Natural Nanoskin Advance cell therapy (ACT) and Nanoskin ACT Soft have been established to be remarkably versatile biomaterials and can be used in a wide variety of applied scientific endeavors, especially for medical...Natural Nanoskin Advance cell therapy (ACT) and Nanoskin ACT Soft have been established to be remarkably versatile biomaterials and can be used in a wide variety of applied scientific endeavors, especially for medical devices. In fact, the structure of Nanoskin materials can be adapted over length scales ranging from nano to macro by controlling the bio-fabrication process. The present paper describes Natural Nanoskin Advanced cell therapy (ACT) and Nanoskin ACT Soft production for wound care applications. ACT is produced from the bio-nanotechnology process. ACT is a highly hydrated pellicle with shaped fibers less than 2 nm wide. Nanoskin ACT Soft, like a paste, is designed to fill irregularities or recesses in the wound bed, and to absorb excess exudate from lesions by prolonging the used dressing's residence time and reducing the frequency of change.展开更多
Natural extracellular matrices (ECMs) perform the tasks necessary for tissue formation, maintenance, regulation and function, providing a powerful means of controlling the biological performance of regenerative materi...Natural extracellular matrices (ECMs) perform the tasks necessary for tissue formation, maintenance, regulation and function, providing a powerful means of controlling the biological performance of regenerative materials. In addition, biomedical materials have claimed attention because of the increased interest in tissue engineering materials for wound care and regenerative medicine. Moreover, the nanostructure and morphological similarities with collagen make BC attractive for cell immobilization, cell support and Natural Extracellular Matrix (ECM) Scaffolds. In this work, we present the extracellular matrix (ECM) using the bacterial cellulose (Nanoskin<sup>®</sup>) which regulates cell behavior by influencing cell proliferation, survival, shape, migration and differentiation. Bacterial cellulose fermentation process is modified before the bacteria are inoculated for mimicking ECM to cells support and built new local material for wound healing. Chemical groups influences and thermal behavior in bacterial cellulose were analyzed using transmission infrared spectroscopy (FTIR) and thermogravimetric analysis (TGA), respectively. Besides, In vivo analysis was evaluated with clinical study at Sharjah Kuwait Hospital.展开更多
Bacterial cellulose (BC) is established as a newest biomaterial, and it can be used for medical and odontology applications. In addition, it has called attention for uses such as membrane for wound care and tissue eng...Bacterial cellulose (BC) is established as a newest biomaterial, and it can be used for medical and odontology applications. In addition, it has called attention for uses such as membrane for wound care and tissue engineering. In this work, the bacterial cellulose fermentation process is modified by the addition of natural materials before the bacteria are inoculated. In vivo behavior using natural ECM for regenerative medicine is presented and completed wound healing process is 3 months.展开更多
文摘Natural Nanoskin Advance cell therapy (ACT) and Nanoskin ACT Soft have been established to be remarkably versatile biomaterials and can be used in a wide variety of applied scientific endeavors, especially for medical devices. In fact, the structure of Nanoskin materials can be adapted over length scales ranging from nano to macro by controlling the bio-fabrication process. The present paper describes Natural Nanoskin Advanced cell therapy (ACT) and Nanoskin ACT Soft production for wound care applications. ACT is produced from the bio-nanotechnology process. ACT is a highly hydrated pellicle with shaped fibers less than 2 nm wide. Nanoskin ACT Soft, like a paste, is designed to fill irregularities or recesses in the wound bed, and to absorb excess exudate from lesions by prolonging the used dressing's residence time and reducing the frequency of change.
文摘Natural extracellular matrices (ECMs) perform the tasks necessary for tissue formation, maintenance, regulation and function, providing a powerful means of controlling the biological performance of regenerative materials. In addition, biomedical materials have claimed attention because of the increased interest in tissue engineering materials for wound care and regenerative medicine. Moreover, the nanostructure and morphological similarities with collagen make BC attractive for cell immobilization, cell support and Natural Extracellular Matrix (ECM) Scaffolds. In this work, we present the extracellular matrix (ECM) using the bacterial cellulose (Nanoskin<sup>®</sup>) which regulates cell behavior by influencing cell proliferation, survival, shape, migration and differentiation. Bacterial cellulose fermentation process is modified before the bacteria are inoculated for mimicking ECM to cells support and built new local material for wound healing. Chemical groups influences and thermal behavior in bacterial cellulose were analyzed using transmission infrared spectroscopy (FTIR) and thermogravimetric analysis (TGA), respectively. Besides, In vivo analysis was evaluated with clinical study at Sharjah Kuwait Hospital.
文摘Bacterial cellulose (BC) is established as a newest biomaterial, and it can be used for medical and odontology applications. In addition, it has called attention for uses such as membrane for wound care and tissue engineering. In this work, the bacterial cellulose fermentation process is modified by the addition of natural materials before the bacteria are inoculated. In vivo behavior using natural ECM for regenerative medicine is presented and completed wound healing process is 3 months.
