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垂体腺瘤压迫下丘脑患者的下尿路功能
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作者 Yamamoto T. sakakibara r. +1 位作者 Uchiyama T. 胡慧敏 《世界核心医学期刊文摘(神经病学分册)》 2005年第7期25-25,共1页
Background: The micturition reflex is under the tonic influence of suprapontin e structures including the anteromedial frontal cortex, basal ganglia, and hypot halamus. However, there have been few reports about the r... Background: The micturition reflex is under the tonic influence of suprapontin e structures including the anteromedial frontal cortex, basal ganglia, and hypot halamus. However, there have been few reports about the role of the hypothalamus on the lower urinary tract (LUT) function in humans. Objective: To investigate LUT function in patients with pituitary adenomas.Methods: Urodynamic studies wer e carried out in three patients with LUT symptoms who had pituitary adenomas ext ending upwards to the hypothalamus. Results: All three male patients(age 28 to 6 2 years) developed LUT symptoms (urinary urgency and frequency (3); urinary inco ntinence (3); voiding difficulty and retention (2)) along with weight loss, psyc hiatric symptoms,unsteady gait, and/or visual disturbances. One had the syndrome of inappropriate secretion of antidiuretic hormone,but none had diabetes insipi dus. Two had resection of the tumour and subsequent radiation therapy, but LUT d ysfunction persisted. The third patient had partial resection of the tumour to a meliorate hydrocephalus. Urodynamic studies showed detrusorover activity during the storage phase in all patients; during the voiding phase there was underactiv e detrusor in two andnon-relaxing sphincter in one. Conclusions: Hypothalamic l esions can cause severe LUT dysfunction in both the storage and voiding phases o f micturition. This may reflect the crucial role of the hypothalamus in regulati ng micturition in humans. 展开更多
关键词 垂体腺瘤 下尿路 肿瘤切除术 基底神经节 额叶皮质 排尿反射 PITUITARY 术后放射治疗 tumour 逼尿肌反射亢进
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关于壳核出血中断丘脑皮层向次级躯体感觉皮层投射的病例报道
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作者 Hiraga A. sakakibara r. +1 位作者 Mizobuchi K. 张玉龙 《世界核心医学期刊文摘(神经病学分册)》 2005年第8期49-49,共1页
Putaminal hemorrhage presenting pure sensory stroke is rare.We describe a case of left putaminal hemorrhage presenting contral ateral hemisensory disturbance without hemiparesis. A 52-year-old man developed analgesia ... Putaminal hemorrhage presenting pure sensory stroke is rare.We describe a case of left putaminal hemorrhage presenting contral ateral hemisensory disturbance without hemiparesis. A 52-year-old man developed analgesia and thermoanesthesi a in the right half of his body, but deep sensation was relatively well preserve d. Neuroradiological and somatosensory evoked potential findings suggested that thalamocortical sensory pathways to the secondary somatosensory cortex (S2)were involved, whereas those to the primary somatosensory cortex(S1) were spared. In experimental animals, spinothalamic projections from the thalamic nucleus input directly to S2. In humans, thalamocortical pathways are still a subject of debat e,but results of recent functional imaging studies suggest that the pathway of p ain inputs directly to S2 and that of tactile sensation to S2 via S1. Our findin gs support these reports. 展开更多
关键词 感觉皮层 壳核出血 丘脑核 感觉障碍 深感觉 感觉性 功能影像学 神经放射学 试验结果 痛温觉
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腰椎关节强直是否为老年女性尿潴留的诱因
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作者 sakakibara r. Yamamoto T. +1 位作者 Uchiyama T. 史利利 《世界核心医学期刊文摘(神经病学分册)》 2005年第12期34-35,共2页
Abstract:Objectives: Lumbar spondylosis (LS) is a common spinal degenerative disorder which causes various types of lower urinary tract dysfunction (LUTD). However, it is not certain whether LS may cause urinary reten... Abstract:Objectives: Lumbar spondylosis (LS) is a common spinal degenerative disorder which causes various types of lower urinary tract dysfunction (LUTD). However, it is not certain whether LS may cause urinary retention in elderly women. Methods: In a period covering the past 3 years, we retrospectively reviewed: a) urodynamic case records of women with urinary retention (post-void residuals, PVR > 100 ml), b) the records of women with LUTD due to LS (cauda equina syndrome and spinal canal narrowing by MRI), and c) uro-neurological features of women who belonged to both a) and b). Results: a) One-hundred women with a mean age of 58 years had urinary retention. The most common underlying disease was multiple system atrophy [19], followed by multiple sclerosis [13] and cervical/thoracic tumours [8]. LS was the fourth most common [5], with the highest age (71 years) of all diseases. b) Nineteen women with LUTD had LS (12, canal narrowing of 50-70%; 7 > 70 %), with a mean PVR volume of 60 ml. A fourth [5] of them had urinary retention, with severe spinal canal narrowing (all 5 > 70%). c) Thus, 5 women belonged to both a) and b). In 4 of these women, LUTD followed or occurred together with typical cauda equina syndrome symptoms such as sciatica and saddle anesthesia. However, one elderly woman presented with painless urinary retention, and absent ankle reflexes were the sole neurological abnormality. The urodynamic abnormalities underlying urinary retention included an underactive detrusor in all 5, bladder sensory impairment in 3, an unrelaxing sphincter in 2, a low compliance detrusor in one, neurogenic sphincter motor unit potentials in 2 of 4 studied, and cholinergic supersensitivity of the detrusor in one of 3 studied. Surgical decompression ameliorated urinary retention in 1 of 2 women who had surgery. Conclusions: In our series, only 5 percent of the women with urinary retention had LS, but LS poses a potential risk for retention, particularly in elderly women with severe spinal canal narrowing. Preganglionic somato-autonomic dysfunctions underlie this condition. It may appear as the sole initial complaint in cases in which no other obvious neurological abnormalities are found. 展开更多
关键词 性尿潴留 关节强直 退行性病变 椎管狭窄 神经功能障碍 马尾综合征 尿动力学 多发性硬化症 多系统萎缩 感觉障碍
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