目的:探讨发生早产小于胎龄儿(small for gestational age infant,SGA)的高危因素。方法:回顾性分析2007年1月—2016年12月在汕头大学医学院第一附属医院住院的1 675例SGA的胎龄、性别、分型、母亲围产期情况、新生儿患病情况等临床资料...目的:探讨发生早产小于胎龄儿(small for gestational age infant,SGA)的高危因素。方法:回顾性分析2007年1月—2016年12月在汕头大学医学院第一附属医院住院的1 675例SGA的胎龄、性别、分型、母亲围产期情况、新生儿患病情况等临床资料,采用Logistic回归分析早产SGA的高危因素。结果:10年间SGA发生率13.1%(1 675/12 822),以足月儿(63.0%)、匀称型(66.0%)多见,无性别差异;胎儿附属物异常以胎膜早破(22.8%)、羊水异常(14.3%)、胎盘异常(11.6%)、脐带异常(10.4%)为常见;SGA患儿母亲最常见的围产期疾病分别是妊娠期高血压(16.5%)、阴道出血(3.9%)、贫血(3.2%)、糖尿病(2.7%)、绒毛膜羊膜炎(2.6%);SGA患儿最主要的疾病分别是高胆红素血症(67.9%)、感染性疾病(42.4%)、缺氧缺血性脑病(24.6%)、窒息(16.5%)、弥散性血管内凝血(4.7%)。流产次数多(OR=1.258,95%CI:1.058~1.497)、多胎(OR=3.739,95%CI:2.731~5.117)、胎盘异常(OR=2.908,95%CI:2.009~4.211)、胎膜早破(OR=2.597,95%CI:1.973~3.417)、母体妊娠期高血压疾病(OR=6.124,95%CI:4.326~8.670)、孕期阴道出血史(OR=2.213,95%CI:1.302~3.760)是早产SGA发生的高危因素。结论:SGA新生儿以足月儿、匀称型多见,妊娠期高血压疾病是SGA患儿母亲最常见的围产期疾病,SGA新生儿最常见疾病为高胆红素血症、感染、缺氧缺血性脑病。多次流产、多胎、胎盘异常、胎膜早破、妊娠期高血压疾病、孕期阴道出血等是发生早产SGA的高危因素。展开更多
Solid-state grinding is a simple and effective method to introduce guest species into the channels of microporous materials through filling.The structure and the surface acidity of the materials were obtained from BET...Solid-state grinding is a simple and effective method to introduce guest species into the channels of microporous materials through filling.The structure and the surface acidity of the materials were obtained from BET isotherms and NH3-TPD,respectively.XRD,UV-vis,UV diffuse-reflectance,and TEM were used to characterize the phases,and the morphology,respectively.The clustered layers of MgO-Al2O3phases were formed in the internal pore surface and were highly dispersed inside the channels of the ZSM-5 host.So the volume of MgO-Al2O3/ZSM-5 composite was larger than the ZSM-5 zeolite itself and some mesoporous channels appeared when Mg/Al species entered the channels.Meanwhile,new acid sites emerged in MgO-Al2O3/ZSM-5 composite and the acid amount of the sample changed.The improved Pt dispersion and the increased acid content would cause the increase of propane conversion and the modification of selectivity during the reaction.展开更多
文摘目的:探讨发生早产小于胎龄儿(small for gestational age infant,SGA)的高危因素。方法:回顾性分析2007年1月—2016年12月在汕头大学医学院第一附属医院住院的1 675例SGA的胎龄、性别、分型、母亲围产期情况、新生儿患病情况等临床资料,采用Logistic回归分析早产SGA的高危因素。结果:10年间SGA发生率13.1%(1 675/12 822),以足月儿(63.0%)、匀称型(66.0%)多见,无性别差异;胎儿附属物异常以胎膜早破(22.8%)、羊水异常(14.3%)、胎盘异常(11.6%)、脐带异常(10.4%)为常见;SGA患儿母亲最常见的围产期疾病分别是妊娠期高血压(16.5%)、阴道出血(3.9%)、贫血(3.2%)、糖尿病(2.7%)、绒毛膜羊膜炎(2.6%);SGA患儿最主要的疾病分别是高胆红素血症(67.9%)、感染性疾病(42.4%)、缺氧缺血性脑病(24.6%)、窒息(16.5%)、弥散性血管内凝血(4.7%)。流产次数多(OR=1.258,95%CI:1.058~1.497)、多胎(OR=3.739,95%CI:2.731~5.117)、胎盘异常(OR=2.908,95%CI:2.009~4.211)、胎膜早破(OR=2.597,95%CI:1.973~3.417)、母体妊娠期高血压疾病(OR=6.124,95%CI:4.326~8.670)、孕期阴道出血史(OR=2.213,95%CI:1.302~3.760)是早产SGA发生的高危因素。结论:SGA新生儿以足月儿、匀称型多见,妊娠期高血压疾病是SGA患儿母亲最常见的围产期疾病,SGA新生儿最常见疾病为高胆红素血症、感染、缺氧缺血性脑病。多次流产、多胎、胎盘异常、胎膜早破、妊娠期高血压疾病、孕期阴道出血等是发生早产SGA的高危因素。
基金the financial supports of the National Natural Science Foundation of China(Grant No.21376051,21106017,21306023 and 51077013)the Natural Science Foundation of Jiangsu(Grant No.BK20131288)+3 种基金the Fund Project for Transformation of Scientific and Technological Achievements of Jiangsu Province of China(Grant No.BA2011086)the Specialized Research Fund for the Doctoral Program of Higher Education of China(Grant No.20100092120047)the Key Program for the Scientific Research Guiding Fund of Basic Scientific Research Operation Expenditure of Southeast University(Grant No.3207043101)Instrumental Analysis Fund of Southeast University
文摘Solid-state grinding is a simple and effective method to introduce guest species into the channels of microporous materials through filling.The structure and the surface acidity of the materials were obtained from BET isotherms and NH3-TPD,respectively.XRD,UV-vis,UV diffuse-reflectance,and TEM were used to characterize the phases,and the morphology,respectively.The clustered layers of MgO-Al2O3phases were formed in the internal pore surface and were highly dispersed inside the channels of the ZSM-5 host.So the volume of MgO-Al2O3/ZSM-5 composite was larger than the ZSM-5 zeolite itself and some mesoporous channels appeared when Mg/Al species entered the channels.Meanwhile,new acid sites emerged in MgO-Al2O3/ZSM-5 composite and the acid amount of the sample changed.The improved Pt dispersion and the increased acid content would cause the increase of propane conversion and the modification of selectivity during the reaction.
