The interactions between konjac glucomannan（KGM） and soy protein isolate （SPI） were studied with the method of molecular dynamics simulation. Part representative structures segments of KGM and SPI were used as mod...The interactions between konjac glucomannan（KGM） and soy protein isolate （SPI） were studied with the method of molecular dynamics simulation. Part representative structures segments of KGM and SPI were used as mode, and the force-field was FF03. The stability and sites of KGM/SPI interactions in water were researched at 363 K with the following results： the potential energy （EPOT） of the mixed gel dropped, while that of single KGM gel increased. The surface area （SA） of KGM in the mixed system was decreased to 401.41 from 1 267.54 Az, and that of SPI to 484.94 from 1 943.28 A2. The sum potential energy of KGM and soy protein in the mixed system was decreased to -13 402.41 from -5 768.56 kcal mol^-1. The variations of two parameters showed that the stability of compound gel KGM/SPI was improved, which was consistent with the previous studies. The sites of interactions in the mixed gel were the -OH groups on C（2） in KGM mannose and glucose, and the amide linkage group on Histidine, Asparagine and Leucine in SPI. The hydrogen bond was formed directly or indirectly by the bridge of waters.展开更多
The effect of boron on the properties of Konjac Glucomanan （KGM） has been investigated by the method of experiment and molecular dynamic simulation. Upon analysis, the property and structure of KGM are apt to be aff...The effect of boron on the properties of Konjac Glucomanan （KGM） has been investigated by the method of experiment and molecular dynamic simulation. Upon analysis, the property and structure of KGM are apt to be affected by boron and structural reasons for property change were discussed. In detail, the addition low concentration borax can increase the systematic inherent viscosity, by contrast, high concentration borax has opposite effect on the viscosity. When adding borax, the micropores on KGM film surface decrease or disappear, leading to more compact and uniform on the film surface. The structure of KGM-Boron complex is described as the coordination reaction between KGM and boron. The main reaction points are hydroxyl group on C（6） position of sugar as well as those on C（2） and C（3） positions of mannose with two kinds of complexes formation： B-K2 and KB-K. And KB-K mainly consists of g-b-m.展开更多
目的分析对比国内外电子健康素养相关研究热点,为提高我国不同人群电子健康素养的研究提供参考。方法选取1999年1月~2021年12月发表于中国知网(CNKI)和Web of Science核心合集数据库中的共698篇文献行Citespace可视化分析。结果国外发...目的分析对比国内外电子健康素养相关研究热点,为提高我国不同人群电子健康素养的研究提供参考。方法选取1999年1月~2021年12月发表于中国知网(CNKI)和Web of Science核心合集数据库中的共698篇文献行Citespace可视化分析。结果国外发文量总体为上升趋势,热点为电子健康素养理论研究、影响因素、获取渠道、获取能力,还包括电子健康评估与应用,慢性疾病健康干预,公共卫生保健等。我国发文量仍处于起步阶段,呈缓慢上升趋势,国内研究机构缺乏合作,研究热点为电子健康素养理论模型,影响因素,测量与应用,健康干预等方面。结论国内外电子健康素养相关研究均处于初始阶段,未来还需要更多的探索和发展。展开更多
基金supported by the National Natural Science Foundation of China(30871749,30901004)
文摘The interactions between konjac glucomannan（KGM） and soy protein isolate （SPI） were studied with the method of molecular dynamics simulation. Part representative structures segments of KGM and SPI were used as mode, and the force-field was FF03. The stability and sites of KGM/SPI interactions in water were researched at 363 K with the following results： the potential energy （EPOT） of the mixed gel dropped, while that of single KGM gel increased. The surface area （SA） of KGM in the mixed system was decreased to 401.41 from 1 267.54 Az, and that of SPI to 484.94 from 1 943.28 A2. The sum potential energy of KGM and soy protein in the mixed system was decreased to -13 402.41 from -5 768.56 kcal mol^-1. The variations of two parameters showed that the stability of compound gel KGM/SPI was improved, which was consistent with the previous studies. The sites of interactions in the mixed gel were the -OH groups on C（2） in KGM mannose and glucose, and the amide linkage group on Histidine, Asparagine and Leucine in SPI. The hydrogen bond was formed directly or indirectly by the bridge of waters.
基金This work was supported by the National Natural Foundation (30371009), Foundation of Education Committee of Fujian Province(JA03059) and Key Science & Technology Item of Fujian Province (2003Y008).
文摘The effect of boron on the properties of Konjac Glucomanan （KGM） has been investigated by the method of experiment and molecular dynamic simulation. Upon analysis, the property and structure of KGM are apt to be affected by boron and structural reasons for property change were discussed. In detail, the addition low concentration borax can increase the systematic inherent viscosity, by contrast, high concentration borax has opposite effect on the viscosity. When adding borax, the micropores on KGM film surface decrease or disappear, leading to more compact and uniform on the film surface. The structure of KGM-Boron complex is described as the coordination reaction between KGM and boron. The main reaction points are hydroxyl group on C（6） position of sugar as well as those on C（2） and C（3） positions of mannose with two kinds of complexes formation： B-K2 and KB-K. And KB-K mainly consists of g-b-m.
文摘目的分析对比国内外电子健康素养相关研究热点,为提高我国不同人群电子健康素养的研究提供参考。方法选取1999年1月~2021年12月发表于中国知网(CNKI)和Web of Science核心合集数据库中的共698篇文献行Citespace可视化分析。结果国外发文量总体为上升趋势,热点为电子健康素养理论研究、影响因素、获取渠道、获取能力,还包括电子健康评估与应用,慢性疾病健康干预,公共卫生保健等。我国发文量仍处于起步阶段,呈缓慢上升趋势,国内研究机构缺乏合作,研究热点为电子健康素养理论模型,影响因素,测量与应用,健康干预等方面。结论国内外电子健康素养相关研究均处于初始阶段,未来还需要更多的探索和发展。
