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儿童神经节细胞瘤及神经节神经母细胞瘤混杂型的治疗经验
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作者 郑曼娜 李嘉豪 +13 位作者 李乐 谭天宝 潘静 胡超 杨纪亮 沈远超 吴慧莹 牛会林 徐涛 张晓红 陈希文 鹿连伟 邹焱 杨天佑 《中国小儿血液与肿瘤杂志》 CAS 2023年第2期113-117,共5页
目的总结治疗儿童神经节细胞瘤及神经节神经母细胞瘤混杂型的经验。方法回顾性分析2009年5月—2019年11月在广州市妇女儿童医疗中心诊治的神经节细胞瘤及神经节神经母细胞瘤混杂型病例。采用Mann-Whitney U检验、卡方检验和费希尔精确... 目的总结治疗儿童神经节细胞瘤及神经节神经母细胞瘤混杂型的经验。方法回顾性分析2009年5月—2019年11月在广州市妇女儿童医疗中心诊治的神经节细胞瘤及神经节神经母细胞瘤混杂型病例。采用Mann-Whitney U检验、卡方检验和费希尔精确检验进行比较各指标,采用Kaplan-Meier进行生存分析、Log-rank比较生存曲线。结果本研究共纳入88例患儿,中位年龄为54.7(13.7~192.0)个月。肿瘤原发于颈部(2例)、胸部(54例)、胸腹(2例)、腹部(24例)、盆腔(6例)。INSS分期1期、2A、2B、3期、4期分别为58例、9例、10例、9例、2例。所有患儿均接受手术切除,术中失血量中位数为50(2~4700)mL,术中输注红细胞中位数为1.(0~7)单位、输注血浆中位数为100(0~1700)mL。5例(5.7%)患儿发生了并发症。20例(22.7%)有肿瘤残留,其中11例肿瘤残留大于2cm,2例残留小于2cm,另外7例未记录具体残留组织大小。术后病理确诊神经节细胞瘤32例(36.4%),神经节神经母细胞瘤混杂型56例(63.6%)。神经节细胞瘤患儿发病年龄较神经节神经母细胞瘤混杂型患儿大[69.1(47.4~88.3)个月vs 49.6(32.1~68.9)个月,P=0.005]。中位随访时间为23.5(0.0~89.0)个月,2例(2.3%)复发、3例(3.4%)死亡、9例(10.2%)失访。术后肿瘤残留对无事件生存率及总体生存率没有显著影响(P=0.691,P=0.128)。结论神经节细胞瘤及神经节神经母细胞瘤混杂型总体治疗效果良好,手术治疗安全有效,术后肿瘤残留对临床结局可能无显著影响。 展开更多
关键词 神经节细胞瘤 神经节神经母细胞瘤混杂型 儿童 手术
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Locating Mechanism of Quartz Vein Gold Deposits in Rushan, Shandong Province
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作者 XIE Hongyuan shen yuanchao +4 位作者 WANG Yuejun LI Guangming LIU Tiebing ZHANG Qirui ZEN Qingdong 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 1998年第1期77-86,共10页
According to the differences in ore-controlling structural systems and the characteristics of host rocks, textures and structures of ores and mineral associations of ores, quartz vein-type gold deposits in the Rushan ... According to the differences in ore-controlling structural systems and the characteristics of host rocks, textures and structures of ores and mineral associations of ores, quartz vein-type gold deposits in the Rushan area can be divided into the Rushan and Tongling styles. Rushan style gold deposits, occurring in the Kunyushan complex, include Rushan, Tangjiagou and Tongxishan gold mines. They are distributed along four NNE-trending and sinistral, compresso-shear faults with a right stepping array. A prominent characteristic of the gold mineralization is that the orebodies in neighbouring gold deposits distributed in a single ore-controlling fault zone take opposite pitches. Study of the locating structures of the quartz vein gold deposits shows that the Rushan-style gold deposits are characterized by NNE and NE zoning. Therefore, the intersections of the NE direction of the known gold deposit and the neighbouring NNE-trending fault zones are favourable for looking for gold deposits, and the ends of the curving segments of sinistral and right-stepping faults are favourable for looking for large gold deposits. Tongling-style gold deposits occur in the Sanfosan porphyritic monzonitic granite. Emplacement of gold deposits is controlled by arcuate and radiate structures formed during the intrusion of the Sanfoshan porphyritic monzonitic granite; the radiate faults controlled the distribution of orebodies and the arcuate faults controlled the pitch of the orebodies. 展开更多
关键词 vein type gold deposit Muping-Rushan gold mineralized zone conjugate orebodies arcuate and radiate structures
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