通过问卷调查研究了住宅环境中病态建筑综合征（sick Building syndrome，SBS）患病率和相关的危险因素．在2010年12月到2011年4月期间，课题组通过对重庆市的幼儿园进行随机抽样，一共有5299名3-6岁儿童的父亲或母亲回答并返回了调查...通过问卷调查研究了住宅环境中病态建筑综合征（sick Building syndrome，SBS）患病率和相关的危险因素．在2010年12月到2011年4月期间，课题组通过对重庆市的幼儿园进行随机抽样，一共有5299名3-6岁儿童的父亲或母亲回答并返回了调查问卷．儿童家长的SBS患病率（每周出现SBS的百分比）如下：一般性症状为11．4％；黏膜性症状为7．1％；皮肤性症状为4．4％．应用多元逻辑回归（通过控制家长的性别和哮喘／过敏性鼻炎／湿疹的影响）方法的分析结果表明：住宅靠近交通干线或高速公路是一般性症状、黏膜性症状和皮肤性症状的强烈危险因素（调整比值比aOR分别为：aOR=2．16，P〈0．001；aOR=2．69，P〈0．001；aOR=1．63，P〈0．01）；装修是一般性症状、黏膜性症状和皮肤性症状的危险因素（aOR分别为：aOR=2．00，P〈0．001：aOR=1．66，P〈0．01：aOR=1．66，P〈0．05）；新家具是一般性症状和皮肤性症状的危险因素（aOR分别为：aOR=2．16，P〈0．001；aOR=1．67，P〈0．01）．潮湿问题（霉点、湿点、水损和窗户凝水）、报告出现蟑螂、老鼠、蚊子／苍蝇及使用熏香均是SBS的危险因素．保护性因素包括每天清洁儿童的卧室和经常晾晒被褥．本研究表明成年人的病态建筑综合征与住宅环境相关．展开更多
Asthma,rhinitis and eczema(allergic or non-allergic)have increased throughout the world during the last decades,especially among children.Changes in the indoor environment are suspected to be important causes.China ha...Asthma,rhinitis and eczema(allergic or non-allergic)have increased throughout the world during the last decades,especially among children.Changes in the indoor environment are suspected to be important causes.China has experienced a dramatic change in indoor environmental exposures during the past two decades.However,such changes and their associations with children’s asthma and other health aspects have not been thoroughly studied.China,Children,Homes,Health(CCHH),Phase I,was a cross-sectional questionnaire survey of 48219 children 1–8 years old in 10 Chinese cities during 2010–2012.The questionnaire includes the International Study of Asthma and Allergies in Childhood(ISAAC)core health questions and additional questions regarding housing,life habits and outdoor environment.In health analyses,children aged 3–6 years old were included.The prevalences of doctor diagnosed asthma varied from 1.7%to 9.8%(mean 6.8%),a large increase from 0.91%in 1999 and 1.50%in2000.The prevalence of wheeze,rhinitis and atopic eczema(last 12 months)varied from 13.9%to 23.7%,24.0%to 50.8%and4.8%to 15.8%,respectively.Taiyuan had the lowest prevalences of all illnesses and Shanghai the highest,except for wheezewhere the highest value was for Urumqi.We found(1)no obvious association between disease prevalences and ambient PM10concentrations and(2)higher prevalences of disease in humid climates with hot summers and cold winters,but with no centrally heated buildings.Associations between the diseases and economic status as indexed by Gross Domestic Product(GDP)requires further study.展开更多
Prenatal and early life home environment might be related to children’s asthma or allergic diseases later in life.A cross-sectional epidemiological study was designed and a questionnaire survey was performed in 3700 ...Prenatal and early life home environment might be related to children’s asthma or allergic diseases later in life.A cross-sectional epidemiological study was designed and a questionnaire survey was performed in 3700 preschool children in urban areas in Taiyuan,Shanxi Province,China.Questions on children’s asthma and allergic diseases from the International Study on Asthma and Allergies in Childhood(ISAAC)were integrated with questions on home environment from the Swedish Dampness in Buildings and Health(DBH)study,appropriately modified for Chinese life habits.By multivariate regression analyses controlling for age,gender,heredity,location in urban/suburban or rural areas,environmental tobacco smoke(ETS)and breastfeeding,we found that home new furniture(HNF)before birth(referring to 1 year before pregnancy and during pregnancy)was positively associated with wheezing ever(odds ratio(OR)1.23 with 95%CI of 1.03–1.48)and wheezing last 12 months(1.24,1.00–1.54),allergic rhinitis(AR)(1.26,1.06–1.51),and eczema(1.42,1.01–1.99).HNF between 0–1 years old was also positively associated with wheezing last 12 months.Home new decoration(HND)during 0–1 years old was positively associated with AR symptoms and eczema symptoms,more in the last 12 months.Stronger positive associations were found for signs of home mold and dampness with almost all children’s asthmatic and allergic symptoms(OR ranging from 1.23–1.85,P<0.05).By mutual adjustment between HNF before children’s birth and home mold or dampness,all the significance remained unchanged.Prenatal HNF and home mold or dampness was independently associated with children’s asthmatic and allergic diseases later in life.展开更多
