Electrospinning has recently emerged as a leading technique for generating biomimetic scaffolds made of synthetic and natural polymers for tissue engineering applications. In this study, we prepared polyvinyl alcohol ...Electrospinning has recently emerged as a leading technique for generating biomimetic scaffolds made of synthetic and natural polymers for tissue engineering applications. In this study, we prepared polyvinyl alcohol (PVA) solution as biopolymer material for fabrication of scaffolds tissue by electrospiuning, we optimized the shape and size of the ensuing electrospun fibers by varying of the electrospinning process, such as high voltage with 5-25 kV and polymeric solution rate with 0.2-10 ml/h. Scanning electron microscopy was utilized the topography of individual electrospun fibers. Distribution of mean diameters of the synthesis fibers were measured fi'om scanning electron micrographs. Fibers diameters size related with fibers a count in SEM images as gaussian distribution with maximum peak represented the average fibers diameters. Our results indicate that the average diameter PVA fibers could be scaled down to mean values 80-500 nm without any beads, fibers diameter increased as applied voltage decreased and decrease as polymeric solution flow rate increase to be with 300-580 nm as mean diameters.展开更多
文摘Electrospinning has recently emerged as a leading technique for generating biomimetic scaffolds made of synthetic and natural polymers for tissue engineering applications. In this study, we prepared polyvinyl alcohol (PVA) solution as biopolymer material for fabrication of scaffolds tissue by electrospiuning, we optimized the shape and size of the ensuing electrospun fibers by varying of the electrospinning process, such as high voltage with 5-25 kV and polymeric solution rate with 0.2-10 ml/h. Scanning electron microscopy was utilized the topography of individual electrospun fibers. Distribution of mean diameters of the synthesis fibers were measured fi'om scanning electron micrographs. Fibers diameters size related with fibers a count in SEM images as gaussian distribution with maximum peak represented the average fibers diameters. Our results indicate that the average diameter PVA fibers could be scaled down to mean values 80-500 nm without any beads, fibers diameter increased as applied voltage decreased and decrease as polymeric solution flow rate increase to be with 300-580 nm as mean diameters.