背景:冻存能够较好地保证血管结构的完整性,如何改善移植后排斥反应的问题受到越来越多的关注。目的:综述不同冷冻技术降低同种异体血管移植排斥反应的研究进展,以期为临床研究提供参考。方法:系统检索中英文数据库CNKI、万方和PubMed...背景:冻存能够较好地保证血管结构的完整性,如何改善移植后排斥反应的问题受到越来越多的关注。目的:综述不同冷冻技术降低同种异体血管移植排斥反应的研究进展,以期为临床研究提供参考。方法:系统检索中英文数据库CNKI、万方和PubMed以及在线网站Baidu和Google Scholar自建库以来发表的降低同种异体血管移植排斥反应的相关文献。中文检索关键词:心血管疾病、内皮细胞、低温冻存、血管移植、免疫原性、排斥反应,同种异体移植和冷冻保护剂;英文检索关键词:cardiovascular disease、endothelial cells、cryopreservation、blood vessel transplantation or vascular graft、Immunogenicity、immune rejection、allograft or allogeneic transplantation or allograft transplantation and cryoprotectant。按照纳入排除标准共选取68篇文献进行综述。结果与结论:①综述发现通过改进现有冷冻技术能够降低同种异体血管移植排斥反应,其中主要涉及冻融方式和冻存保护剂的选择。②现有研究提示冻干法优于低温冻存,但限于条件未能广泛开展,现仍以低温冻存为主,其中玻璃化冻存、缓慢复温和使用不锈钢乃至含银材料效果优于程序式冻存及快速复温。③渗透性和非渗透性冻存保护剂的联合选择,可以在降低其毒性的同时,进一步减少排斥反应的发生。展开更多
The humic acids (HAs) isolated from the sediments of the various rivers,lakes,and reservoirs in China were studied using elemental analyzer,fourier transform infrared (FT-IR),and CP/MAS 13C nuclear magnetic resonance ...The humic acids (HAs) isolated from the sediments of the various rivers,lakes,and reservoirs in China were studied using elemental analyzer,fourier transform infrared (FT-IR),and CP/MAS 13C nuclear magnetic resonance (NMR) spectroscopy.The results showed that the HAs were characterized by some common chemical and physicochemical properties,but they also pose some differences in the C-containing functional groups.The C/N,C/H,O/C,and O/H ratios differ widely for the various HAs,showing that the elemental comp...展开更多
Dioxin-like polychlorinated biphenyls(PCBs) are a class of toxic and persistent chemicals that are often found in the environment.The determination of dioxin-like PCBs in Fildes Peninsula,Antarctica,is reported in thi...Dioxin-like polychlorinated biphenyls(PCBs) are a class of toxic and persistent chemicals that are often found in the environment.The determination of dioxin-like PCBs in Fildes Peninsula,Antarctica,is reported in this paper.Dioxin-like PCBs were widely distributed in Antarctic soil and moss with concentration of 2.23-27.2 pg/g in soil and 10.4-812 pg/g in moss.The highest concentrations were found in the Ardley Island area and the lowest concentrations on the west coast.The contribution of PCB-118 to the ∑12PCBs ranged from 36.0% to 69.6% in soil,and 17.2% to 43.4% in moss.The congener specific patterns in soil and moss were similar.Long-range atmospheric transport is thought to be the main source of PCBs detected on King George Island.The ∑12PCBs toxic equivalent(TEQ) in soil was 0.400×10?3 to 516×10?3 pg(TEQ)/g with a mean value of 147×10?3 pg(TEQ)/g.PCB-126 had the largest contribution(81.1%) to the ∑12PCBs TEQ in soil.The ∑12PCBs TEQ in moss ranged from 2.90×10?3 to 1.19 pg/g with a mean value of 0.482 pg/g.PCB-126 was also the largest contributor(91.4%) to the ∑12PCBs TEQ in moss.The mean TEQ in moss was about 40 times that in soil.展开更多
文摘背景:冻存能够较好地保证血管结构的完整性,如何改善移植后排斥反应的问题受到越来越多的关注。目的:综述不同冷冻技术降低同种异体血管移植排斥反应的研究进展,以期为临床研究提供参考。方法:系统检索中英文数据库CNKI、万方和PubMed以及在线网站Baidu和Google Scholar自建库以来发表的降低同种异体血管移植排斥反应的相关文献。中文检索关键词:心血管疾病、内皮细胞、低温冻存、血管移植、免疫原性、排斥反应,同种异体移植和冷冻保护剂;英文检索关键词:cardiovascular disease、endothelial cells、cryopreservation、blood vessel transplantation or vascular graft、Immunogenicity、immune rejection、allograft or allogeneic transplantation or allograft transplantation and cryoprotectant。按照纳入排除标准共选取68篇文献进行综述。结果与结论:①综述发现通过改进现有冷冻技术能够降低同种异体血管移植排斥反应,其中主要涉及冻融方式和冻存保护剂的选择。②现有研究提示冻干法优于低温冻存,但限于条件未能广泛开展,现仍以低温冻存为主,其中玻璃化冻存、缓慢复温和使用不锈钢乃至含银材料效果优于程序式冻存及快速复温。③渗透性和非渗透性冻存保护剂的联合选择,可以在降低其毒性的同时,进一步减少排斥反应的发生。
基金the National Basic Research Program (973) of China (No.2004CB418502,2003CB415002)the National Natural Science Foundation of China (No.29977002).
文摘The humic acids (HAs) isolated from the sediments of the various rivers,lakes,and reservoirs in China were studied using elemental analyzer,fourier transform infrared (FT-IR),and CP/MAS 13C nuclear magnetic resonance (NMR) spectroscopy.The results showed that the HAs were characterized by some common chemical and physicochemical properties,but they also pose some differences in the C-containing functional groups.The C/N,C/H,O/C,and O/H ratios differ widely for the various HAs,showing that the elemental comp...
基金supported by the Postdoctoral Science Foundation of China (201004800123)the China Polar Science Strategic Fund (20070214)the Foundation of State Key Joint Laboratory for Environmental Simulation & Pollution Control
文摘Dioxin-like polychlorinated biphenyls(PCBs) are a class of toxic and persistent chemicals that are often found in the environment.The determination of dioxin-like PCBs in Fildes Peninsula,Antarctica,is reported in this paper.Dioxin-like PCBs were widely distributed in Antarctic soil and moss with concentration of 2.23-27.2 pg/g in soil and 10.4-812 pg/g in moss.The highest concentrations were found in the Ardley Island area and the lowest concentrations on the west coast.The contribution of PCB-118 to the ∑12PCBs ranged from 36.0% to 69.6% in soil,and 17.2% to 43.4% in moss.The congener specific patterns in soil and moss were similar.Long-range atmospheric transport is thought to be the main source of PCBs detected on King George Island.The ∑12PCBs toxic equivalent(TEQ) in soil was 0.400×10?3 to 516×10?3 pg(TEQ)/g with a mean value of 147×10?3 pg(TEQ)/g.PCB-126 had the largest contribution(81.1%) to the ∑12PCBs TEQ in soil.The ∑12PCBs TEQ in moss ranged from 2.90×10?3 to 1.19 pg/g with a mean value of 0.482 pg/g.PCB-126 was also the largest contributor(91.4%) to the ∑12PCBs TEQ in moss.The mean TEQ in moss was about 40 times that in soil.
