质子转移反应质谱(Proton Transfer Reaction Mass Spectrometer,PTR-MS)是一种快速高灵敏的挥发性有机物检测技术。国产PTR-MS自2008年建成以来,已经在部分技术和应用领域达到国际先进水平。本文首先介绍了仪器原理,阐明了待测物离子...质子转移反应质谱(Proton Transfer Reaction Mass Spectrometer,PTR-MS)是一种快速高灵敏的挥发性有机物检测技术。国产PTR-MS自2008年建成以来,已经在部分技术和应用领域达到国际先进水平。本文首先介绍了仪器原理,阐明了待测物离子化、传输、探测过程中的主要影响因素。然后展示了国产PTR-MS的产品线,主要包括质子反转移反应质谱仪、双极性质子转移反应质谱仪、呼气检测仪、船载液体进样质谱仪、车载大气走航监测质谱仪、快速色谱-质子转移反应质谱仪等,部分产品已经实现了批量生产和销售。技术发展方面,在灵敏度提升和多反应离子制备上取得了重要进展。最后介绍了国产PTR-MS在环境、医学、安全等领域的应用,比如大气污染溯源、人体呼气中疾病标志物的发掘、爆炸物快检等。同时,展望了国产PTR-MS的发展方向和应用前景。展开更多
Real-time and on-line monitoring volatile organic compounds（VOCs） are valuable for real-time evalua- ting air quality and monitoring the key source of pollution. A self-developed proton transfer reaction-mass spectr...Real-time and on-line monitoring volatile organic compounds（VOCs） are valuable for real-time evalua- ting air quality and monitoring the key source of pollution. A self-developed proton transfer reaction-mass spectro- meter（PTR-MS） was constructed and applied to on-line monitoring trace VOCs in ambient air in Hefei, China. With the help of a self-developed catalytic converter, the background signal of the instrument was detected and the stability of the instrument was evaluated. The relative standard deviation of signal at m/z 21 was only 0.74% and the detection limit of PTR-MS was 97 part per trillion（97x 10-12, volume ratio）. As a case of the air monitoring in Hefei, the am- bient air at Dongpu reservoir spot was on-line monitored for 13 d with our self-developed PTR-MS. Meanwhile, a solid-phase micro-extraction（SPME） technique coupled to gas chromatography-mass spectrometry/mass spectrometry （GC-MS/MS） was also used for the off-line detection of the air. The results show that our self-developed PTR-MS can be used for the on-line and long-term monitoring of VOCs in air at part per trillion level, and the change trend of VOCs concentration monitored with PTR-MS was consistent with that detected with the conventional SPME-GC-MS. This self-developed PTR-MS can fully satisfy the requirements of air quality monitoring and real-time monitoring of the key pollution sources.展开更多
文摘质子转移反应质谱(Proton Transfer Reaction Mass Spectrometer,PTR-MS)是一种快速高灵敏的挥发性有机物检测技术。国产PTR-MS自2008年建成以来,已经在部分技术和应用领域达到国际先进水平。本文首先介绍了仪器原理,阐明了待测物离子化、传输、探测过程中的主要影响因素。然后展示了国产PTR-MS的产品线,主要包括质子反转移反应质谱仪、双极性质子转移反应质谱仪、呼气检测仪、船载液体进样质谱仪、车载大气走航监测质谱仪、快速色谱-质子转移反应质谱仪等,部分产品已经实现了批量生产和销售。技术发展方面,在灵敏度提升和多反应离子制备上取得了重要进展。最后介绍了国产PTR-MS在环境、医学、安全等领域的应用,比如大气污染溯源、人体呼气中疾病标志物的发掘、爆炸物快检等。同时,展望了国产PTR-MS的发展方向和应用前景。
基金Supported by the National Natural Science Foundation of China（Nos.21477132, 21577145）, the National Key Technology Research and Development Program of China（No.2015BAI01B04）, the National Key Research Program of China （No.2016YFC0200200）, the Innovative Program of Development Foundation of Hefei Center for Physical Science and Technology of China（No.2014FXCX007） and the Functional Development Program of Instrument and Equipment in Chinese Academy of Sciences.
文摘Real-time and on-line monitoring volatile organic compounds（VOCs） are valuable for real-time evalua- ting air quality and monitoring the key source of pollution. A self-developed proton transfer reaction-mass spectro- meter（PTR-MS） was constructed and applied to on-line monitoring trace VOCs in ambient air in Hefei, China. With the help of a self-developed catalytic converter, the background signal of the instrument was detected and the stability of the instrument was evaluated. The relative standard deviation of signal at m/z 21 was only 0.74% and the detection limit of PTR-MS was 97 part per trillion（97x 10-12, volume ratio）. As a case of the air monitoring in Hefei, the am- bient air at Dongpu reservoir spot was on-line monitored for 13 d with our self-developed PTR-MS. Meanwhile, a solid-phase micro-extraction（SPME） technique coupled to gas chromatography-mass spectrometry/mass spectrometry （GC-MS/MS） was also used for the off-line detection of the air. The results show that our self-developed PTR-MS can be used for the on-line and long-term monitoring of VOCs in air at part per trillion level, and the change trend of VOCs concentration monitored with PTR-MS was consistent with that detected with the conventional SPME-GC-MS. This self-developed PTR-MS can fully satisfy the requirements of air quality monitoring and real-time monitoring of the key pollution sources.
