Improving structures involves comparing old and new designs on a key parameter.Calculating the percent change in performance is a method to assess.This paper proposes a cost-effective analogy by generating replicas of...Improving structures involves comparing old and new designs on a key parameter.Calculating the percent change in performance is a method to assess.This paper proposes a cost-effective analogy by generating replicas of additive manufactured aluminum alloy(Al Si10Mg)body-centered cubic lattice(BCC)based turbine blade(T106C)with the same in poly-lactic acid(PLA)material and their comparison in the context of percent change for natural frequencies.Initially,a cavity is created inside the turbine blade(hollow blade).Natural frequencies are obtained experimentally and numerically by incorporating BCC at 50%and 80%of the cavity length into the hollow blade for both materials.The cost of manufacturing the metal blades is 90%more than that of the PLA blades.The two material blade designs show a similar percentage variation,as the first-order mode enhancs more than 5%and the second-order mode more than 4%.To observe the behavior in another material,both blades are analyzed numerically with a nickel-based U-500 material,and the same result is achieved,describing that percent change between designs can be verified using the PLA material.展开更多
基金The work was supported by the National Natural Science Foundation of China(No.52305262)the Starting Grant of Nanjing University of Aeronautics and Astronautics(No.1001-YQR22056).
基金supported by the National Natural Science Foundation of China(No.12111540251)。
文摘Improving structures involves comparing old and new designs on a key parameter.Calculating the percent change in performance is a method to assess.This paper proposes a cost-effective analogy by generating replicas of additive manufactured aluminum alloy(Al Si10Mg)body-centered cubic lattice(BCC)based turbine blade(T106C)with the same in poly-lactic acid(PLA)material and their comparison in the context of percent change for natural frequencies.Initially,a cavity is created inside the turbine blade(hollow blade).Natural frequencies are obtained experimentally and numerically by incorporating BCC at 50%and 80%of the cavity length into the hollow blade for both materials.The cost of manufacturing the metal blades is 90%more than that of the PLA blades.The two material blade designs show a similar percentage variation,as the first-order mode enhancs more than 5%and the second-order mode more than 4%.To observe the behavior in another material,both blades are analyzed numerically with a nickel-based U-500 material,and the same result is achieved,describing that percent change between designs can be verified using the PLA material.
文摘目的探究绿原酸(chlorogenic acid,CGA)氧化形成的CGA醌与氨基酸侧链基团在不同pH条件下的反应效率,为CGA与蛋白质共价互作反应位点的调控提供理论依据。方法利用循环伏安法研究了酸性(pH 5.0)、中性(pH 7.0)和碱性(pH 8.0)条件下CGA与氨基酸侧链基团的反应效率,采用超高效液相色谱-四极杆飞行时间串联质谱法(ultra performance liquid chromatography-quadrupole time of flight-tandem mass spectrometry,UPLC-QTOF-MS/MS)对反应产物进行结构鉴定。结果在pH7.0、扫描速率10mV/s,0.20mmol/LCGA与10.00mmol/L封闭α-氨基的氨基酸的反应效率依次为Nα-乙酰-L-半胱氨酸(~100.00%)≈Nα-乙酰-L-色氨酸(~100.00%)>Nα-乙酰-L-酪氨酸(39.20%±2.19%)>Nα-乙酰-L-赖氨酸(10.25%±0.83%)>Nα-boc-L-组氨酸(~0.00%)≈Nα-乙酰-L-精氨酸(~0.00%);在其他反应条件相同的情况下,缩小扫描电压范围至-0.4~0.4V,CGA与Nα-乙酰-L-半胱氨酸、Nα-乙酰-L-色氨酸及Nα-乙酰-L-酪氨酸的共价互作效率分别为~100%、12.83%±1.16%及~0%;pH 7.0或8.0时,GCA与氨基酸残基的共价互作效率高于pH 5.0;CGA醌与Nα-乙酰-L-赖氨酸、Nα-乙酰-L-精氨酸的反应产物以氧化态的醌-氨基酸形式存在,而CGA醌与Nα-乙酰-L-半胱氨酸、Nα-boc-L-组氨酸、Nα-乙酰-L-色氨酸的反应产物以还原态的酚-氨基酸形式存在。结论CGA氧化形成的CGA醌可与蛋白质中半胱氨酸、色氨酸、赖氨酸、组氨酸及精氨酸残基发生反应,其中半胱氨酸残基是CGA醌与蛋白质共价互作的主要位点,可通过调整食品体系的pH和绿原酸醌浓度实现绿原酸-蛋白质共价互作位点的调控。