In order to evaluate the prevalence of childhood asthma,allergic diseases and pneumonia in Urumqi City,China,as well as its associations with housing and home characteristics,a cross-sectional study was performed in 4...In order to evaluate the prevalence of childhood asthma,allergic diseases and pneumonia in Urumqi City,China,as well as its associations with housing and home characteristics,a cross-sectional study was performed in 4618 children(81.7%response rate,average age 4.7±0.9 year,boys accounting for 53.7%).Questions on children’s asthma and allergic diseases were from the International Study on Asthma and Allergies in Childhood(ISAAC)and were integrated with questions on the home environment from the Dampness in Buildings and Health(DBH)study,slightly modified to account for Chinese building characteristics and life habits.The prevalences of physician diagnosed asthma,allergic rhinitis(AR)and pneumonia were 3.6%,8.7%and 40.9%,respectively.One fourth of children reported wheezing and more than 40%AR symptoms in the last 12 months.Controlling for confounding factors,positive associations were found for home mold/dampness and wheezing(adjusted odds ratio,aOR 1.33,95%CI 1.07 1.66),AR symptoms(1.34,1.09 1.64)last 12 months and physician diagnosed pneumonia(1.33,1.09 1.62).Floor material by wood,PVC or carpeting;and walls by wallpaper,painting or wood material,were positively associated with AR symptoms.Home environmental tobacco smoke(ETS)was positively associated with wheezing(1.23,1.04 1.46)and pneumonia(1.25,1.07 1.45).In conclusion,there was a relatively high prevalence of asthmatic and AR symptoms and diagnosed pneumonia in preschool children in Urumqi.Home signs of mold growth or dampness,windowpane condensation,as well as ETS and interior surface materials emitting chemicals were risk factors for allergic symptoms and pneumonia.展开更多
文摘通过问卷调查研究了住宅环境中病态建筑综合征（sick Building syndrome，SBS）患病率和相关的危险因素．在2010年12月到2011年4月期间，课题组通过对重庆市的幼儿园进行随机抽样，一共有5299名3-6岁儿童的父亲或母亲回答并返回了调查问卷．儿童家长的SBS患病率（每周出现SBS的百分比）如下：一般性症状为11．4％；黏膜性症状为7．1％；皮肤性症状为4．4％．应用多元逻辑回归（通过控制家长的性别和哮喘／过敏性鼻炎／湿疹的影响）方法的分析结果表明：住宅靠近交通干线或高速公路是一般性症状、黏膜性症状和皮肤性症状的强烈危险因素（调整比值比aOR分别为：aOR=2．16，P〈0．001；aOR=2．69，P〈0．001；aOR=1．63，P〈0．01）；装修是一般性症状、黏膜性症状和皮肤性症状的危险因素（aOR分别为：aOR=2．00，P〈0．001：aOR=1．66，P〈0．01：aOR=1．66，P〈0．05）；新家具是一般性症状和皮肤性症状的危险因素（aOR分别为：aOR=2．16，P〈0．001；aOR=1．67，P〈0．01）．潮湿问题（霉点、湿点、水损和窗户凝水）、报告出现蟑螂、老鼠、蚊子／苍蝇及使用熏香均是SBS的危险因素．保护性因素包括每天清洁儿童的卧室和经常晾晒被褥．本研究表明成年人的病态建筑综合征与住宅环境相关．
基金supported by the National Natural Science Foundation of China(51136002,51076079,51006057)Ministry of Science and Technology of China(2012BAJ02B03)National High Technology Research and Development Program of China(2010AA064903)
文摘Asthma,rhinitis and eczema(allergic or non-allergic)have increased throughout the world during the last decades,especially among children.Changes in the indoor environment are suspected to be important causes.China has experienced a dramatic change in indoor environmental exposures during the past two decades.However,such changes and their associations with children’s asthma and other health aspects have not been thoroughly studied.China,Children,Homes,Health(CCHH),Phase I,was a cross-sectional questionnaire survey of 48219 children 1–8 years old in 10 Chinese cities during 2010–2012.The questionnaire includes the International Study of Asthma and Allergies in Childhood(ISAAC)core health questions and additional questions regarding housing,life habits and outdoor environment.In health analyses,children aged 3–6 years old were included.The prevalences of doctor diagnosed asthma varied from 1.7%to 9.8%(mean 6.8%),a large increase from 0.91%in 1999 and 1.50%in2000.The prevalence of wheeze,rhinitis and atopic eczema(last 12 months)varied from 13.9%to 23.7%,24.0%to 50.8%and4.8%to 15.8%,respectively.Taiyuan had the lowest prevalences of all illnesses and Shanghai the highest,except for wheezewhere the highest value was for Urumqi.We found(1)no obvious association between disease prevalences and ambient PM10concentrations and(2)higher prevalences of disease in humid climates with hot summers and cold winters,but with no centrally heated buildings.Associations between the diseases and economic status as indexed by Gross Domestic Product(GDP)requires further study.
