目的探讨低钠透析联合高通量透析对尿毒症维持性血液透析并发顽固性高血压患者血压、心功能的影响。方法选取尿毒症维持性血液透析并发顽固性高血压患者72例,按照随机数字表法分为三组,每组24例,A组给予低钠联合高通量透析,B组给予高通...目的探讨低钠透析联合高通量透析对尿毒症维持性血液透析并发顽固性高血压患者血压、心功能的影响。方法选取尿毒症维持性血液透析并发顽固性高血压患者72例,按照随机数字表法分为三组,每组24例,A组给予低钠联合高通量透析,B组给予高通量透析,C组常规透析;比较三组总有效率和不良反应发生率;采用动态血压监测仪监测患者血压节律;用彩色多普勒超声仪检测心功能参数;采用化学发光法检测甲状旁腺激素(PTH);采用化学发光免疫法检测血肌酐(Scr)和尿素氮(BUN)。结果A组总有效率高于B组和C组(P均<0.05),B组总有效率高于C组(P<0.05)。A组治疗后24 h SBP、24 h DBP、dSBP、dDBP、nSBP和nDBP低于B组和C组(P均<0.05),B组治疗后24 h SBP、24 h DBP、dSBP、dDBP、nSBP和nDBP低于C组(P均<0.05)。A组治疗后CI、CO、SV、E/A、EI/AI低于B组和C组(P均<0.05),B组治疗后CI、CO、SV、E/A、EI/AI低于C组(P均<0.05)。A组治疗后PTH、Scr和BUN低于B组和C组(P均<0.05),B组治疗后PTH、Scr和BUN低于C组(P均<0.05)。A组治疗后不良反应发生率低于B组和C组(P均<0.05),B组治疗后不良反应发生率低于C组(P<0.05)。结论低钠透析联合高通量透析可促进尿毒症维持性血液透析并发顽固性高血压患者血压恢复,改善心功能。展开更多
Atmospheric-pressure argon plasmas have received increasing attention due to their high potential in many industrial and biomedical applications. In this paper, a 1-D fluid model is used for studying the particle dens...Atmospheric-pressure argon plasmas have received increasing attention due to their high potential in many industrial and biomedical applications. In this paper, a 1-D fluid model is used for studying the particle density characteristics of the argon plasmas generated by the pulsed dielectric barrier discharges. The temporal evolutions of the axial particle density distributions are illustrated, and the influences of changing the main discharge conditions on the averaged particle densities are researched by independently varying the various discharge conditions. The calculation results show that the electron density and the ion density reach two peaks near the momentary cathodes during the rising and the falling edges of the pulsed voltage. Compared with the charged particle densities, the densities of the resonance state atom Arr and the metastable state atom Arm have more uniform axial distributions, reach higher maximums and decay more slowly. During the platform of the pulsed voltage and the time interval between the pulses, the densities of the excited state atom Ar* are far lower than those of the Arr or the Arm. The averaged particle densities of the different considered particles increase with the increases of the amplitude and the frequency of the pulsed voltage. Narrowing the discharge gap and increasing the relative dielectric constant of the dielectric also contribute to the increase of the averaged particle densities. The effects of reducing the discharge gap distance on the neutral particle densities are more significant than the influences on the charged particle densities.展开更多
文摘目的探讨低钠透析联合高通量透析对尿毒症维持性血液透析并发顽固性高血压患者血压、心功能的影响。方法选取尿毒症维持性血液透析并发顽固性高血压患者72例,按照随机数字表法分为三组,每组24例,A组给予低钠联合高通量透析,B组给予高通量透析,C组常规透析;比较三组总有效率和不良反应发生率;采用动态血压监测仪监测患者血压节律;用彩色多普勒超声仪检测心功能参数;采用化学发光法检测甲状旁腺激素(PTH);采用化学发光免疫法检测血肌酐(Scr)和尿素氮(BUN)。结果A组总有效率高于B组和C组(P均<0.05),B组总有效率高于C组(P<0.05)。A组治疗后24 h SBP、24 h DBP、dSBP、dDBP、nSBP和nDBP低于B组和C组(P均<0.05),B组治疗后24 h SBP、24 h DBP、dSBP、dDBP、nSBP和nDBP低于C组(P均<0.05)。A组治疗后CI、CO、SV、E/A、EI/AI低于B组和C组(P均<0.05),B组治疗后CI、CO、SV、E/A、EI/AI低于C组(P均<0.05)。A组治疗后PTH、Scr和BUN低于B组和C组(P均<0.05),B组治疗后PTH、Scr和BUN低于C组(P均<0.05)。A组治疗后不良反应发生率低于B组和C组(P均<0.05),B组治疗后不良反应发生率低于C组(P<0.05)。结论低钠透析联合高通量透析可促进尿毒症维持性血液透析并发顽固性高血压患者血压恢复,改善心功能。
基金supported by Natural Science Foundation of Shandong Province,China(No.ZR2015AQ008)Project of Shandong Province Higher Educational Science and Technology Program of China(No.J15LJ04)
文摘Atmospheric-pressure argon plasmas have received increasing attention due to their high potential in many industrial and biomedical applications. In this paper, a 1-D fluid model is used for studying the particle density characteristics of the argon plasmas generated by the pulsed dielectric barrier discharges. The temporal evolutions of the axial particle density distributions are illustrated, and the influences of changing the main discharge conditions on the averaged particle densities are researched by independently varying the various discharge conditions. The calculation results show that the electron density and the ion density reach two peaks near the momentary cathodes during the rising and the falling edges of the pulsed voltage. Compared with the charged particle densities, the densities of the resonance state atom Arr and the metastable state atom Arm have more uniform axial distributions, reach higher maximums and decay more slowly. During the platform of the pulsed voltage and the time interval between the pulses, the densities of the excited state atom Ar* are far lower than those of the Arr or the Arm. The averaged particle densities of the different considered particles increase with the increases of the amplitude and the frequency of the pulsed voltage. Narrowing the discharge gap and increasing the relative dielectric constant of the dielectric also contribute to the increase of the averaged particle densities. The effects of reducing the discharge gap distance on the neutral particle densities are more significant than the influences on the charged particle densities.