There is currently no consensus among clinicians and scientists over the appropriate or optimal timing for umbilical cord clamping. However, many clinical studies have suggested that delayed cord clamping is associate...There is currently no consensus among clinicians and scientists over the appropriate or optimal timing for umbilical cord clamping. However, many clinical studies have suggested that delayed cord clamping is associated with various neonatal benefits including increased blood volume, reduced need for blood transfusion, increased cerebral oxygenation in pre-term infants, and decreased frequency of iron deficiency anemia in term infants. Human umbilical cord blood con- tains significant amounts of stem and progenitor cells and is currently used in the treatment of several life-threatening diseases. We propose that delayed cord clamping be encouraged as it en- hances blood flow from the placenta to the neonate, which is accompanied by an increase supply of valuable stem and progenitor cells, as well as may improve blood oxygenation and increase blood volume, altogether reducing the infant＇s susceptibility to both neonatal and age-related diseases.展开更多
Bioethics falls within the controversial ethical issues from the new advances and emerging technology in pre-clinical and clinical settings which inspired medical policy and practice.The purpose of this paper is to pr...Bioethics falls within the controversial ethical issues from the new advances and emerging technology in pre-clinical and clinical settings which inspired medical policy and practice.The purpose of this paper is to present an overview of ethical issues in stem cell-based therapies and to provide substantial argument for the need ofa Bioethics Research Consortium that will be tasked with convening a disciplined board of experts that will apply their principles to biomedical research,and emerging technology to further stipulate the socioeconomic influence of such entities and their therapeutic impact to society.Not too long ago,the successful therapeutic studies in Parkinson's disease and stroke were the highlights of bioethical issues.The precedent for study selection was based on public feedback,government reception,and scientific analyses developed by these spearhead studies.From all the negative publicity that researchers have been getting before,the whiplash from decades of fear and misunderstanding has hindered the progress of scientific study.There is a huge figurative tug of war between what is making profit and what is needed to improve the health of afflicted patients worldwide.Poor management of education and funding may have actually hindered potential life changing cures and treatments from coming to fruition.We propose the creation of a Bioethics Research Consortium that would determine how ethical matters are handled with careful consideration to public need.The goal is to restructure drug development policy,and improve upon the ways in which research methods and funds are handled today.展开更多
基金funded by NIH NINDS RO1 1R01NS071956-01,NIH NINDS 1R21NS089851-01Department of Defense TATRC W811XWH-11-1-0634+1 种基金Veterans Affairs BX001407-01A2James and Esther King Biomedical Research Program 09KB-01-23123,and 1KG01-33966
文摘There is currently no consensus among clinicians and scientists over the appropriate or optimal timing for umbilical cord clamping. However, many clinical studies have suggested that delayed cord clamping is associated with various neonatal benefits including increased blood volume, reduced need for blood transfusion, increased cerebral oxygenation in pre-term infants, and decreased frequency of iron deficiency anemia in term infants. Human umbilical cord blood con- tains significant amounts of stem and progenitor cells and is currently used in the treatment of several life-threatening diseases. We propose that delayed cord clamping be encouraged as it en- hances blood flow from the placenta to the neonate, which is accompanied by an increase supply of valuable stem and progenitor cells, as well as may improve blood oxygenation and increase blood volume, altogether reducing the infant＇s susceptibility to both neonatal and age-related diseases.
文摘Bioethics falls within the controversial ethical issues from the new advances and emerging technology in pre-clinical and clinical settings which inspired medical policy and practice.The purpose of this paper is to present an overview of ethical issues in stem cell-based therapies and to provide substantial argument for the need ofa Bioethics Research Consortium that will be tasked with convening a disciplined board of experts that will apply their principles to biomedical research,and emerging technology to further stipulate the socioeconomic influence of such entities and their therapeutic impact to society.Not too long ago,the successful therapeutic studies in Parkinson's disease and stroke were the highlights of bioethical issues.The precedent for study selection was based on public feedback,government reception,and scientific analyses developed by these spearhead studies.From all the negative publicity that researchers have been getting before,the whiplash from decades of fear and misunderstanding has hindered the progress of scientific study.There is a huge figurative tug of war between what is making profit and what is needed to improve the health of afflicted patients worldwide.Poor management of education and funding may have actually hindered potential life changing cures and treatments from coming to fruition.We propose the creation of a Bioethics Research Consortium that would determine how ethical matters are handled with careful consideration to public need.The goal is to restructure drug development policy,and improve upon the ways in which research methods and funds are handled today.
