目的:探讨外周血淋巴细胞与单核细胞比值(lymphocyte to monocyte ratio,LMR)在原发胃肠道弥漫性大B细胞淋巴瘤(primary gastrointestinal diffuse large B cell lymphoma,PGI-DLBCL)疾病进展中的意义。方法:收集本院2011年1月至2015年1...目的:探讨外周血淋巴细胞与单核细胞比值(lymphocyte to monocyte ratio,LMR)在原发胃肠道弥漫性大B细胞淋巴瘤(primary gastrointestinal diffuse large B cell lymphoma,PGI-DLBCL)疾病进展中的意义。方法:收集本院2011年1月至2015年12月期间经病理学确诊为PGI-DLBCL的43例患者的临床资料,并随访观察患者疾病进展情况,分析LMR与患者2年PFS(%)之间的关系。结果:根据ROC曲线PGI-DLBCL患者LMR最具差异性的界限值为2.6。单因素分析显示,LMR(P<0.05)、大包块病变(P<0.01)和IPI(P<0.05)为影响患者2年PFS(%)的预后因素。COX回归模型多因素分析显示,LMR<2.6[(危险比(RR)=3.083,95%CI1.828-8.313,P<0.01)]、大包块病变(RR=2.718,95%CI1.339-6.424,P<0.05)为2年PFS(%)的不良预后相关因素。结论:LMR<2.6,大包块病变与PGI-DLBCL患者疾病的进展相关。展开更多
Several new stripe rust pathogen races emerged in the wheat growing regions of China in recent years.These races were virulent to most of the designated wheat seedling resistance genes.Thus,it is necessary and worthwh...Several new stripe rust pathogen races emerged in the wheat growing regions of China in recent years.These races were virulent to most of the designated wheat seedling resistance genes.Thus,it is necessary and worthwhile to identify new valuable resistant materials for the sake of diversifying resistant sources,pyramiding different resistance genes and achieving durable resistance.Here,we identified the resistance gene,temporarily designated as YrH9017,in wheat-Psathyrostachys huashanica introgression line H9017-14-16-5-3.A total of 146 F2 plants and their derived F2:3 families in a cross of Mingxian 169 and H9017-14-16-5-3 were used to evaluate seedling stripe rust response and as a mapping population.Finally,we constructed a genetic map including eight simple sequence repeat(SSR) markers and expressed sequence tag(EST) markers.YrH9017 was located on the long arm of chromosome 2A and closely linked with two EST-sequence tagged site(EST-STS) markers BG604577 and BE471201 at 1.3 and 1.8 cM distance,respectively.The two closest markers could be used for marker-assisted selection of YrH9017 in breeding.展开更多
Based on the method of discrete phase, the law of droplets’ deposition in the last stage stationary blade of a supercritical 600 MW Steam Turbine is simulated in the first place of this paper by using the Wet-steam m...Based on the method of discrete phase, the law of droplets’ deposition in the last stage stationary blade of a supercritical 600 MW Steam Turbine is simulated in the first place of this paper by using the Wet-steam model in commercial software FLUENT, where the influence of inlet angle of water droplets of the stationary blades is also considered. Through the calculation, the relationship between the deposition and the diameter of water droplets is revealed. Then, the amount of droplets deposition in the suction and pressure surface is derived. The result is compared with experimental data and it proves that the numerical simulation result obtained in this paper is reasonable. Finally, a formula of the relationship between the diameter of water droplets and the inlet angle is fit, which could be used for approximate calculation in the engineering applications.展开更多
[ Objective] The paper was to understand the resistance of Fusarium graminearum to carbendazim and prochloraz in the main wheat producing areas in Hubei Province. [ Method] Totally 350 F. graminearum strains isolated ...[ Objective] The paper was to understand the resistance of Fusarium graminearum to carbendazim and prochloraz in the main wheat producing areas in Hubei Province. [ Method] Totally 350 F. graminearum strains isolated in 2014 were determined to clear their sensitivity to carbendazim and prochloraz. [ Result] ALl isolates were sensitive to carbendazim and procidoraz in Hubei Province, and carbendazim was still valuable in controlling Fusarium head blight. The control effect of prochloraz was better than that of carbendazim, and the combination of prochloraz and carbendazim at the proportion of 1：7 received the best control effect. [ Conclusion ] Combination of chemical agents will occupy a more and more important position in future prevention and control against Fusarium head blight.展开更多
