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补肾疏肝法对迟发性性腺功能减退症患者胰岛素样生长因子-1、胰岛素样因子3影响的研究
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作者 王益俊 陈凤兰 +4 位作者 李轩 廖敦 苏玲君 徐敏嫦 李嘉乐 《现代中西医结合杂志》 CAS 2023年第10期1330-1333,1340,共5页
目的观察补肾疏肝中药对男性迟发性性腺功能减退症(LOH)患者血清胰岛素样生长因子-1(IGF-1)、胰岛素样因子3(INSL3)的影响,探索补肾疏肝法治疗LOH的可能机制。方法选择2019年3月-2022年3月南方医科大学附属第十医院治疗的90例LOH肾虚肝... 目的观察补肾疏肝中药对男性迟发性性腺功能减退症(LOH)患者血清胰岛素样生长因子-1(IGF-1)、胰岛素样因子3(INSL3)的影响,探索补肾疏肝法治疗LOH的可能机制。方法选择2019年3月-2022年3月南方医科大学附属第十医院治疗的90例LOH肾虚肝郁证患者,根据就诊先后按随机数字表法将患者分为试验组和对照组,每组45例。试验组以补肾疏肝法治疗,药用还少丹合逍遥丸改煎剂加减内服,每日1剂;对照组给予十一酸睾酮胶囊口服,80 mg/次,2次/d,4周后用量减至40 mg/次,2次/d。2组均用药12周。观察比较2组患者治疗前后中老年男子部分雄激素缺乏综合征(PADAM)评分及血清睾酮(T)、促卵泡生成素(FSH)、黄体生成素(LH)、IGF-1及INSL3水平。结果与治疗前比较,2组患者治疗后PADAM评分均明显降低(P均<0.05),且试验组明显低于对照组(P<0.05);治疗后试验组患者血清T、血清IGF-1水平均明显升高(P均<0.05),FSH、LH水平均明显降低(P均<0.05),且试验组血清T水平明显低于对照组(P<0.05),IGF-1水平明显高于对照组(P<0.05);治疗后对照组患者血清T水平明显升高(P<0.05),IGF-1、FSH、LH水平均无明显变化(P均>0.05);2组INSL3水平均无明显变化(P均<0.05)。结论补肾疏肝法可能通过提升血清IGF-1、促进T合成及分泌,延缓INSL3下降,保护睾丸功能,有效治疗LOH。 展开更多
关键词 补肾疏肝法 迟发性性腺功能减退症 睾酮 胰岛素样生长因子-1 胰岛素样因子3
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Rural Revitalization Construction and Local Landscape Design:A Case Study of Qili Village,Aijia Town,Dianjun District,Yichang
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作者 MAO Mao su lingjun 《Journal of Landscape Research》 2022年第2期33-38,共6页
In the context of the 2021 No.1 central document released and the year when the rural revitalization was first launched, Qili Village of Aijia Town with rich natural landscape resources, convenient location and transp... In the context of the 2021 No.1 central document released and the year when the rural revitalization was first launched, Qili Village of Aijia Town with rich natural landscape resources, convenient location and transportation is taken as an example. Combining ecological design concept and local landscape design idea of landscape architecture specialty, and taking “one core, two main lines, five nodes,and comprehensive experience” as master plan, it tries to build regional local landscape of “one village, one product” and condense the “nostalgia” artistic conception of Qili Village as the core, protect and repair the livable ecological environment, improve infrastructure construction, create high-quality leisure agricultural tourism projects, and attract talents to return home and start businesses. It will fully realize the “five revitalization” of Qili Village, thereby providing theoretical and practical reference for rural revitalization in Yichang and its surrounding areas. 展开更多
关键词 Rural vitalization Leisure agricultural tourism Ecological environment Nostalgic artistic conception
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