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FPGA-based Acceleration of Davidon-Fletcher-Powell Quasi-Newton Optimization Method 被引量:2
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作者 Liu Qiang sang ruoyu Zhang Qijun 《Transactions of Tianjin University》 EI CAS 2016年第5期381-387,共7页
Quasi-Newton methods are the most widely used methods to find local maxima and minima of functions in various engineering practices. However, they involve a large amount of matrix and vector operations, which are comp... Quasi-Newton methods are the most widely used methods to find local maxima and minima of functions in various engineering practices. However, they involve a large amount of matrix and vector operations, which are computationally intensive and require a long processing time. Recently, with the increasing density and arithmetic cores, field programmable gate array(FPGA) has become an attractive alternative to the acceleration of scientific computation. This paper aims to accelerate Davidon-Fletcher-Powell quasi-Newton(DFP-QN) method by proposing a customized and pipelined hardware implementation on FPGAs. Experimental results demonstrate that compared with a software implementation, a speed-up of up to 17 times can be achieved by the proposed hardware implementation. 展开更多
关键词 QUASI-NEWTON method hardware ACCELERATION field PROGRAMMABLE gate array
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近红外二区有机小分子荧光探针 被引量:15
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作者 桑若愚 许兴鹏 +2 位作者 王其 范曲立 黄维 《化学学报》 SCIE CAS CSCD 北大核心 2020年第9期901-915,共15页
荧光成像凭借灵敏度高、特异性强等诸多优势在重大疾病的诊疗领域发挥着重要作用.然而传统的近红外一区(NIR-I,700~900nm)荧光成像存在组织穿透性差等问题,限制了其临床应用.近红外二区(NIR-II,1000~1700nm)荧光成像可以极大地减弱生物... 荧光成像凭借灵敏度高、特异性强等诸多优势在重大疾病的诊疗领域发挥着重要作用.然而传统的近红外一区(NIR-I,700~900nm)荧光成像存在组织穿透性差等问题,限制了其临床应用.近红外二区(NIR-II,1000~1700nm)荧光成像可以极大地减弱生物组织对光的吸收、散射和自发荧光,从而显著提升成像深度及成像效果.在众多NIR-II荧光探针中,有机小分子由于具有毒性低、代谢快等优点正成为该领域的研究热点.作者以近年来NIR-II有机小分子荧光探针的发展为主体,概括了提升探针荧光量子产率的策略,分别就可激活型、多模态成像型和诊疗一体化型NIR-II荧光探针进行分类讨论,系统介绍了近年来该领域内的研究成果,并针对NIR-II荧光探针未来的发展进行了展望. 展开更多
关键词 近红外二区荧光成像 有机小分子 可激活探针 多模态成像 光学治疗
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