The purpose of this study was to determine whether planned cesarean delivery for the singleton fetus in breech presen-tation at term reduces the risk of dea th or neurodevelop-mental delay at 2years of age.In sele cte...The purpose of this study was to determine whether planned cesarean delivery for the singleton fetus in breech presen-tation at term reduces the risk of dea th or neurodevelop-mental delay at 2years of age.In sele cted centers in the Term Breech Trial,children were screened for abnormali-ties at≥2years of age with the Ages and Stages Ques-tionnaire,followed by a neurodevelopmental assessment if the Ages and Stages Questionnaire sc ore was abnormal.A total of 923of 1159children(79.6%)from 85centers were followed to 2years of age.The risk of death or neu-rodevelopmental delay was no different for the planned ce-sarean than for the planned vaginal birth groups(14chil-dren3.1%vs 13children2.8%;relative risk,1.09;95%CI,0.52-2.30;P =.85;risk diffe rence,+0.3%;95%CI,-1.9%,+2.4%).Planned cesarean delivery is not associated with a red uction in risk of death or neurodevelopmental delay in childr en at 2years of age.展开更多
Objective: To describe parental perspectives on health status and health- related quality of life (HRQL) at age 10 years in children with birth weights less than 1251 g who participated in the multicenter Cryotherapy ...Objective: To describe parental perspectives on health status and health- related quality of life (HRQL) at age 10 years in children with birth weights less than 1251 g who participated in the multicenter Cryotherapy for Retinopathy of Prematurity (CRYO- ROP) study. Methods: In 244 participants in the randomized CRYO- ROP trial and 102 CRYO- ROP participants who did not develop ROP, the Health Utilities Index (HUI)- system was used to characterize health status for the following 8 attributes: vision, hearing, speech, ambulation, dexterity, emotion, cognition, and pain. Using a utility formula, HRQL was determined for each child on a scale from 0.0 (dead) to 1.00 (perfect health). Results: The proportion of the ROPrandomized group with limitations in 4 attributes or more was 20.6% compared with 2.0% for the no- ROP group. Within the ROP- randomized group, the proportion of “ sighted” children with limitations in 4 attributes or more was 6.4% vs 46.5% in the “ blind/low vision” group. The median HRQL score for the ROP- randomized children was lower than for the no- ROP children (0.72 vs 0.97, P < .001); the median HRQL score for the sighted- randomized children was 0.87 vs 0.27 for the blind/low vision children (P < .001). Conclusions: Threshold ROP was associated with functional limitations in health attributes and reduction in HRQL scores at age 10 years. Furthermore, among children who developed threshold ROP, a greater reduction in HRQL scores was found among children with a poor visual outcome compared with those with better sight.展开更多
文摘The purpose of this study was to determine whether planned cesarean delivery for the singleton fetus in breech presen-tation at term reduces the risk of dea th or neurodevelop-mental delay at 2years of age.In sele cted centers in the Term Breech Trial,children were screened for abnormali-ties at≥2years of age with the Ages and Stages Ques-tionnaire,followed by a neurodevelopmental assessment if the Ages and Stages Questionnaire sc ore was abnormal.A total of 923of 1159children(79.6%)from 85centers were followed to 2years of age.The risk of death or neu-rodevelopmental delay was no different for the planned ce-sarean than for the planned vaginal birth groups(14chil-dren3.1%vs 13children2.8%;relative risk,1.09;95%CI,0.52-2.30;P =.85;risk diffe rence,+0.3%;95%CI,-1.9%,+2.4%).Planned cesarean delivery is not associated with a red uction in risk of death or neurodevelopmental delay in childr en at 2years of age.
文摘Objective: To describe parental perspectives on health status and health- related quality of life (HRQL) at age 10 years in children with birth weights less than 1251 g who participated in the multicenter Cryotherapy for Retinopathy of Prematurity (CRYO- ROP) study. Methods: In 244 participants in the randomized CRYO- ROP trial and 102 CRYO- ROP participants who did not develop ROP, the Health Utilities Index (HUI)- system was used to characterize health status for the following 8 attributes: vision, hearing, speech, ambulation, dexterity, emotion, cognition, and pain. Using a utility formula, HRQL was determined for each child on a scale from 0.0 (dead) to 1.00 (perfect health). Results: The proportion of the ROPrandomized group with limitations in 4 attributes or more was 20.6% compared with 2.0% for the no- ROP group. Within the ROP- randomized group, the proportion of “ sighted” children with limitations in 4 attributes or more was 6.4% vs 46.5% in the “ blind/low vision” group. The median HRQL score for the ROP- randomized children was lower than for the no- ROP children (0.72 vs 0.97, P < .001); the median HRQL score for the sighted- randomized children was 0.87 vs 0.27 for the blind/low vision children (P < .001). Conclusions: Threshold ROP was associated with functional limitations in health attributes and reduction in HRQL scores at age 10 years. Furthermore, among children who developed threshold ROP, a greater reduction in HRQL scores was found among children with a poor visual outcome compared with those with better sight.