文摘目的:探讨外周血淋巴细胞与单核细胞比值(lymphocyte to monocyte ratio,LMR)在原发胃肠道弥漫性大B细胞淋巴瘤(primary gastrointestinal diffuse large B cell lymphoma,PGI-DLBCL)疾病进展中的意义。方法:收集本院2011年1月至2015年12月期间经病理学确诊为PGI-DLBCL的43例患者的临床资料,并随访观察患者疾病进展情况,分析LMR与患者2年PFS(%)之间的关系。结果:根据ROC曲线PGI-DLBCL患者LMR最具差异性的界限值为2.6。单因素分析显示,LMR(P<0.05)、大包块病变(P<0.01)和IPI(P<0.05)为影响患者2年PFS(%)的预后因素。COX回归模型多因素分析显示,LMR<2.6[(危险比(RR)=3.083,95%CI1.828-8.313,P<0.01)]、大包块病变(RR=2.718,95%CI1.339-6.424,P<0.05)为2年PFS(%)的不良预后相关因素。结论:LMR<2.6,大包块病变与PGI-DLBCL患者疾病的进展相关。
基金funded by the National Natural Science Foundation of China (31660513,31501620 and 31701911)the Provincial Natural Science Foundation of Qinghai,China (2017-ZJ-793)
文摘Several new stripe rust pathogen races emerged in the wheat growing regions of China in recent years.These races were virulent to most of the designated wheat seedling resistance genes.Thus,it is necessary and worthwhile to identify new valuable resistant materials for the sake of diversifying resistant sources,pyramiding different resistance genes and achieving durable resistance.Here,we identified the resistance gene,temporarily designated as YrH9017,in wheat-Psathyrostachys huashanica introgression line H9017-14-16-5-3.A total of 146 F2 plants and their derived F2:3 families in a cross of Mingxian 169 and H9017-14-16-5-3 were used to evaluate seedling stripe rust response and as a mapping population.Finally,we constructed a genetic map including eight simple sequence repeat(SSR) markers and expressed sequence tag(EST) markers.YrH9017 was located on the long arm of chromosome 2A and closely linked with two EST-sequence tagged site(EST-STS) markers BG604577 and BE471201 at 1.3 and 1.8 cM distance,respectively.The two closest markers could be used for marker-assisted selection of YrH9017 in breeding.
文摘Based on the method of discrete phase, the law of droplets’ deposition in the last stage stationary blade of a supercritical 600 MW Steam Turbine is simulated in the first place of this paper by using the Wet-steam model in commercial software FLUENT, where the influence of inlet angle of water droplets of the stationary blades is also considered. Through the calculation, the relationship between the deposition and the diameter of water droplets is revealed. Then, the amount of droplets deposition in the suction and pressure surface is derived. The result is compared with experimental data and it proves that the numerical simulation result obtained in this paper is reasonable. Finally, a formula of the relationship between the diameter of water droplets and the inlet angle is fit, which could be used for approximate calculation in the engineering applications.
基金Supported by Key Technologies R&D Program of Hubei(2015BBA152)Innovative Experiment Project of College Students(20150086)Natural Science Foundation of Hubei Province(2014CFB367)
文摘[ Objective] The paper was to understand the resistance of Fusarium graminearum to carbendazim and prochloraz in the main wheat producing areas in Hubei Province. [ Method] Totally 350 F. graminearum strains isolated in 2014 were determined to clear their sensitivity to carbendazim and prochloraz. [ Result] ALl isolates were sensitive to carbendazim and procidoraz in Hubei Province, and carbendazim was still valuable in controlling Fusarium head blight. The control effect of prochloraz was better than that of carbendazim, and the combination of prochloraz and carbendazim at the proportion of 1：7 received the best control effect. [ Conclusion ] Combination of chemical agents will occupy a more and more important position in future prevention and control against Fusarium head blight.
