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COVID-19-induced transaminitis and hyperbilirubinemia:Presentation and outcomes
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作者 Zeinab Nabil Ahmed Said safinaz adel el habashy +1 位作者 Samy Zaky ESCMID Study Group for Viral Hepatitis 《World Journal of Gastroenterology》 SCIE CAS 2023年第7期1123-1130,共8页
The risk of liver injury in patients with coronavirus disease 2019(COVID-19)infection is quite evident.Furthermore,liver function test abnormalities are still detected in COVID-19 patients despite the development of a... The risk of liver injury in patients with coronavirus disease 2019(COVID-19)infection is quite evident.Furthermore,liver function test abnormalities are still detected in COVID-19 patients despite the development of antivirals and the availability of several types of vaccines.This editorial describes liver involvement during COVID-19 infection in patients with or without preexisting liver injury,such as chronic liver disease,to elucidate COVID-19-induced liver function abnormalities and their severity,pathophysiology,clinical manifestations,and clinical and laboratory outcomes.We also discuss the effect of vaccination against COVID-19 to better understand host factors,such as age,gender,and race,on the incidence and severity of liver dysfunction at initial presentation and during the illness.Finally,we summarize the results of relevant meta-analyses published to date and highlight the importance of adequate liver function monitoring in the current climate of the overwhelming COVID-19 pandemic. 展开更多
关键词 COVID-19 SARS-CoV-2 Liver injury TRANSAMINASES HYPERBILIRUBINEMIA PATHOPHYSIOLOGY
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