Objective To investigate the association of retinal vascular calibers with hyperuricemia in a middle‐aged and elderly population. Methods A cross‐sectional design was applied in this study and 869 participants aged ...Objective To investigate the association of retinal vascular calibers with hyperuricemia in a middle‐aged and elderly population. Methods A cross‐sectional design was applied in this study and 869 participants aged ≥40 years from a high‐risk group for diabetes were recruited. All participants received the anthropometrical measurements and laboratory tests. Retinal arteriolar and venular caliber of the participants were measured with a semi‐automated system. Hyperuricemia was defined as a serum uric acid level 420 μmol/L in men and 360 μmol/L in women. Linear regression models were used to assess the association of hyperuricemia with retinal vascular calibers. These models were additionally adjusted for age, central obesity, hypertension, dyslipidemia, weekly activity, smoking status, and education. Results Among the 869 participants, 133 （15.3%） suffered from hyperuricemia. The crude mean serum uric acid level was 312.3 μmol/L （Standard Deviation 79.5）; mean concentration was 355.0 μmol/L （SD 75.5） in male participants, and 288.0 μmol/L （SD 71.1） in female participants （age‐adjusted difference 58.1 μmol/L, 95% Confidence Internal 48.5, 67.6）. After adjusting for additional covariates, male participants with hyperuricemia had 3.77 μm （95% CI ‐0.46, 8.00） smaller arteriolar caliber and 6.20 μm （95% CI 0.36, 12.04） larger venule than those without hyperuricemia; the corresponding numbers among female participants were 1.57 μm （95% CI ‐1.07, 4.21） for retinal arteriolar caliber and 2.28 μm （95% CI ‐1.72, 6.27） for retinal venular caliber. Conclusion Hyperuricemia was associated with smaller retinal arteriolar caliber and larger venular caliber mainly in male participants in this study.展开更多
The South Narimalahei area is located on the north side of the Middle Kunlun fault in the eastern section of the East Kunlun composite orogenic belt. The ore body is veined and controlled by structures and se- condary...The South Narimalahei area is located on the north side of the Middle Kunlun fault in the eastern section of the East Kunlun composite orogenic belt. The ore body is veined and controlled by structures and se- condary fissures, which occurs in the structural alteration fracture zone in the Late Triassic granodiorite. In this deposit, copper mineralization is closely related to silicification and sericification. The formation process of the deposit includes hydrothermal mineralization and supergene oxidation. In this paper, the fluid inclusion minera- logy , microscopic temperature measurement and stable isotope studies have been carried out for ore of the main mineralization stage. The results show that the primary gas-liquid two-phase inclusions and a small amount of single-liquid inclusions are mainly developed in the quartz in the main mineralization stage. The results of microscopic temperature measurement show that the ore-forming fluid which has low temperature (151.7℃ -205.8 ℃), low salinity(2.06wt% - 4.94wt%NaCl), low density (0.86 -0.92 g/cm^( 3)) and shallow formation (1.5 -3.0 km) is a hydrothermal solution of NaCl-H_(2)O system. Hydrogen and oxygen isotope results show that the ore-forming fluids mainly come from atmospheric precipitation, with a small amount of magmatic fluids participating. It is preliminarily determined that the South Narimalahei copper polymetallic deposit is a low- temperature hydrothermal vein deposit.展开更多
基金supported by Science and Technology Commission of Shanghai Municipality (STCSM) and the Key Project of Health Bureau of Shanghai (Grant 04dz19501‐1 and 08GWZX0203 to Xin GAO)
文摘Objective To investigate the association of retinal vascular calibers with hyperuricemia in a middle‐aged and elderly population. Methods A cross‐sectional design was applied in this study and 869 participants aged ≥40 years from a high‐risk group for diabetes were recruited. All participants received the anthropometrical measurements and laboratory tests. Retinal arteriolar and venular caliber of the participants were measured with a semi‐automated system. Hyperuricemia was defined as a serum uric acid level 420 μmol/L in men and 360 μmol/L in women. Linear regression models were used to assess the association of hyperuricemia with retinal vascular calibers. These models were additionally adjusted for age, central obesity, hypertension, dyslipidemia, weekly activity, smoking status, and education. Results Among the 869 participants, 133 （15.3%） suffered from hyperuricemia. The crude mean serum uric acid level was 312.3 μmol/L （Standard Deviation 79.5）; mean concentration was 355.0 μmol/L （SD 75.5） in male participants, and 288.0 μmol/L （SD 71.1） in female participants （age‐adjusted difference 58.1 μmol/L, 95% Confidence Internal 48.5, 67.6）. After adjusting for additional covariates, male participants with hyperuricemia had 3.77 μm （95% CI ‐0.46, 8.00） smaller arteriolar caliber and 6.20 μm （95% CI 0.36, 12.04） larger venule than those without hyperuricemia; the corresponding numbers among female participants were 1.57 μm （95% CI ‐1.07, 4.21） for retinal arteriolar caliber and 2.28 μm （95% CI ‐1.72, 6.27） for retinal venular caliber. Conclusion Hyperuricemia was associated with smaller retinal arteriolar caliber and larger venular caliber mainly in male participants in this study.
文摘The South Narimalahei area is located on the north side of the Middle Kunlun fault in the eastern section of the East Kunlun composite orogenic belt. The ore body is veined and controlled by structures and se- condary fissures, which occurs in the structural alteration fracture zone in the Late Triassic granodiorite. In this deposit, copper mineralization is closely related to silicification and sericification. The formation process of the deposit includes hydrothermal mineralization and supergene oxidation. In this paper, the fluid inclusion minera- logy , microscopic temperature measurement and stable isotope studies have been carried out for ore of the main mineralization stage. The results show that the primary gas-liquid two-phase inclusions and a small amount of single-liquid inclusions are mainly developed in the quartz in the main mineralization stage. The results of microscopic temperature measurement show that the ore-forming fluid which has low temperature (151.7℃ -205.8 ℃), low salinity(2.06wt% - 4.94wt%NaCl), low density (0.86 -0.92 g/cm^( 3)) and shallow formation (1.5 -3.0 km) is a hydrothermal solution of NaCl-H_(2)O system. Hydrogen and oxygen isotope results show that the ore-forming fluids mainly come from atmospheric precipitation, with a small amount of magmatic fluids participating. It is preliminarily determined that the South Narimalahei copper polymetallic deposit is a low- temperature hydrothermal vein deposit.
