSFC(92052107,51806138)。
文摘As continuous of the previous sand-dune-inspired design,the Barchan-Dune-Shaped Injection Compound(BDSIC)’s film cooling performance at the endwall region was further investigated both experimentally and numerically.While the public 777-shaped hole was served as a baseline,the BDSIC’s endwall effectiveness was assessed at various blowing ratios.Experiments were performed in a single-passage transonic wind tunnel using pressure-sensitive paint(PSP)technique.Carbon dioxide was used as coolant with density ratio of DR=1.53.The purge slot’s blowing ratio was fixed at M=0.3,but the coolant holes were adjusted within M=0.5–2.0.The measured experimental results indicate that the film distribution at the endwall is strongly affected by the passage flow structures.The BDSIC holes demonstrate much higher film effectiveness than the 777-shaped holes for all blowing ratios,~30%enhancement for regionally averaged effectiveness at M=1.0 and~26%at M=2.0.As shown by the numerical results,the existence of BDSIC reduced the coolant penetration effect at a higher blowing ratio.Coolant was deflected and its momentum increased in the streamwise direction,therefore providing more robust film coverage over the endwall region.The anti-counter-rotating vortex pair induced by the BDSIC further stabilized the coolant film and increased the coolant spreading downstream.