基金supported by the National Natural Science Foundation of China(30800894,71173045,21207083)
文摘Prenatal and early life home environment might be related to children’s asthma or allergic diseases later in life.A cross-sectional epidemiological study was designed and a questionnaire survey was performed in 3700 preschool children in urban areas in Taiyuan,Shanxi Province,China.Questions on children’s asthma and allergic diseases from the International Study on Asthma and Allergies in Childhood(ISAAC)were integrated with questions on home environment from the Swedish Dampness in Buildings and Health(DBH)study,appropriately modified for Chinese life habits.By multivariate regression analyses controlling for age,gender,heredity,location in urban/suburban or rural areas,environmental tobacco smoke(ETS)and breastfeeding,we found that home new furniture(HNF)before birth(referring to 1 year before pregnancy and during pregnancy)was positively associated with wheezing ever(odds ratio(OR)1.23 with 95%CI of 1.03–1.48)and wheezing last 12 months(1.24,1.00–1.54),allergic rhinitis(AR)(1.26,1.06–1.51),and eczema(1.42,1.01–1.99).HNF between 0–1 years old was also positively associated with wheezing last 12 months.Home new decoration(HND)during 0–1 years old was positively associated with AR symptoms and eczema symptoms,more in the last 12 months.Stronger positive associations were found for signs of home mold and dampness with almost all children’s asthmatic and allergic symptoms(OR ranging from 1.23–1.85,P<0.05).By mutual adjustment between HNF before children’s birth and home mold or dampness,all the significance remained unchanged.Prenatal HNF and home mold or dampness was independently associated with children’s asthmatic and allergic diseases later in life.
基金supported by the National Natural Science Foundation of China(30800894,71173045)
文摘In order to evaluate the prevalence of childhood asthma,allergic diseases and pneumonia in Urumqi City,China,as well as its associations with housing and home characteristics,a cross-sectional study was performed in 4618 children(81.7%response rate,average age 4.7±0.9 year,boys accounting for 53.7%).Questions on children’s asthma and allergic diseases were from the International Study on Asthma and Allergies in Childhood(ISAAC)and were integrated with questions on the home environment from the Dampness in Buildings and Health(DBH)study,slightly modified to account for Chinese building characteristics and life habits.The prevalences of physician diagnosed asthma,allergic rhinitis(AR)and pneumonia were 3.6%,8.7%and 40.9%,respectively.One fourth of children reported wheezing and more than 40%AR symptoms in the last 12 months.Controlling for confounding factors,positive associations were found for home mold/dampness and wheezing(adjusted odds ratio,aOR 1.33,95%CI 1.07 1.66),AR symptoms(1.34,1.09 1.64)last 12 months and physician diagnosed pneumonia(1.33,1.09 1.62).Floor material by wood,PVC or carpeting;and walls by wallpaper,painting or wood material,were positively associated with AR symptoms.Home environmental tobacco smoke(ETS)was positively associated with wheezing(1.23,1.04 1.46)and pneumonia(1.25,1.07 1.45).In conclusion,there was a relatively high prevalence of asthmatic and AR symptoms and diagnosed pneumonia in preschool children in Urumqi.Home signs of mold growth or dampness,windowpane condensation,as well as ETS and interior surface materials emitting chemicals were risk factors for allergic symptoms and pneumonia.
